LOCUS BC106007 1735 bp mRNA linear HUM 03-NOV-2005
DEFINITION Homo sapiens single immunoglobulin and toll-interleukin 1 receptor
(TIR) domain, mRNA (cDNA clone MGC:110992 IMAGE:6092503), complete
cds.
ACCESSION BC106007
VERSION BC106007.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1735)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1735)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 232 Row: d Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 11141876.
FEATURES Location/Qualifiers
source 1..1735
/db_xref="H-InvDB:HIT000338373"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:110992 IMAGE:6092503"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_70"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1735
/gene="SIGIRR"
/gene_synonym="TIR8"
/db_xref="GeneID:59307"
/db_xref="HGNC:HGNC:30575"
/db_xref="IMGT/GENE-DB:30575"
/db_xref="MIM:605478"
CDS 308..1540
/gene="SIGIRR"
/gene_synonym="TIR8"
/codon_start=1
/product="SIGIRR protein"
/protein_id="AAI06008.1"
/db_xref="GeneID:59307"
/db_xref="HGNC:HGNC:30575"
/db_xref="IMGT/GENE-DB:30575"
/db_xref="MIM:605478"
/translation="MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSL
PSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQN
ISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEIN
DGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNL
SRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLL
RQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVRYRPVEGDPQTQLQDDKDPMLIL
RGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVSDLGS
RNYSARTDFYCLVSKDDM"
BASE COUNT 320 a 572 c 529 g 314 t
ORIGIN
1 aagacacaag ccaggtcccc accgcgcttg gcgatgcatc catagcagcc ttggtgctgt
61 ggacactccc tggggcccag cgaaggggag agtttgctcc caaaggcgca ccaatgacca
121 acatttgccc cccggaggaa agaactggaa ccagcctctg acctgtccag gtgccctgtc
181 cagctgactg caaggacaga gaggagtcct gcccagctct tggatcagtc tgctggccga
241 ggagcccggt ggagccaggg gtgaccctgg agcccagcct gccccgagga ggccccggct
301 cagagccatg ccaggtgtct gtgatagggc ccctgacttc ctctccccgt ctgaagacca
361 ggtgctgagg cctgccttgg gcagctcagt ggctctgaac tgcacggctt gggtagtctc
421 tgggccccac tgctccctgc cttcagtcca gtggctgaaa gacgggcttc cattgggaat
481 tgggggccac tacagcctcc acgagtactc ctgggtcaag gccaacctgt cagaggtgct
541 tgtgtccagt gtcctggggg tcaacgtgac cagcactgaa gtctatgggg ccttcacctg
601 ctccatccag aacatcagct tctcctcctt cactcttcag agagctggcc ctacaagcca
661 cgtggctgcg gtgctggcct ccctcctggt cctgctggcc ctgctgctgg ccgccctgct
721 ctatgtcaag tgccgtctca acgtgctgct ctggtaccag gacgcgtatg gggaggtgga
781 gataaacgac gggaagctct acgacgccta cgtctcctac agcgactgcc ccgaggaccg
841 caagttcgtg aacttcatcc taaagccgca gctggagcgg cgtcggggct acaagctctt
901 cctggacgac cgcgacctcc tgccgcgcgc tgagccctcc gccgacctct tggtgaacct
961 gagccgctgc cgacgcctca tcgtggtgct ttcggacgcc ttcctgagcc gggcctggtg
1021 cagccacagc ttccgggagg gcctgtgccg gctgctggag ctcacccgca gacccatctt
1081 catcaccttc gagggccaga ggcgcgaccc cgcgcacccg gcgctccgcc tgctgcgcca
1141 gcaccgccac ctggtgacct tgctgctctg gaggcccggc tccgtgactc cttcctccga
1201 tttttggaaa gaagtgcagc tggcgctgcc gcggaaggtg cggtacaggc cggtggaagg
1261 agacccccag acgcagctgc aggacgacaa ggaccccatg ctgattcttc gaggccgagt
1321 ccctgagggc cgggccctgg actcagaggt ggacccggac cctgagggcg acctgggtgt
1381 ccgggggcct gtttttggag agccatcagc tccaccgcac accagtgggg tctcgctggg
1441 agagagccgg agcagcgaag tggacgtctc ggatctcggc tcgcgaaact acagtgcccg
1501 cacagacttc tactgcctgg tgtccaagga tgatatgtag ctcccacccc agagtgcagg
1561 atcataggga cagcgggggc cagggcagcg gcgtcgctcc tctgctcaac aggaccacaa
1621 cccctgccag cagccctggg accctgccag cagccctggg aaaaggctgt ggcctcaggg
1681 cgcctcccag tgccagaaaa taaagtcctt ttggattctg aaaaaaaaaa aaaaa
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