LOCUS BC107748 868 bp mRNA linear HUM 21-JUL-2006
DEFINITION Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho
family, small GTP binding protein Rac1), mRNA (cDNA clone
MGC:111543 IMAGE:6699945), complete cds.
ACCESSION BC107748
VERSION BC107748.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 868)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 868)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-OCT-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: NCI
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 61 Row: m Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38505163.
FEATURES Location/Qualifiers
source 1..868
/db_xref="H-InvDB:HIT000338878"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:111543 IMAGE:6699945"
/tissue_type="Pooled, 40 cell lines"
/clone_lib="NIH_MGC_128"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..868
/gene="RAC1"
/gene_synonym="MIG5"
/gene_synonym="p21-Rac1"
/gene_synonym="TC-25"
/db_xref="GeneID:5879"
/db_xref="HGNC:HGNC:9801"
/db_xref="MIM:602048"
CDS 204..782
/gene="RAC1"
/gene_synonym="MIG5"
/gene_synonym="p21-Rac1"
/gene_synonym="TC-25"
/codon_start=1
/product="ras-related C3 botulinum toxin substrate 1 (rho
family, small GTP binding protein Rac1)"
/protein_id="AAI07749.1"
/db_xref="GeneID:5879"
/db_xref="HGNC:HGNC:9801"
/db_xref="MIM:602048"
/translation="MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANV
MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVR
HHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSAL
TQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL"
BASE COUNT 212 a 241 c 229 g 186 t
ORIGIN
1 gggggcagtt ttcctcagct ttgggtggtg gccgctgccg ggcatcggct tccagtccgc
61 ggagggcgag gcggcgtgga cagcggcccc ggcacccagc gccccgccgc ccgcaagccg
121 cgcgcccgtc cgccgcgccc cgagcccgcc gcttcctatc tcagcgccct gccgccgccg
181 ccgcggccca gcgagcggcc ctgatgcagg ccatcaagtg tgtggtggtg ggagacggag
241 ctgtaggtaa aacttgccta ctgatcagtt acacaaccaa tgcatttcct ggagaatata
301 tccctactgt ctttgacaat tattctgcca atgttatggt agatggaaaa ccggtgaatc
361 tgggcttatg ggatacagct ggacaagaag attatgacag attacgcccc ctatcctatc
421 cgcaaacaga tgtgttctta atttgctttt cccttgtgag tcctgcatca tttgaaaatg
481 tccgtgcaaa gtggtatcct gaggtgcggc accactgtcc caacactccc atcatcctag
541 tgggaactaa acttgatctt agggatgata aagacacgat cgagaaactg aaggagaaga
601 agctgactcc catcacctat ccgcagggtc tagccatggc taaggagatt ggtgctgtaa
661 aatacctgga gtgctcggcg ctcacacagc gaggcctcaa gacagtgttt gacgaagcga
721 tccgagcagt cctctgcccg cctcccgtga agaagaggaa gagaaaatgc ctgctgttgt
781 aaatgtctca gcccctcgtt cttggtcctg tcccttggaa cctttgtacg ctttgcacaa
841 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//