LOCUS BC110572 2777 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens potassium voltage-gated channel, Shab-related
subfamily, member 1, mRNA (cDNA clone IMAGE:40001933), partial cds.
ACCESSION BC110572
VERSION BC110572.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2777)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2777)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 8 Row: b Column: 11.
FEATURES Location/Qualifiers
source 1..2777
/db_xref="H-InvDB:HIT000339611"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:40001933"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_282"
/note="Vector: pCR-Blunt II-TOPO; Clone identification
sequence tag: ACTCTATA sequenced from the reverse primer"
gene <1..2777
/gene="KCNB1"
/gene_synonym="DRK1"
/gene_synonym="h-DRK1"
/gene_synonym="KV2.1"
/db_xref="GeneID:3745"
/db_xref="HGNC:HGNC:6231"
/db_xref="MIM:600397"
CDS <1..2442
/gene="KCNB1"
/gene_synonym="DRK1"
/gene_synonym="h-DRK1"
/gene_synonym="KV2.1"
/codon_start=1
/product="KCNB1 protein"
/protein_id="AAI10573.1"
/db_xref="GeneID:3745"
/db_xref="HGNC:HGNC:6231"
/db_xref="MIM:600397"
/translation="RDGGEKTAVTRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHP
GAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEE
LKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVLSTIA
LSLNTLPELQSLDEFGQSTDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWKFFKGPLN
AIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLG
FTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMTTVG
YGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALE
RAKRNGSIVSMNMKDAFARSIEMMDIVVEKNGENMGKKDKVQDNHLSPNKWKWTKRTL
SETSSSKSFETKEQGSPEKARSSSSPQHLNVQQLEDMYNKMAKTQSQPILNTKESAAQ
SKPKEELEMESIPSPVAPLPTRTEGVIDMRSMSSIDSFISCATDFPEATRFSHSPLTS
LPSKSGGSTAPEVGWRGALGASGGRFVEANPSPDASQHSSFFIESPKSSMKTNNPLKL
RALKVNFMEGDPSPLLPVLGMYHDPLRNRGSAAAAVAGLECATLLDKAVLSPESSIYT
TASAKTPPRSPEKHTAIAFNFEAGVHQYIDADTDDEGQLLYSVDSSPPKSLPGSTSPK
FSTGTRSEKNHFESSPLPTSPKFLRQNCIYSTEALTGKGPSGQEKCKLENHISPDVRV
LPGGGAHGSTRDQNI"
BASE COUNT 717 a 795 c 701 g 564 t
ORIGIN
1 cgggatggag gtgagaagac ggccgtgacg cggctgggca agctccgcga ctgcaacacg
61 cacgactcgc tgctcgaggt gtgcgatgac tacagcctcg acgacaacga gtacttcttt
121 gaccgccacc cgggcgcctt cacctccatc ctcaacttct accgcactgg gcgactgcac
181 atgatggagg agatgtgcgc gctcagcttc agccaagagc tcgactactg gggcatcgac
241 gagatctacc tggagtcctg ctgccaggcc cgctaccacc agaagaaaga gcagatgaac
301 gaggagctca agcgtgaggc cgagacccta cgggagcggg aaggcgagga gttcgataac
361 acgtgctgcg cagagaagag gaaaaaactc tgggacctac tggagaagcc caattcctct
421 gtggctgcca agatccttgc cataatttcc atcatgttca tcgtcctctc caccattgcc
481 ctgtccctca acacgctgcc tgagctacag agcctcgatg agttcggcca gtccacagac
541 aacccccagc tggcccacgt ggaggccgtg tgcatcgcat ggttcaccat ggagtacctg
601 ctgaggttcc tctcctcgcc caagaagtgg aagttcttca agggcccact caatgccatt
661 gacttgttgg ccattctgcc atactatgtc accattttcc tcaccgaatc caacaagagc
721 gtgctgcaat tccagaatgt ccgccgcgtg gtccagatct tccgcatcat gcgaattctc
781 cgcatcctta agcttgcacg ccactccact ggcctccagt ctctgggctt cactttgcgg
841 aggagctaca atgagttggg cttgctcatc ctcttccttg ccatgggcat tatgatcttc
901 tccagccttg tcttctttgc tgagaaggat gaggacgaca ccaagttcaa aagcatccca
961 gcctctttct ggtgggccac catcaccatg actactgttg ggtatggaga catctacccc
1021 aagactctcc tggggaaaat tgttggggga ctctgctgca ttgcaggagt cctggtgatt
1081 gctcttccca tccccatcat cgtcaataac ttctctgagt tctataagga gcagaagaga
1141 caggagaaag caatcaaacg gcgagaggct ctggagagag ccaagaggaa tggcagcatc
1201 gtatccatga acatgaagga tgcttttgcc cggagcattg agatgatgga cattgtggtt
1261 gagaaaaatg gggagaatat gggtaagaaa gacaaagtac aagataacca cttgtctcct
1321 aacaaatgga aatggacaaa gaggacactg tctgaaacca gctcaagtaa gtcctttgaa
1381 accaaggaac agggatcccc tgaaaaagcc agatcgtctt ctagtcctca gcacctgaac
1441 gttcagcagt tggaagacat gtacaataag atggccaaga cccaatccca acccatcctc
1501 aataccaagg agtcagcagc acagagcaaa ccaaaggaag aacttgaaat ggagagtatc
1561 cccagccccg tagcccctct gcccactcgc acagaagggg tcattgacat gcgaagtatg
1621 tcaagcattg atagtttcat tagctgtgcc acagacttcc ctgaggccac cagattctcc
1681 cacagccctt tgacatcact ccccagcaag agtgggggca gcacagcccc agaagtgggc
1741 tggcggggag ctctgggtgc cagtggtggt aggtttgtgg aggccaaccc cagccctgat
1801 gccagccagc actctagttt cttcatcgag agccccaaga gttccatgaa aactaacaac
1861 cctttgaagc tccgagcact taaagtcaac ttcatggagg gtgaccccag tccactcctc
1921 cccgttctag ggatgtacca tgaccctctc aggaaccggg ggagtgctgc ggctgctgtc
1981 gctggactgg agtgtgccac gcttttggac aaggctgtgc tgagcccaga gtcctccatc
2041 tacaccacag caagtgctaa gacacccccc cggtctcctg agaaacacac agcaatagcg
2101 ttcaactttg aggcgggtgt ccaccagtac attgacgcag acacagatga tgagggacag
2161 ctgctctaca gtgtggactc cagccccccc aaaagcctcc ctgggagcac cagtccgaag
2221 ttcagcacgg ggacaagatc ggagaaaaac cactttgaaa gctccccttt acccacctcc
2281 cctaagttct taaggcagaa ctgtatttac tccacagaag cattgactgg aaaaggcccc
2341 agtggtcagg aaaagtgcaa acttgagaac cacatctccc ctgacgtccg tgtgttgcca
2401 gggggaggag cccatggaag cacacgagat cagaacatct gaactgccct gccttggagg
2461 agagactttt gggtgaggtc caaagaggag agctgttcag cttacctgcc acagagcttt
2521 tctgcatgaa ctctggaaca gaaaggccct gtaaagccct cagagagaag agagactcca
2581 gagaaggctc cctaagacct tgagagccat gacaggtcca tcagcatgaa gttggccaag
2641 ccatagggca cagcacctcc ttgtaacaac tctatagccc tctttgggag atgacatgag
2701 tggaactcac agccaccact accaccactt tagacaggac cgaggccaca tactccccat
2761 tctctcgtgg ctttcca
//