LOCUS BC111499 2580 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens resistance to inhibitors of cholinesterase 8 homolog A
(C. elegans), mRNA (cDNA clone MGC:131931 IMAGE:6526180), complete
cds.
ACCESSION BC111499
VERSION BC111499.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2580)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2580)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (28-DEC-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 255 Row: p Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27883865.
FEATURES Location/Qualifiers
source 1..2580
/db_xref="H-InvDB:HIT000339926"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:131931 IMAGE:6526180"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2580
/gene="RIC8A"
/gene_synonym="RIC8"
/gene_synonym="synembryn"
/db_xref="GeneID:60626"
/db_xref="HGNC:HGNC:29550"
/db_xref="MIM:609146"
CDS 162..1754
/gene="RIC8A"
/gene_synonym="RIC8"
/gene_synonym="synembryn"
/codon_start=1
/product="RIC8A protein"
/protein_id="AAI11500.1"
/db_xref="GeneID:60626"
/db_xref="HGNC:HGNC:29550"
/db_xref="MIM:609146"
/translation="MEPRAVAEAVETGEEDVIMEALRSYNQEHSQSFTFDDAQQEDRK
RLAELLVSVLEQGLPPSHRVIWLQSVRILSRDRNCLDPFTSRQSLQALACYADISVSE
GSVPESADMDVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDV
QFFDLRLLFLLTALRTDVRQQLFQELKGVRLLTDTLELTLGVTPEGNPPTLLPSQETE
RAMEILKVLFNITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTEEFHGHAVN
LLGNLPLKCLDVLLTLEPHGDSTEFMGVNMDVIRALLIFLEKRLHKTHRLKESVAPVL
SVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRVAA
EFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKA
SINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTS
LQDAMCETMEQQLSSDPDSDPD"
BASE COUNT 595 a 738 c 728 g 519 t
ORIGIN
1 gcgccaccag acgctgcgcc ccgttaaagc gccaccagac gccgcgcccc gtcccggcct
61 cccccgcgcg ctggcgcggg gctttctggg ccagggcggg gccggcgaac tgcggcccgg
121 aacggctgag gaagggcccg tcccgccttc cccggcgcgc catggagccc cgggcggttg
181 cagaagccgt ggagacgggt gaggaggatg tgattatgga agctctgcgg tcatacaacc
241 aggagcactc ccagagcttc acgtttgatg atgcccaaca ggaggaccgg aagagactgg
301 cggagctgct ggtctccgtc ctggaacagg gcttgccacc ctcccaccgt gtcatctggc
361 tgcagagtgt ccgaatcctg tcccgggacc gcaactgcct ggacccgttc accagccgcc
421 agagcctgca ggcactagcc tgctatgctg acatctctgt ctctgagggg tccgtcccag
481 agtccgcaga catggatgtt gtactggagt ccctcaagtg cctgtgcaac ctcgtgctca
541 gcagccctgt ggcacagatg ctggcagcag aggcccgcct agtggtgaag ctcacagagc
601 gtgtggggct gtaccgtgag aggagcttcc cccacgatgt ccagttcttt gacttgcggc
661 tcctcttcct gctaacggca ctccgcaccg atgtgcgcca gcagctgttt caggagctga
721 aaggagtgcg cctgctaact gacacactgg agctgacgct gggggtgact cctgaaggga
781 acccacccac gctccttcct tcccaagaga ctgagcgggc catggagatc ctcaaagtgc
841 tcttcaacat caccctggac tccatcaagg gggaggtgga cgaggaagac gctgcccttt
901 accgacacct ggggaccctt ctccggcact gtgtgatgat cgctactgct ggagaccgca
961 cagaggagtt ccacggccac gcagtgaacc tcctggggaa cttgcccctc aagtgtctgg
1021 atgttctcct caccctggag ccacatggag actccacgga gttcatggga gtgaatatgg
1081 atgtgattcg tgccctcctc atcttcctag agaagcgttt gcacaagaca cacaggctga
1141 aggagagtgt agctcccgtg ctgagcgtgc tgactgaatg tgcccggatg caccgcccag
1201 ccaggaagtt cctgaaggcc caggtgctgc cccctctgcg ggatgtgagg acacggcctg
1261 aggttgggga gatgctgcgg aacaagcttg tccgcctcat gacacacctg gacacagatg
1321 tgaagagggt ggctgccgag ttcttgtttg tcctgtgctc tgagagtgtg ccccgattca
1381 tcaagtacac aggctatggg aatgctgctg gccttctggc tgccaggggc ctcatggcag
1441 gaggccggcc cgagggccag tactcagagg atgaggacac agacacagat gagtacaagg
1501 aagccaaagc cagcataaac cctgtgaccg ggagggtgga ggagaagccg cctaacccta
1561 tggagggcat gacagaggag cagaaggagc acgaggccat gaagctggtg accatgtttg
1621 acaagctctc caggaacaga gtcatccagc caatggggat gagtccccgg ggtcatctta
1681 cgtccctgca ggatgccatg tgcgagacta tggagcagca gctctcctcg gaccctgact
1741 cggaccctga ctgaggatgg cagctcttct gctcccccat caggactggt gctgcttcca
1801 gagacttcct tggggttgca acctggggaa gccacatccc actggatcca cacccgcccc
1861 cacttctcca tcttagaaac cccttctctt gactcccgtt ctgttcatga tttgcctctg
1921 gtccagtttc tcatctctgg actgcaacgg tcttcttgtg ctagaactca ggctcagcct
1981 cgaattccac agacgaagta ctttcttttg tctgcgccaa gaggaatgtg ttcagaagct
2041 gctgcctgag ggcagggcct acctgggcac acagaagagc atatgggagg gcaggggttt
2101 gggtgtgggt gcacacaaag caagcaccat ctgggattgg cacactggca gagccagtgt
2161 gttggggtat gtgctgcact tcccagggag aaaacctgtc agaactttcc atacgagtat
2221 atcagaacac acccttccaa ggtatgtatg ctctgttgtt cctgtcctgt cttcactgag
2281 cgcagggctg gaggcctctt agacattctc cttggtcctc gttcagctgc ccactgtagt
2341 atccacagtg cccgagttct cgctggtttt ggcaattaaa cctccttcct actggtttag
2401 actacactta caacaaggaa aatgcccctc gtgtgaccat agattgagat ttataccaca
2461 taccacacat agccacagaa acatcatctt gaaataaaga agagttttgg acaaaaaaaa
2521 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//