LOCUS BC112161 6069 bp mRNA linear HUM 07-AUG-2007
DEFINITION Homo sapiens tumor protein p53 binding protein 1, mRNA (cDNA clone
MGC:138366 IMAGE:8327629), complete cds.
ACCESSION BC112161
VERSION BC112161.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6069)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 6069)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-JAN-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 4 Row: j Column: 11.
FEATURES Location/Qualifiers
source 1..6069
/db_xref="H-InvDB:HIT000340290"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:138366 IMAGE:8327629"
/tissue_type="Cerebellum, Lung, PCR rescued clones"
/clone_lib="NIH_MGC_348"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: ATTGTGTT"
gene 1..6069
/gene="TP53BP1"
/gene_synonym="53BP1"
/gene_synonym="p202"
/db_xref="GeneID:7158"
/db_xref="HGNC:HGNC:11999"
/db_xref="MIM:605230"
CDS 109..6027
/gene="TP53BP1"
/gene_synonym="53BP1"
/gene_synonym="p202"
/codon_start=1
/product="tumor protein p53 binding protein 1"
/protein_id="AAI12162.1"
/db_xref="GeneID:7158"
/db_xref="HGNC:HGNC:11999"
/db_xref="MIM:605230"
/translation="MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLS
RHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCG
SISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGA
EDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKH
EEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAK
EQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAST
PATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPM
DTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPI
PSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSL
TGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDS
ILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG
SQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEE
NMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEH
KEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCA
ENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQ
EKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDI
IPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGK
GDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQ
KTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQ
PMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIER
PSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGE
KPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDG
TEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS
LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEED
GDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSF
SRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAK
WSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEY
FSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTP
LTKAADISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKR
KLITSEEERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNK
TLFLGYAFLLTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGA
GYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQN
YRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASV
KQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIG
FKQHPKYKHDYVSH"
BASE COUNT 1737 a 1376 c 1558 g 1398 t
ORIGIN
1 catcctcggt ttccctgtcc ttgccccggg ccctgggagt gctctggaag gctgcgcagt
61 attggagggg acagaatgac cttccggcct tgagtccctg gggagcagat ggaccctact
121 ggaagtcagt tggattcaga tttctctcag caagatactc cttgcctgat aattgaagat
181 tctcagcctg aaagccaggt tctagaggat gattctggtt ctcacttcag tatgctatct
