LOCUS BC112165 4386 bp mRNA linear HUM 21-JAN-2006
DEFINITION Homo sapiens Cdc42 GTPase-activating protein, mRNA (cDNA clone
MGC:138370 IMAGE:8327633), complete cds.
ACCESSION BC112165
VERSION BC112165.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4386)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4386)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-JAN-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 4 Row: j Column: 15.
FEATURES Location/Qualifiers
source 1..4386
/db_xref="H-InvDB:HIT000340294"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:138370 IMAGE:8327633"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_313"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: CATACCAC"
gene 1..4386
/gene="CDGAP"
/gene_synonym="KIAA1204"
/db_xref="GeneID:57514"
CDS 28..4362
/gene="CDGAP"
/gene_synonym="KIAA1204"
/codon_start=1
/product="Cdc42 GTPase-activating protein"
/protein_id="AAI12166.1"
/db_xref="GeneID:57514"
/translation="MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEF
IETHGIVDGIYRLSGVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFREL
PNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQELPPSHYRTLEYLIRHLAHIASFS
SKTNMHARNLALVWAPNLLRSKEIEATGCNGDAAFLAVRVQQVVIEFILNHVDQIFNN
GAPGSLENDENRPIMKSLTLPALSLPMKLVSLEEAQARSLATNHPARKERRENSLPEI
VPPMGTLFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRL
SVEKATIRPAKSMDSLCSVPVEGKETKGNFNRTVTTGGFFIPATKMHSTGTGSSCDLT
KQEGEWGQEGMPPGAEGGFDVSSDRSHLQGAQARPPPEQLKVFRPVEDPESEQTAPKM
LGMFYTSNDSPSKSVFTSSLFQMEPSPRNQRKALNISEPFAVSVPLRVSAVISTNSTP
CRTPPKELQSLSSLEEFSFHGSESGGWPEEEKPLGAETSAASVPKKAGLEDAKAVPEA
PGTVECSKGLSQEPGAHLEEKKTPESSLSSQHLNELEKRPNPEKVVEEGREAGEMESS
TLQESPRARAEAVLLHEMDEDDLANALIWPEIQQELKIIESEEELSSLPPPALKTSPI
QPILESSLGPFIPSEPPGSLPCGSFPAPVSTPLEVWTRDPANQSTQGASTAASREKPE
PEQGLHPDLASLAPLEIVPFEKASPQATVEVGGPGNLSPPLPPAPPPPTPLEESTPVL
LSKGSPEREDSSRKLRTDLYIDQLKSQDSPEISSLCQGEEATPRHSDKQNSKNAASEG
KGCGFPSPTREVEIVSQEEEDVTHSVQEPSDCDEDDTVTDIAQHGLEMVEPWEEPQWV
TSPLHSPTLKDAHKAQVQGLQGHQLEKRLSHRPSLRQSHSLDSKPTVKSQWTLEVPSS
SSCANLETERNSDPLQPQAPRREITGWDEKALRSFREFSGLKGAEAPPNQKGPSGVQP
NPAETSPISLAEGKELGTHLGHSSPQIRQGGVPGPESSKESSPSVQDSTSPGEHPAKL
QLKSTECGPPKGKNRPSSLNLDPAIPIADLFWFENVASFSSPGMQVSEPGDPKVTWMT
SSYCKADPWRVYSQDPQDLDIVAHALTGRRNSAPVSVSAVRTSFMVKMCQARAVPVIP
PKIQYTQIPQPLPSQSSGENGVQPLERSQEGPSSTSGTTQKPAKDDSPSSLESSKEEK
PKQDPGAIKSSPVDATAPCMCEGPTLSPEPGSSNLLSTQDAVVQCRKRMSETEPSGDN
LLSSKLERPSGGSKPFHRSRPGRPQSLILFSPPFPIMDHLPPSSTVTDSKVLLSPIRS
PTQTVSPGLLCGELAENTWVTPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILD
GRSGRQIE"
BASE COUNT 1139 a 1235 c 1158 g 854 t
ORIGIN
