LOCUS BC111054 3395 bp mRNA linear HUM 08-DEC-2005
DEFINITION Homo sapiens FYVE, RhoGEF and PH domain containing 3, mRNA (cDNA
clone MGC:117260 IMAGE:5751870), complete cds.
ACCESSION BC111054
VERSION BC111054.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3395)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3395)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 233 Row: n Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 32698764.
FEATURES Location/Qualifiers
source 1..3395
/db_xref="H-InvDB:HIT000339868"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:117260 IMAGE:5751870"
/tissue_type="Brain, Lung, Testis, adult, pooled whole"
/clone_lib="NIH_MGC_115"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3395
/gene="FGD3"
/gene_synonym="FLJ00004"
/gene_synonym="ZFYVE5"
/db_xref="GeneID:89846"
/db_xref="HGNC:HGNC:16027"
/db_xref="IMGT/GENE-DB:16027"
/db_xref="MIM:16027"
CDS 466..2643
/gene="FGD3"
/gene_synonym="FLJ00004"
/gene_synonym="ZFYVE5"
/codon_start=1
/product="FGD3 protein"
/protein_id="AAI11055.1"
/db_xref="GeneID:89846"
/db_xref="HGNC:HGNC:16027"
/db_xref="IMGT/GENE-DB:16027"
/db_xref="MIM:16027"
/translation="MESGRGSSTPPGPIAALGMPDTGPGSSSLGKLQALPVGPRAHCG
DPVSLAAAGDGSPDIGPTGELSGSLKIPNRDSGIDSPSSSVAGENFPCEEGLEAGPSP
TVLGAHAEMALDSQVPKVTPQEEADSDVGEEPDSENTPQKADKDAGLAQHSGPQKLLH
IAQELLHTEETYVKRLHLLDQVFCTRLTDAGIPPEVIMGIFSNISSIHRFHGQFLLPE
LKTRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKDVVH
SIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDRKDAERSLELISTA
ANHSNAAIRKVEKMHKLLEVYEQLGGEEDIVNPANELIKEGQIQKLSAKNGTPQDRHL
FLFNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKPNTAHTFIITGRKRSLELQ
TRTEEEKKEWIQIIQATIEKHKQNSETFKAFGGAFSQDEDPSLSPDMPITSTSPVEPV
VTTEGSSGAAGLEPRKLSSKTRRDKEKQSCKSCGETFNSITKRRHHCKLCGAVICGKC
SEFKAENSRQSRVCRDCFLTQPVAPESTEKTPTADPQPSLLCGPLRLSESGETWSEVW
AAIPMSDPQVLHLQGGSQDGRLPRTIPLPSCKLSVPDPEERLDSGHVWKLQWAKQSWY
LSASSAELQQQWLETLSTAAHGDTAQDSPGALQLQVPMGAAAP"
BASE COUNT 844 a 1018 c 975 g 558 t
ORIGIN
1 tgtgtggtgg gggtgctcca ccatagagct ggtcggcatc cacagccacc aggacgctgc
61 cagagcccag gcctgcgcca cgccctgccc agaggcacac ctgcctgctc aaggcaacca
121 gggcaggctc aaggcagcca gggccagctc actgtgtgcc tgtcactgtg tgaagcctgc
181 ttcttcttta tttcgcttag caagtgaggc aggagcatgt aaagctgctg gcagaggaat
241 atctaattta cctcctaaat ggctctactt tgaacctgct gggcaaggaa gagattttca
301 aggaaaccat ctaccgtgtg caagctcctg ccggccaacc ccagacccca gcacggagcc
361 aggcgcctgt gcccgccgac cctcagcatc ctcctcagaa aggctggtgg catcaggaag
421 cccctggcca gcctccacct gagcccagtg agctcagctt taaggatgga gtcaggcagg
481 gggtcctcaa cccctccagg acccattgct gccctaggga tgccagacac tgggcctggc
541 agttcctccc tagggaagct tcaggcgctc cctgttgggc ccagagccca ctgtggggac
601 cctgtcagcc tggctgcagc aggggacggc tctccagaca taggccccac gggagagctg
661 agtggtagct taaagatccc caaccgggac agcgggatcg acagtccctc ctccagtgtg
721 gctggagaga actttccctg cgaggagggc ttggaggctg gcccaagccc cactgtactg
781 ggggcgcacg cagagatggc cctggacagc caggtcccga aggtcacccc ccaggaggag
841 gcggacagcg acgtgggtga ggaacctgac tctgagaaca ccccccagaa ggctgacaag
