LOCUS BC110351 2460 bp mRNA linear HUM 17-NOV-2006
DEFINITION Homo sapiens potassium voltage-gated channel, shaker-related
subfamily, beta member 2, mRNA (cDNA clone MGC:117289
IMAGE:5214271), complete cds.
ACCESSION BC110351
VERSION BC110351.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2460)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2460)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (18-NOV-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 233 Row: e Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27436967.
FEATURES Location/Qualifiers
source 1..2460
/db_xref="H-InvDB:HIT000339517"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:117289 IMAGE:5214271"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2460
/gene="KCNAB2"
/gene_synonym="AKR6A5"
/gene_synonym="HKvbeta2"
/gene_synonym="HKvbeta2.1"
/gene_synonym="HKvbeta2.2"
/gene_synonym="KCNA2B"
/gene_synonym="KV-BETA-2"
/db_xref="GeneID:8514"
/db_xref="HGNC:HGNC:6229"
/db_xref="MIM:601142"
CDS 179..1366
/gene="KCNAB2"
/gene_synonym="AKR6A5"
/gene_synonym="HKvbeta2"
/gene_synonym="HKvbeta2.1"
/gene_synonym="HKvbeta2.2"
/gene_synonym="KCNA2B"
/gene_synonym="KV-BETA-2"
/codon_start=1
/product="KCNAB2 protein"
/protein_id="AAI10352.1"
/db_xref="GeneID:8514"
/db_xref="HGNC:HGNC:6229"
/db_xref="MIM:601142"
/translation="MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGK
SGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNI
IKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP
DPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYH
MFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDK
ILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENI
GAIQVRVRGPAGQRAHPSPSPVQCILPGSSCVPGSVLGTQDAPVNHQSCAPGELAFQQ
EQT"
BASE COUNT 597 a 637 c 774 g 452 t
ORIGIN
1 gctgcaccaa cttcctgttg ggtgctgtgg tcccaaggcg cgtgctttgc agcagatgtg
61 tgacctggcg ttcccctgag tgctcggaaa atggccttgt ctccggtcgt tcccgttcag
121 gagcagaatt ttcccactgt aaaaaaccga gcaagtctgg ataagtgagg ctggctccat
181 gtatccagaa tcaacgacgg gctccccggc tcggctctcg ctgcggcaga cgggctcccc
241 cgggatgatc tacagtactc ggtatgggag tcccaaaaga cagctccagt tttacaggaa
301 cctgggcaag tctggcctgc gggtctcctg cctgggactt ggaacatggg tgaccttcgg
361 aggccagatc accgatgaga tggcagagca gctcatgacc ttggcctatg ataatggcat
421 caacctcttc gatacagcag aagtctacgc agccggcaag gctgaagtgg tactgggaaa
481 catcattaag aagaaaggat ggaggcggtc cagcctcgtc atcaccacca agatcttctg
541 gggcggaaag gcggagacgg agcggggcct gtccaggaag cacataatcg aaggtctgaa
601 agcttccctg gagcgactgc agctggagta cgtggatgtg gtgtttgcca accgcccgga
661 ccccaacacc ccgatggaag agaccgtccg cgccatgacc cacgtcatca accaggggat
721 ggccatgtac tggggcacgt cacgctggag ctccatggag atcatggagg cctactccgt
781 ggcccggcag ttcaacctga ccccgcccat ctgcgagcag gctgagtacc acatgttcca
841 gcgtgagaaa gtggaggtgc agctgccgga gctgttccac aagataggag tgggcgccat
901 gacctggtcc cctctggcct gtggcattgt ttctggcaag tacgacagtg gcatcccacc
961 ctactcaaga gcctccttga agggctacca gtggctgaag gacaagatcc tcagtgagga
1021 gggccggcgc cagcaagcca agctgaagga gctgcaggcc atcgccgagc gcctgggctg
1081 caccctgccc cagctggcca tagcctggtg cctgaggaat gagggagtca gctccgtgct
1141 cctgggggcc tccaatgcgg accagctcat ggagaacatt ggggcaatac aggtaagagt
1201 gagaggccct gctgggcaga gggcccatcc cagcccgagc cccgtccagt gcatcctccc
1261 aggctcgtcc tgcgtgccag gctctgttct aggcactcag gatgcgcccg tgaaccatca
1321 gagttgtgct cctggagagc ttgctttcca gcaggaacag acatgaacac taactgcacg
1381 aaacaaggag gttagaatgt gtgtcagggt ggacgagcgc tgtaggagag aagccagaga
1441 taaagggagg gagctggggc cagggacggt ggcgctgcag actcaggttc aagggggcct
1501 gtcaggtggg cttgttgaga aggtggtgct tgagcagtct tgagagatgc ggagtaagtc
1561 acgcaaatgc ctgcgggaag aaccttccac cagcaggaag agttgatgca aaggcccaaa
1621 aaggcctgga gcagaggggc agatcctgag aggcacgaaa cacctccagg gacttctgag
1681 tgagacggga gccgtggcaa aattgtgggc agaggagggc gagctgcagc tcagcctgga
1741 aagggaggct gctctccggc tgctccatcg gggaggcttt gggaagcaaa agtcgaagca
1801 gagagccctg gtgggaagtg gcagctgcgg gtccgagacg ggagtggtgg ttggatcctg
1861 gatgtttggg aaggtggggc ccccgggact ggctgacaaa ctggatgtgg gggtgagaag
1921 gcgaggtgga agtcggtccc cgggtgtgtc acccggaagg gtggcggtgc tgtatgctga
1981 ggcaggcgca gctggaaaaa gcagtcacgg acatggaagt ccagcatttg gcctggagtt
2041 tccattttat gtcactgctg ccaccaccct tcaggaaggt tctagggcac cttgacattt
2101 gagagggagt gcacagaccc aggcatgctt cctctctgcc ccaaaccttc tgaaacacaa
2161 aagcagcgtg gcctccatct gcctcagatg gagcccagat gtgatggggc aacccgggcc
2221 tggccagccg accatctgga agagcctggc cccacctcct ccccaggcca ggcccgtctt
2281 gttggtggga ttctgatttg ttgttgttct tgcacgcagg tccttccgaa actgtcatct
2341 tccattatcc acgagattga tagtattttg ggcaataaac cctacagcaa aaaggaaaaa
2401 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//