LOCUS BC112088 2494 bp mRNA linear HUM 21-JAN-2006
DEFINITION Homo sapiens protocadherin gamma subfamily B, 4, transcript variant
2, mRNA (cDNA clone MGC:138293 IMAGE:8327556), complete cds.
ACCESSION BC112088
VERSION BC112088.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2494)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2494)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-JAN-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 4 Row: g Column: 10.
FEATURES Location/Qualifiers
source 1..2494
/db_xref="H-InvDB:HIT000340217"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:138293 IMAGE:8327556"
/tissue_type="Lung, PCR rescued clones"
/clone_lib="NIH_MGC_299"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: GGTCGCCG"
gene 1..2494
/gene="PCDHGB4"
/gene_synonym="CDH20"
/gene_synonym="FIB2"
/gene_synonym="PCDH-GAMMA-B4"
/db_xref="GeneID:8641"
/db_xref="HGNC:HGNC:8711"
/db_xref="IMGT/GENE-DB:8711"
/db_xref="MIM:603058"
CDS 48..2459
/gene="PCDHGB4"
/gene_synonym="CDH20"
/gene_synonym="FIB2"
/gene_synonym="PCDH-GAMMA-B4"
/codon_start=1
/product="protocadherin gamma subfamily B, 4, isoform 2
precursor"
/protein_id="AAI12089.1"
/db_xref="GeneID:8641"
/db_xref="HGNC:HGNC:8711"
/db_xref="IMGT/GENE-DB:8711"
/db_xref="MIM:603058"
/translation="MGSGAGELGRAERLPVLFLFLLSLFCPALCEQIRYRIPEEMPKG
SVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEICGKKPAC
ALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDA
DIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFG
APPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVLQVTATDQDEGVNAE
ITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVE
VIDENDNAPEVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVTCKLEGDVPFKI
LTSSRNTYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVF
SQSSYIVHVAENNPPGASISQVRASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAE
SGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYPALG
PDGSALFDMVPHAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEV
RTARALGDRDAVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPDPSDL
QAELQFYLVVALALISVLFLVAMILAIALRLRRSSSPASWSCFQPGLCVKSESVVPPN
YSEGTLPYSYNLCVAHTGKTEFNFLKCSEQLSSGQDILCGDSSGALFPLCNSSELTSH
QVSFL"
BASE COUNT 589 a 667 c 668 g 570 t
ORIGIN
1 aacccggcgt ctccaggctg gtgagcaagc tgaggagagc aagagggatg gggagcggcg
61 ccggggagct gggccgggct gagaggctgc cagtgctctt tctcttcctg ctgtctttgt
121 tctgcccggc gctctgtgag cagatccgct acaggattcc cgaggaaatg cccaagggct
181 ccgtagtggg gaacctcgcc acggacctgg ggttcagcgt ccaggagtta ccgactcgaa
241 aactgcgcgt cagttcggag aagccttact tcaccgtgag cgcagagagc ggggagttgc
301 ttgtgagcag caggctagac agggaggaga tatgcgggaa gaagccagct tgtgctctgg
361 aatttgaggc tgttgctgaa aatccactga acttttatca cgtgaatgtg gagatcgagg
421 acattaatga ccacacgcca aaattcacgc aaaattcctt tgagctgcaa ataagtgagt
481 ctgcacagcc tggcacacga tttatattag gatctgccca tgatgcggat attggtagca
541 acacactgca gaattaccaa ctcagtccca gtgatcattt ctcactgata aataaagaga
601 aatcagatgg cagtaaatac cctgagatgg tattgaagac acctttggac agagaaaagc
661 agaaatccta ccacttgact ttgactgcct tggactttgg agctccaccc ctaagcagca
721 ctgcacagat acacgttcta gtgactgatg ccaatgataa tgctccagtg ttcagtcaag
781 acgtatacag ggtgagcctt tcagaaaacg tgtacccggg gaccacggtg ctacaggtga
841 ctgccacgga ccaggatgag ggtgtcaatg ccgagattac tttctctttc agtgaagcta
901 gccagatcac ccaatttgac ctgaactcta acaccgggga aattactgtt ttaaatacat
961 tagattttga agaagtcaaa gaatattcca tagttttgga agcaagggac ggtggaggaa
1021 tgattgcgca atgcacagtg gaggtagaag tcatagatga aaatgacaac gccccagaag
1081 tgatattcca gtctctaccc aacctaatta tggaggacgc cgagctggga acacatattg
1141 ctttgctcaa agtccgtgac aaggattcca gacacaatgg agaagtgact tgtaaattgg
1201 aaggtgatgt tccatttaaa atattaactt cttcaagaaa cacgtataaa ttagtgacag
1261 atgctgttct agaccgcgag cagaatccag agtacaatat aaccgttacg gcaacagatc
1321 ggggcaagcc tcccctctcc tccagttcca gcatcaccct gcacattggt gatgtaaatg
1381 acaacgctcc ggttttctca cagtcttcct atatagtcca cgtggccgag aacaacccgc
1441 ctggagcctc tatttcacaa gtcagggctt ctgatccgga cttggggccc aacggccaag
1501 tctcttactg catcatggcc agtgacctgg agcagcggga gctgtcatcc tacgtgtcca
1561 taagcgcgga gagcggggtg gtgttcgcgc agcgcgcctt cgaccacgag cagctgcgcg
1621 ccttcgaact cacactgcag gcccgcgacc agggctcgcc agcgctcagc gcgaacgtga
1681 gcctgcgcgt gttagtggac gaccgcaacg acaatgcgcc acgggtgctg taccccgcgc
1741 tgggtcccga cggctctgcg ctcttcgata tggtgccgca cgctgcagag cctggctact
1801 tggtgaccaa ggtagtggcg gtggacgcag actcaggaca caacgcctgg ctgtcctacc
1861 acgtgctgca ggctagcgag cccgggctct tcagcctggg gctgcgcacg ggcgaagtgc
1921 gcacagcgcg tgccttaggc gacagggacg ccgtccgcca gcgccttctg gtcgccgtgc
1981 gtgacggtgg acagccacca ctctcggcca ctgccacgtt gcacctggtc ttcgccgaca
2041 gcttgcagga ggtgctgccg gatatcactg accgccccga cccctctgac ctccaggctg
2101 agctgcagtt ttacctagtg gtggccttgg ccttgatctc agtgctcttc ctcgtggcca
2161 tgattctggc cattgccttg cgcctgcgac gctcctccag ccccgcctcc tggagctgct
2221 tccagcctgg tctctgtgtt aaatccgaat ccgtggttcc ccccaactac agcgagggga
2281 ctttgcctta ttcctacaat ctatgtgttg cacatacagg aaagacggag tttaatttcc
2341 taaaatgtag tgagcagttg agttcaggac aagacatact ttgcggtgat tcatctgggg
2401 ccttatttcc actttgtaat tccagtgaat tgacttccca tcaggtgagt ttcctttaag
2461 tataatttaa tgctcattgc ctacccattt ctcc
//