901 gatgccggcc tggcccagca ctctggcccc cagaagcttc tccacattgc ccaggagctc
961 ctgcacaccg aggagaccta tgtgaagcgg ctgcacctgc tggaccaggt tttctgcacc
1021 aggctgacgg atgcggggat ccctccagaa gtcatcatgg gcatattctc taacatctcc
1081 tccatccacc gcttccacgg gcagttcctg ctgccggagc tgaagacgcg gatcacggag
1141 gagtgggaca caaacccacg gctcggggac atcctgcaga agctggcccc attcctgaag
1201 atgtacggcg agtatgtcaa gaactttgac cgagccgtag ggctggtgag cacgtggacc
1261 cagcgctccc cactgtttaa agacgtcgtc cacagcatcc agaagcagga ggtatgcggg
1321 aacctgacgc tgcagcacca catgctggag cccgtgcaga gggtcccccg gtacgagctg
1381 ctgctcaagg actatctgaa gaggctcccg caggacgccc cagaccggaa ggatgcggag
1441 aggtccttgg agctcatctc cacagccgcc aaccactcca atgctgccat tcggaaagtg
1501 gagaaaatgc acaagctctt ggaggtgtac gagcagctgg gtggggaaga agacattgtc
1561 aacccggcca atgaactgat caaggagggc caaatccaga aactgtcagc caagaacggc
1621 accccccagg accgccacct cttcctgttc aacagcatga tcctttactg tgtgcccaag
1681 ctgcggctca tgggccagaa gttcagcgtc cgggagaaga tggacatctc aggcctccag
1741 gtgcaggata tcgtcaagcc aaacacagca catacattca tcataacggg aagaaaaagg
1801 tccctggagc tgcagacgcg gacagaggaa gagaagaaag aatggattca gatcatccag
1861 gccaccatcg agaagcacaa acagaacagc gaaaccttca aggcttttgg tggcgccttc
1921 agccaggatg aggaccccag cctctctcca gacatgccta tcacgagcac cagccctgtg
1981 gagcctgtgg tgaccaccga aggcagttcg ggtgcagcag ggctcgagcc cagaaaacta
2041 tcctctaaga ccagacgtga caaggagaag cagagctgta agagctgtgg tgagaccttc
2101 aactccatca ccaagaggag gcatcactgc aagctgtgtg gggcggtcat ctgtgggaag
2161 tgctccgagt tcaaggccga gaacagccgg cagagccgtg tctgcagaga ttgtttcctg
2221 acacagccag tggcccctga gagcacagag aagacaccca ctgcagaccc ccagcccagc
2281 ctgctctgcg gccccctgcg gctgtcagag agcggtgaga cctggagcga ggtgtgggcc
2341 gccatcccca tgtcagatcc ccaggtgctg cacctgcagg gaggcagcca ggacggccgg
2401 ctgccccgca ccatccctct ccccagctgc aaactgagtg tgccggaccc tgaggagagg
2461 ctggactcgg ggcatgtgtg gaagctgcag tgggccaagc agtcctggta cctgagcgcc
2521 tcctccgcag agctgcagca gcagtggctg gaaaccctaa gcactgctgc ccatggggac
2581 acggcccagg acagcccggg ggccctgcag cttcaggtcc ctatgggcgc agctgctccg
2641 tgagctgagt ctcccactgc cctgcacacc accacattgg acctgtgctg tcctgggagg
2701 tggtgttgga ggccccatga agagcgccct ggactgctga gggtgggcca acagcccaga
2761 gctcaggaca cttggctttg gggggaagga aactgaggcc cagagagggg caaccactgg
2821 ccaagggtca cccagcaagt tttggctaag agcctggcct ccagccccag cagtgtggcc
2881 cagagcaggg gccgactgcc aaagtaacca tcatccatat gggccgtgtg gtgatgctgg
2941 cccggaaggc agaaagaggc agcatgggca ctgccaggga cagccacatc ctgctggtct
3001 gcagcgtggt ccaccccgcc tctgcccagc ctgtctacac cgtgtgagct gaatcgtgac
3061 ttgcttccca cctcctttct ctgtcctctc ctgaggttct gcctgcagcc cccaggaggt
3121 gggcctgccc catcctagct ggactcatgg ttcctaaata accacgctca gaagctctgc
3181 taggacttac cccagccact gagtggcagg cgcatgagat ttgtggctgt tcctgatgct
3241 agtggcacac agtgcttatc tgcataaata aacactggcc accaaaaaaa aaaaaaaaaa
3301 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3361 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//