LOCUS BC106740 1139 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens tryptophan hydroxylase 1, mRNA (cDNA clone
IMAGE:40016889), complete cds.
ACCESSION BC106740
VERSION BC106740.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1139)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1139)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 4, 2006 this sequence version replaced BC106740.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 13 Row: a Column: 4
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1139
/db_xref="H-InvDB:HIT000338483"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:40016889"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: CACATTC sequenced from
the forward primer"
gene 1..1139
/gene="TPH1"
/db_xref="GeneID:7166"
/db_xref="HGNC:HGNC:12008"
/db_xref="MIM:191060"
CDS 1..621
/gene="TPH1"
/codon_start=1
/product="TPH1 protein"
/protein_id="AAI06741.1"
/db_xref="GeneID:7166"
/db_xref="HGNC:HGNC:12008"
/db_xref="MIM:191060"
/translation="MIEDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVN
LLHIESRKSKRRNSEFEIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLNEDGM
ETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKQAYR
FFHPSCGWLLITKRFLIRFSLSSFSLHSICETQFRSLLYPRARYLP"
BASE COUNT 345 a 228 c 235 g 331 t
ORIGIN
1 atgattgaag acaataagga gaacaaagac cattccttag aaaggggaag agcaagtctc
61 attttttcct taaagaatga agttggagga cttataaaag ccctgaaaat ctttcaggag
121 aagcatgtga atctgttaca tatcgagtcc cgaaaatcaa aaagaagaaa ctcagaattt
181 gagatttttg ttgactgtga catcaacaga gaacaattga atgatatttt tcatctgctg
241 aagtctcata ccaatgttct ctctgtgaat ctaccagata attttacttt gaatgaagat
301 ggtatggaaa ctgttccttg gtttccaaag aagatttctg acctggacca ttgtgccaac
361 agagttctga tgtatggatc tgaactagat gcagaccatc ctggcttcaa agacaatgtc
421 taccgtaaac gtcgaaagta ttttgcggac ttggctatga actataaaca agcgtacagg
481 tttttccatc cgtcctgtgg ctggttactt atcaccaaga gatttcttat caggtttagc
541 ctttcgagtt tttcactgca ctcaatatgt gagacacagt tcagatccct tctatacccc
601 agagccagat acctgccatg aactcttagg tcatgtcccg cttttggctg aacctagttt
661 tgcccaattc tcccaagaaa ttggcttggc ttctcttggc gcttcagagg aggctgttca
721 aaaactggca acgtgctact ttttcactgt ggagtttggt ctatgtaaac aagatggaca
781 gctaagagtc tttggtgctg gcttactttc ttctatcagt gaactcaaac atgcactttc
841 tggacatgcc aaagtaaagc cctttgatcc caagattacc tgcaaacagg aatgtcttat
901 cacaactttt caagatgtct actttgtatc tgaaagtttt gaagatgcaa aggagaagat
961 gagagaattt accaaaacaa ttaagcgtcc atttggagtg aagtataatc catatacacg
1021 gagtattcag atcctgaaag acaccaagag cataaccagt gccatgaatg agctgcagca
1081 tgatctcgat gttgtcagtg atgcccttgc taaggtcagc aggaagccga gtatctaaa
//