241 cgacaccttc ctaatctcca gacgcacaaa gaaaatcctg tgttggatgt tgtgtccaat
301 cctgaacaaa cagctggaga agaacgagga gacggtaata gtgggttcaa tgaacatttg
361 aaagaaaaca aggttgcaga ccctgtggat tcttctaact tggacacatg tggttccatc
421 agtcaggtca ttgagcagtt acctcagcca aacaggacaa gcagtgttct gggaatgtca
481 gtggaatctg ctcctgctgt ggaggaagag aagggagaag agttggaaca gaaggagaaa
541 gagaaggaag aagatacttc aggcaatact acacattccc ttggtgctga agatactgcc
601 tcatcacagt tgggttttgg ggttctggaa ctctcccaga gccaggatgt tgaggaaaat
661 actgtgccat atgaagtgga caaagagcag ctacaatcag taaccaccaa ctctggttat
721 accaggctgt ctgatgtgga tgctaatact gcaattaagc atgaagaaca gtccaacgaa
781 gatatcccca tagcagaaca gtccagcaag gacatccctg tgacagcaca gcccagtaag
841 gatgtacatg ttgtaaaaga gcaaaatcca ccacctgcaa ggtcagagga catgcctttt
901 agccccaaag catctgttgc tgctatggaa gcaaaagaac agttgtctgc acaagaactt
961 atggaaagtg gactgcagat tcagaagtca ccagagcctg aggttttgtc aactcaggaa
1021 gacttgtttg accagagcaa taaaacagta tcttctgatg gttgctctac tccttcaagg
1081 gaggaaggtg ggtgttcttt ggcttccact cctgccacca ctctgcatct cctgcagctc
1141 tctggtcaga ggtcccttgt tcaggacagt ctttccacga attcttcaga tcttgttgct
1201 ccttctcctg atgctttccg atctactcct tttatcgttc ctagcagtcc cacagagcaa
1261 gaagggagac aagataagcc aatggacacg tcagtgttat ctgaagaagg aggagagcct
1321 tttcagaaga aacttcaaag tggtgaacca gtggagttag aaaacccccc tctcctgcct
1381 gagtccactg tatcaccaca agcctcaaca ccaatatctc agagcacacc agtcttccct
1441 cctgggtcac ttcctatccc atcccagcct cagttttctc atgacatttt tattccttcc
1501 ccaagtctgg aagaacaatc aaatgatggg aagaaagatg gagatatgca tagttcatct
1561 ttgacagttg agtgttctaa aacttcagag attgaaccaa agaattcccc tgaggatctt
1621 gggctatctt tgacagggga ttcttgcaag ttgatgcttt ctacaagtga atatagtcag
1681 tccccaaaga tggagagctt gagttctcac agaattgatg aagatggaga aaacacacag
1741 attgaggata cggaacccat gtctccagtt ctcaattcta aatttgttcc tgctgaaaat
1801 gatagtatcc tgatgaatcc agcacaggat ggtgaagtac aactgagtca gaatgatgac
1861 aaaacaaagg gagatgatac agacaccagg gatgacatta gtattttagc cactggttgc
1921 aagggcagag aagaaacggt agcagaagat gtttgtattg atctcacttg tgattcgggg
1981 agtcaggcag ttccgtcacc agctactcga tctgaggcac tttctagtgt gttagatcag
2041 gaggaagcta tggaaattaa agaacaccat ccagaggagg ggtcttcagg gtctgaggtg
2101 gaagaaatcc ctgagacacc ttgtgaaagt caaggagagg aactcaaaga agaaaatatg
2161 gagagtgttc cgttgcacct ttctctgact gaaactcagt cccaagggtt gtgtcttcaa
2221 aaggaaatgc caaaaaaaga atgctcagaa gctatggaag ttgaaaccag tgtgattagt
2281 attgattccc ctcaaaagtt ggcaatactt gaccaagaat tggaacataa ggaacaggaa
2341 gcttgggaag aagctacttc agaggactcc agtgttgtca ttgtagatgt gaaagagcca
2401 tctcccagag ttgatgtttc ttgtgaacct ttggagggag tggagaagtg ctcagattcc
2461 cagtcatggg aggatattgc tccagaaata gaaccatgtg ctgagaatag attagacacc
2521 aaggaagaaa agagtgtaga atatgaagga gatctgaaat cagggactgc agaaacagaa
2581 cctgtagagc aagattcttc acagccttcc ttacctttag tgagagcaga tgatccttta
2641 agacttgacc aggagttgca gcagccccaa actcaggaga aaacaagtaa ttcattaaca
2701 gaagactcaa aaatggctaa tgcaaagcag ctaagctcag atgcagaggc ccagaagctg
2761 gggaagccct ctgcccatgc ctcacaaagc ttctgtgaaa gttctagtga aaccccattt
2821 catttcactt tgcctaaaga aggtgatatc atcccaccat tgactggtgc aaccccacct
2881 cttattgggc acctaaaatt ggagcccaag agacacagta ctcctattgg tattagcaac
2941 tatccagaaa gcaccatagc aaccagtgat gtcatgtctg aaagcatggt ggagacccat
3001 gatcccatac ttgggagtgg aaaaggggat tctggggctg ccccagacgt ggatgataaa
3061 ttatgtctaa gaatgaaact ggttagtcct gagactgagg cgagtgaaga gtctttgcag
3121 ttcaacctgg aaaagcctgc aactggtgaa agaaaaaatg gatctactgc tgttgctgag
