LOCUS BC110875 2489 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens phosphoribosyl pyrophosphate synthetase 2, mRNA (cDNA
clone MGC:131896 IMAGE:6472836), complete cds.
ACCESSION BC110875
VERSION BC110875.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2489)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2489)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 255 Row: o Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31543442.
FEATURES Location/Qualifiers
source 1..2489
/db_xref="H-InvDB:HIT000339766"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:131896 IMAGE:6472836"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2489
/gene="PRPS2"
/gene_synonym="PRS II"
/gene_synonym="PRSII"
/db_xref="GeneID:5634"
/db_xref="HGNC:HGNC:9465"
/db_xref="MIM:311860"
CDS 78..1034
/gene="PRPS2"
/gene_synonym="PRS II"
/gene_synonym="PRSII"
/codon_start=1
/product="phosphoribosyl pyrophosphate synthetase 2"
/protein_id="AAI10876.2"
/db_xref="GeneID:5634"
/db_xref="HGNC:HGNC:9465"
/db_xref="MIM:311860"
/translation="MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEI
GESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDK
SRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIA
EWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAIL
VDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIP
QEDKMKHCTKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL"
BASE COUNT 710 a 518 c 526 g 735 t
ORIGIN
1 gcctcccgcg tcgctgtcgc tgttgcctcc gccacctcct ccgccgccgc gcgcccctcg
61 gagttccgcg ccccaccatg cccaacatcg tgctgttcag cggcagctcg catcaggacc
121 tgtcccagcg cgtggccgac cgcctgggcc tggagctggg caaggtggtc acgaagaagt
181 tcagcaacca ggagaccagc gtggagattg gtgaaagcgt gagaggggaa gatgtctaca
241 tcatccagag cggctgcggg gaaattaacg acaacctgat ggaactcctc atcatgatca
301 atgcctgcaa gattgcgtca tcatccagag taactgccgt gatcccgtgt ttcccatacg
361 cccgacaaga taaaaaggac aagagtcgtg ccccaatttc tgcaaaactt gtggccaata
421 tgctgtcggt ggctggggcg gatcacatca tcaccatgga cctgcatgct tctcagatac
481 agggattctt tgatattcct gtggataatt tgtatgcgga gcccgcagtc ctgcagtgga
541 ttcgggaaaa cattgccgag tggaagaact gtatcattgt ttcacctgac gcagggggag
601 ccaaaagggt tacatcaatt gcagacaggt tgaatgtgga atttgctttg atccacaaag
661 agaggaagaa ggcgaatgaa gtggaccgga tggtcctggt gggcgacgtg aaggaccgtg
721 tggccatcct cgtggatgac atggctgaca cttgcggcac catctgccat gctgcggaca
781 agctgctgtc agctggagcc accaaagtgt atgctatcct tacccatggg atcttctctg
841 gaccagctat ttccagaata aataatgccg cctttgaggc tgttgtcgtc acaaacacaa
901 ttccgcaaga ggacaaaatg aaacactgca ccaagattca ggtcattgac atttccatga
961 tcttggccga agcaatccga aggacacaca atggggaatc cgtgtcctac ctgttcagcc
1021 atgtcccgct ataaatccag aatgggaagt gtccagcaag cctactctga cttctgactt
1081 gtttttgttt tctggatttt tagctgtagg tattcagcaa tgataggtta atcactggca
1141 aaagcatcag atctttgtat atgctaagat ttattgtttc cccttctaaa gctcaagatc
1201 atttctttcc agtttttggg gaaatggtgg tggttatttg gtctttaagt gaactgtctt
1261 aaatgagaaa cgtttttgtc attttgactt ttaacaggta caggtgatct cttcctttgt
1321 tctttcagta ctttgaggcg acaactttca agtatataat ttcattgtgg aagtcatagt
1381 ttatatattt cgaggttgcc aaaggtgact tcagattaaa gccttctgtg taaatatata
1441 ctgataatgc ctatggacat ttgggtaaaa ccctgtatag aattaattat ccttttactt
1501 tggagtgaac cttggaaaat ttataattat aataccatgg attttgaatt ttcctttttt
1561 tttttttttt ggataactca gtttcagata aaccatcttg gttactgtgc ttaatttgga
1621 ccaaatttta tttagcttaa tatggacact gacacatttt ggggggtata cattagacat
1681 atcagagcag tgtatttctg gatcattttt taaatgacct cttctaaaac ataactgtca
1741 cttacctgaa atgctgcatc ctaaaattcc aaaattatat tgagcaatcg ccaaggccta
1801 aagccaactg acttaaaggt aatcatttca gctaagatta aatttaaagc ctaagaatgt
1861 atagagctag ttttaaaata atgatctcag atttttaaaa aggatatagg aacctgcatt
1921 gtcattctct gaattaagaa ctgatggttt ctatcattat ttagccccac ctttgtattt
1981 taaaatcctt cagaatacat ttatgaacca atgcgactgg acttagccac acacaatgga
2041 aattcagacc ttgactattt ggtgtttcca gttcacaaag gtgatgaaga ctgtcttggg
2101 agcagcttaa tcccaaaatt tgtacatttc ttgctgctcc tggcgtggaa acttaagtga
2161 gaccaccaaa tacattggtc ctgtccaatt ctactgaatg ggggtggact tggcatttat
2221 ctggccaaaa acaggagcca gagaaatatg aatataccaa agttgtttgt ttagcctcca
2281 acttaaatta cattagtcaa cttatagata ctcatatgat cacttttctt tttagatact
2341 acatcaacta gattcaggag tatatcattt gcagtgcttg tattggttta aaatgtaaga
2401 ttttaagatc ctctaacact gtactaaaac atttcaataa aatcattctg actgcgttaa
2461 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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