LOCUS BC110338 1985 bp mRNA linear HUM 24-JUL-2006
DEFINITION Homo sapiens carboxylesterase 1 (monocyte/macrophage serine
esterase 1), mRNA (cDNA clone MGC:117365 IMAGE:5756350), complete
cds.
ACCESSION BC110338
VERSION BC110338.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1985)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1985)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (18-NOV-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 233 Row: o Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 7706474.
FEATURES Location/Qualifiers
source 1..1985
/db_xref="H-InvDB:HIT000339505"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:117365 IMAGE:5756350"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1985
/gene="CES1"
/gene_synonym="ACAT"
/gene_synonym="CEH"
/gene_synonym="CES1A1"
/gene_synonym="CES1A1a"
/gene_synonym="CES1A1b"
/gene_synonym="CES1A1c"
/gene_synonym="CES1A2"
/gene_synonym="CES2"
/gene_synonym="HMSE"
/gene_synonym="HMSE1"
/gene_synonym="SES1"
/gene_synonym="TGH"
/db_xref="GeneID:1066"
/db_xref="HGNC:HGNC:1863"
/db_xref="MIM:114835"
CDS 51..1754
/gene="CES1"
/gene_synonym="ACAT"
/gene_synonym="CEH"
/gene_synonym="CES1A1"
/gene_synonym="CES1A1a"
/gene_synonym="CES1A1b"
/gene_synonym="CES1A1c"
/gene_synonym="CES1A2"
/gene_synonym="CES2"
/gene_synonym="HMSE"
/gene_synonym="HMSE1"
/gene_synonym="SES1"
/gene_synonym="TGH"
/codon_start=1
/product="carboxylesterase 1 (monocyte/macrophage serine
esterase 1)"
/protein_id="AAI10339.1"
/db_xref="GeneID:1066"
/db_xref="HGNC:HGNC:1863"
/db_xref="MIM:114835"
/translation="MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFA
QPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFT
NRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAH
ENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIF
GESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKT
TTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEE
LQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIA
KELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQ
YRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGN
PNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIE
L"
BASE COUNT 510 a 486 c 548 g 441 t
ORIGIN
1 ctgaactgca cagagacctc gcaggccccg agaactgtcg cccttccacg atgtggctcc
61 gtgcctttat cctggccact ctctctgctt ccgcggcttg ggggcatccg tcctcgccac
121 ctgtggtgga caccgtgcat ggcaaagtgc tggggaagtt cgtcagctta gaaggatttg
181 cacagcctgt ggccattttc ctgggaatcc cttttgccaa gccgcctctt ggacccctga
241 ggtttactcc accgcagcct gcagaaccat ggagctttgt gaagaatgcc acctcgtacc
301 ctcctatgtg cacccaagat cccaaggcgg ggcagttact ctcagagcta tttacaaacc
361 gaaaggagaa cattcctctc aagctttctg aagactgtct ttacctcaat atttacactc
421 ctgctgactt gaccaagaaa aacaggctgc cggtgatggt gtggatccac ggaggggggc
481 tgatggtggg tgcggcatca acctatgatg ggctggccct tgctgcccat gaaaacgtgg
541 tggtggtgac cattcaatat cgcctgggca tctggggatt cttcagcaca ggggatgaac
601 acagccgggg gaactggggt cacctggacc aggtggctgc cctgcgctgg gtccaggaca
661 acattgccag ctttggaggg aacccaggct ctgtgaccat ctttggagag tcagcgggag
721 gagaaagtgt ctctgttctt gttttgtctc cattggccaa gaacctcttc caccgggcca
781 tttctgagag tggcgtggcc ctcacttctg ttctggtgaa gaaaggtgat gtcaagccct
841 tggctgagca aattgctatc actgctgggt gcaaaaccac cacctctgct gtcatggttc
901 actgcctgcg acagaagacg gaagaggagc tcttggagac gacattgaaa atgaaattct
961 tatctctgga cttacaggga gaccccagag agagtcaacc ccttctgggc actgtgattg
1021 atgggatgct gctgctgaaa acacctgaag agcttcaagc tgaaaggaat ttccacactg
1081 tcccctacat ggtcggaatt aacaagcagg agtttggctg gttgattcca atgcagttga
1141 tgagctatcc actctccgaa gggcaactgg accagaagac agccatgtca ctcctgtgga
1201 agtcctatcc ccttgtttgc attgctaagg aactgattcc agaagccact gagaaatact
1261 taggaggaac agacgacact gtcaaaaaga aagacctgtt cctggacttg atagcagatg
1321 tgatgtttgg tgtcccatct gtgattgtgg cccggaacca cagagatgct ggagcaccca
1381 cctacatgta tgagtttcag taccgtccaa gcttctcatc agacatgaaa cccaagacgg
1441 tgataggaga ccacggggat gagctcttct ccgtctttgg ggccccattt ttaaaagagg
1501 gtgcctcaga agaggagatc agacttagca agatggtgat gaaattctgg gccaactttg
1561 ctcgcaatgg aaaccccaat ggggaagggc tgccccactg gccagagtac aaccagaagg
1621 aagggtatct gcagattggt gccaacaccc aggcggccca gaagctgaag gacaaagaag
1681 tagctttctg gaccaacctc tttgccaaga aggcagtgga gaagccaccc cagacagaac
1741 acatagagct gtgaatgaag atccagccgg ccttgggagc ctggaggagc aaagactggg
1801 gtcttttgcg aaagggattg caggttcaga aggcatctta ccatggctgg ggaattgtct
1861 ggtggtgggg ggcaggggac agaggccatg aaggagcaag ttttgtattt gtgacctcag
1921 ctttgggaat aaaggatctt ttgaaggcca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1981 aaaaa
//