1 gaggggcagc ctctttggga ctaactcatg aagaacaagg gtgctaagca gaagctgaaa
61 cgaaagggag ccgccagcgc gtttggctgt gacctgacgg agtatctgga aagctcggga
121 caggatgttc catacgtttt gaagagctgt gcagaattta tagagactca cggcatcgtg
181 gatggaatct atcggctttc aggagtcacc tcaaacatac aacggctaag gcaagagttt
241 ggctcagatc aatgtccaga tctgacaagg gaagtgtacc tccaggacat ccactgtgtg
301 ggctcgcttt gcaagctcta ctttagggag ctgcccaacc ccctcctgac ttatgagctc
361 tatgagaaat tcacggaggc agtgtcgcat tgccctgaag aaggccaact ggcccgaatc
421 caaaatgtta tccaggagct tcctccatcc cactatagga ccttggaata cctgattcga
481 cacctggccc atatcgcctc cttcagcagc aagaccaaca tgcacgcccg gaacctggcc
541 ctggtgtggg cgccaaacct cctcaggtct aaagaaattg aagccactgg ttgcaatgga
601 gatgcagcct tccttgcagt ccgggtccag caggtggtga ttgagttcat attgaatcat
661 gtagatcaaa tctttaacaa cggtgcacct gggtctctgg agaatgatga aaaccggccc
721 atcatgaaga gcctgacctt gccagccctc tccctgccca tgaagctggt gagccttgag
781 gaagctcaag cccgcagcct ggccactaac catcctgctc gcaaggaaag gagggagaac
841 agcctgcctg agattgtccc tcccatgggc accctcttcc acactgtcct tgagttacca
901 gacaacaagc gaaagctctc cagtaaatca aagaagtgga aatcaatatt taacctggga
961 cgttctggat cagactccaa atcaaaactg agtagaaatg ggagtgtatt tgtgagagga
1021 cagaggctct cggtggaaaa ggctactatc cgaccagcta aaagcatgga ctcactatgt
1081 tcagtgcctg tggaaggaaa agaaaccaag ggaaatttca atcgaacagt taccaccggt
1141 ggatttttca ttccagcaac aaagatgcac tccaccggca ccggcagctc atgtgacctc
1201 accaagcagg agggcgaatg gggccaggag gggatgcctc ccggggctga gggtggcttt
1261 gatgtgagca gtgatcgcag ccatctccag ggcgctcagg cccggccccc accggaacag
1321 ctgaaggttt tccggcctgt tgaggatccg gagagcgagc aaacagcccc aaagatgttg
1381 ggtatgttct acacttcgaa cgacagccct agcaaatccg tcttcaccag cagcctcttc
1441 cagatggagc cctcgccgcg taaccagcgc aaggcgctga acatctccga gccctttgcg
1501 gtatctgtgc cgctccgcgt gtccgcagtc atcagcacca acagcacgcc gtgcagaaca
1561 cccccgaagg agctgcagtc tctttccagc ctggaagagt tttcttttca tggatcagag
1621 agcggaggct ggccagaaga agagaaaccg ctgggagctg agacttctgc agcttctgta
1681 cctaagaagg caggtcttga ggatgccaag gcagtacctg aagcaccggg gacagtggaa
1741 tgcagcaaag gcctgtccca ggagccaggc gcccacctgg aggagaagaa aaccccagaa
1801 agctccttga gctctcaaca tttaaatgaa ttagagaaga ggccaaatcc ggagaaggtg
1861 gtggaggagg gacgagaggc tggtgagatg gagtccagca ccctgcagga gagccccagg
1921 gccagagccg aagctgtgct tctccatgag atggatgaag atgatctggc caatgccctg
1981 atctggcctg agattcaaca ggagctgaaa atcattgaat ctgaggagga gctctcatcg
2041 ttgccacctc ctgctctgaa gaccagccca attcagccta ttctcgagtc gagtctgggg
2101 ccctttattc cctcagagcc tcctgggagc ttgccttgtg gctccttccc tgctccagtc
2161 tccacccctc tggaggtgtg gactagggat ccagccaatc agagcacaca gggggcttcc