3181 tctgttgcca gtccccagaa gaccatgtct gtgttgagct gtatctgtga agccaggcaa
3241 gagaatgagg ctcgaagtga ggatcccccc accacaccca tcagggggaa cttgctccac
3301 tttccaagtt ctcaaggaga agaggagaaa gaaaaattgg agggtgacca tacaatcagg
3361 cagagtcaac agcctatgaa gcccattagt cctgtcaagg accctgtttc tcctgcttcc
3421 cagaagatgg tcatacaagg gccatccagt cctcaaggag aggcaatggt gacagatgtg
3481 ctagaagacc agaaagaagg acggagtact aataaggaaa atcctagtaa ggccttgatt
3541 gaaaggccca gccaaaataa cataggaatc caaaccatgg agtgttcctt gagggtccca
3601 gaaactgttt cagcagcaac ccagactata aagaatgtgt gtgagcaggg gaccagtaca
3661 gtggaccaga actttggaaa gcaagatgcc acagttcaga ctgagagggg gagtggtgag
3721 aaaccagtca gtgctcctgg ggatgataca gagtcgctcc atagccaggg agaagaagag
3781 tttgatatgc ctcagcctcc acatggccat gtcttacatc gtcacatgag aacaatccgg
3841 gaagtacgca cacttgtcac tcgtgtcatt acagatgtgt attatgtgga tggaacagaa
3901 gtagaaagaa aagtaactga ggagactgaa gagccaattg tagagtgtca ggagtgtgaa
3961 actgaagttt ccccttcaca gactgggggc tcctcaggtg acctggggga tatcagctcc
4021 ttctcctcca aggcatccag cttacaccgc acatcaagtg ggacaagtct ctcagctatg
4081 cacagcagtg gaagctcagg gaaaggagcc ggaccactca gagggaaaac cagcgggaca
4141 gaacccgcag attttgcctt acccagctcc cgaggaggcc caggaaaact gagtcctaga
4201 aaaggggtca gtcagacagg gacgccagtg tgtgaggagg atggtgatgc aggccttggc
4261 atcagacagg gagggaaggc tccagtcacg cctcgtgggc gtgggcgaag gggccgccca
4321 ccttctcgga ccactggaac cagagaaaca gctgtgcctg gccccttggg catagaggac
4381 atttcaccta acttgtcacc agatgataaa tccttcagcc gtgtcgtgcc ccgagtgcca
4441 gactccacca gacgaacaga tgtgggtgct ggtgctttgc gtcgtagtga ctctccagaa
4501 attcctttcc aggctgctgc tggcccttct gatggcttag atgcctcctc tccaggaaat
4561 agctttgtag ggctccgtgt tgtagccaag tggtcatcca atggctactt ttactctggg
4621 aaaatcacac gagatgtcgg agctgggaag tataaattgc tctttgatga tgggtacgaa
4681 tgtgatgtgt tgggcaaaga cattctgtta tgtgacccca tcccgctgga cactgaagtg
4741 acggccctct cggaggatga gtatttcagt gcaggagtgg tgaaaggaca taggaaggag
4801 tctggggaac tgtactacag cattgaaaaa gaaggccaaa gaaagtggta taagcgaatg
4861 gctgtcatcc tgtccttgga gcaaggaaac agactgagag agcagtatgg gcttggcccc
4921 tatgaagcag taacacctct tacaaaggca gcagatatca gcttagacaa tttggtggaa
4981 gggaagcgga aacggcgcag taacgtcagc tccccagcca cccctactgc ctccagtagc
5041 agcagcacaa cccctacccg aaagatcaca gaaagtcctc gtgcctccat gggagttctc
5101 tcaggcaaaa gaaaacttat cacttctgaa gaggaacggt cccctgccaa gcgaggtcgc
5161 aagtctgcca cagtaaaacc tggtgcagta ggggcaggag agtttgtgag cccctgtgag
5221 agtggagaca acaccggtga accctctgcc ctggaagagc agagagggcc tttgcctctc
5281 aacaagacct tgtttctggg ctacgcattt ctccttacca tggccacaac cagtgacaag
5341 ttggccagcc gctccaaact gccagatggt cctacaggaa gcagtgaaga agaggaggaa
5401 tttttggaaa ttcctccttt caacaagcag tatacagaat cccagcttcg agcaggagct
5461 ggctatatcc ttgaagattt caatgaagcc cagtgtaaca cagcttacca gtgtcttcta
5521 attgcggatc agcattgtcg aacccggaag tacttcctgt gccttgccag tgggattcct
5581 tgtgtgtctc atgtctgggt ccatgatagt tgccatgcca accagctcca gaactaccgt
5641 aattatctgt tgccagctgg gtacagcctt gaggagcaaa gaattctgga ctggcaaccc
5701 cgtgaaaatc ctttccagaa tctgaaggta ctcttggtat cagaccaaca gcagaacttc
5761 ctggagctct ggtctgagat cctcatgact ggtggtgcag cctctgtgaa gcagcaccat
5821 tcaagtgccc ataacaaaga tattgcttta ggggtatttg atgtggtggt gacggacccc
5881 tcatgcccag cctcggtgct gaagtgtgct gaagcattgc agctgcctgt ggtgtcacaa
5941 gagtgggtga tccagtgcct cattgttggg gagagaattg gattcaagca gcatccaaaa
6001 tataaacacg attatgtttc tcactaaaga tacttggtct tactggtttt attccctgct
6061 atcgtggag
//