2221 acagcagcca gcagagagaa gccggaacct gagcagggcc tgcacccaga cctcgccagc
2281 ctggctcctc tggaaatagt tccttttgag aaggcatctc cacaagcaac agtggaagta
2341 ggaggcccag gcaatctgtc tcctccactc ccacctgctc ctccccctcc aactcctctg
2401 gaggagtcaa ctccagtcct gctttcaaag ggcagcccgg aaagagaaga ctcatccagg
2461 aaattgagga cagatctcta catagaccag ctgaagtccc aagacagccc tgagatctct
2521 agcctctgtc agggagagga ggcaacccca agacacagtg acaagcaaaa ttcaaagaat
2581 gctgcttctg aggggaaagg ctgtggtttt ccaagcccaa ccagggaggt tgagatcgtc
2641 tcacaagaag aggaggatgt aacccattca gtacaggagc cttcagactg tgacgaagat
2701 gacactgtga cagacattgc ccagcatggc ctggagatgg tggagccctg ggaggaaccc
2761 cagtgggtga cgagtcccct tcactctccc accctgaaag acgcgcacaa ggcccaggta
2821 cagggccttc agggtcacca gttggagaag aggctttccc acaggcccag ccttcgccag
2881 agccattctc tagatagcaa acccacggtt aaaagccagt ggactctcga ggttccctcc
2941 tccagcagct gtgctaatct tgaaacagag aggaattctg accctcttca gccccaggca
3001 cccaggagag agattactgg atgggatgag aaagccctga ggtccttcag agagttctct
3061 ggcctgaaag gggcagaggc tcctcccaac cagaagggac caagtggtgt gcaacccaac
3121 ccagcagaaa ccagccccat cagcctagca gagggaaagg agctagggac acacctgggg
3181 cacagcagtc cacagattag gcaaggtggt gttcctgggc cagagagcag caaggagagt
3241 tcacccagcg tgcaggacag cacttcgcct ggagagcacc ccgcaaagtt acagctaaag
3301 agcacagagt gtgggccccc aaaagggaaa aacaggcctt cttccctcaa cttggaccct
3361 gccattccca ttgctgacct cttctggttt gagaatgtgg cctcatttag ttcacctgga
3421 atgcaggtct ctgagccagg agacccaaag gtcacatgga tgacctcatc ttactgtaaa
3481 gcagacccct ggagggttta ctcccaggac ccccaggacc tggacattgt tgctcatgca
3541 ctgacaggcc gccgtaactc agctcctgtg agtgtgtcag ctgtgagaac ctccttcatg
3601 gtcaaaatgt gccaggccag ggcggtccca gtcatccctc ccaagattca gtacacccag
3661 atcccacagc ccctgccctc tcagagctca ggggagaatg gggttcagcc tctggagagg
3721 agccaggagg gacccagctc aaccagtggg accactcaga aacctgccaa agatgattct
3781 ccctcctccc tggaaagctc aaaggaagaa aaaccaaagc aagatcccgg agccattaag
3841 tcctcaccag tggatgccac tgcaccctgc atgtgcgagg gacctaccct ttctccagaa
3901 ccaggctcgt ctaacctgct ctccacccag gatgcagtag tgcaatgcag aaagcgcatg
3961 tcagagacag agccatctgg ggacaacctt ctttcttcaa aactagagcg accatctggg
4021 ggttctaagc ctttccacag gtcaaggcca ggaagacctc agagcctaat cttattcagt
4081 cctcctttcc ccattatgga ccacctgccc ccttcatcca cagtgacaga ttccaaggtc
4141 ctgctgtccc ctatcagaag tcccacccag acagtttccc ctggccttct ttgtggagag
4201 ttggcagaaa acacatgggt cacaccagaa ggggttacac ttaggaataa aatgaccatc
4261 cctaagaatg gccagagact agagacctca accagctgtt tttaccagcc tcagcggaga
4321 tcagtaattc tggatggaag aagtgggagg caaatagaat gatttcggtt cacctgctgg
4381 tgtctg
//