LOCUS BC105059 2408 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens phosphate regulating endopeptidase homolog, X-linked,
mRNA (cDNA clone MGC:132719 IMAGE:8144062), complete cds.
ACCESSION BC105059
VERSION BC105059.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2408)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2408)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 3 Row: m Column: 20.
FEATURES Location/Qualifiers
source 1..2408
/db_xref="H-InvDB:HIT000338147"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:132719 IMAGE:8144062"
/tissue_type="Brain, cerebral cortex and lung, PCR rescued
clones"
/clone_lib="NIH_MGC_323"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: GGACGTTG"
gene 1..2408
/gene="PHEX"
/gene_synonym="HPDR1"
/gene_synonym="HYP1"
/gene_synonym="PEX"
/gene_synonym="XLH"
/db_xref="GeneID:5251"
/db_xref="HGNC:HGNC:8918"
/db_xref="MIM:300550"
CDS 85..2334
/gene="PHEX"
/gene_synonym="HPDR1"
/gene_synonym="HYP1"
/gene_synonym="PEX"
/gene_synonym="XLH"
/codon_start=1
/product="phosphate regulating endopeptidase homolog,
X-linked"
/protein_id="AAI05060.1"
/db_xref="GeneID:5251"
/db_xref="HGNC:HGNC:8918"
/db_xref="MIM:300550"
/translation="MEAETGSSVETGKKANRGTRIALVVFVGGTLVLGTILFLVSQGL
LSLQAKQEYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYG
VYPWLRHNVDLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHIL
RHSPFRWPVLESNIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEH
ILKLDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLR
LEIKIAEIMIPHENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDIS
PSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRV
IQGTTTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDML
EKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQ
TRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYP
RSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSN
YYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLPGITFTNNQ
LFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMN
RGMDSCRLW"
BASE COUNT 708 a 517 c 582 g 601 t
ORIGIN
1 tggatgtcaa cgcctcgctc ttgagaccag ccaccaaacc acgaaaagtg actttcttct
61 cgtgtgctct ctacggccct tctgatggaa gcagaaacag ggagcagcgt ggagactgga
121 aagaaggcca acagaggcac tcgaattgcc ctggtcgtgt ttgtcggtgg caccctagtt
181 ctgggcacga tcctctttct agtgagtcaa ggtctcttaa gtctccaagc taaacaggag
241 tactgcctga agccagaatg catcgaagcg gctgctgcca tcttaagtaa agtaaatctg
301 tctgtggatc cttgtgataa tttcttccgg ttcgcttgtg atggctggat aagcaataat
361 ccaattcccg aagatatgcc aagctatggg gtttatcctt ggctgagaca taatgttgac
421 ctcaagttga aggaactttt ggagaaatca atcagtagaa ggcgggacac cgaagccata
481 cagaaagcca aaatccttta ttcatcctgc atgaatgaga aagcgattga aaaagcagat
541 gccaagccac tgctacacat cctacggcat tcacctttcc gctggcccgt gcttgaatct
601 aatattggcc ctgaaggggt ttggtcagag agaaagttca gccttctgca gacacttgca
661 acgtttcgtg gtcaatacag caattctgtg ttcatccgtt tgtatgtgtc ccctgatgac
721 aaagcatcca atgaacatat cttgaagctg gaccaagcaa cactctccct ggccgtgagg
781 gaagactacc ttgataacag tacagaagcc aagtcttatc gggatgccct ttacaagttc
841 atggtggata ctgccgtgct tttaggagct aacagttcca gagcagagca tgacatgaag
901 tcagtgctca gattggaaat taagatagct gagataatga ttccacatga aaaccgaacc
961 agcgaggcca tgtacaacaa aatgaacatt tctgaactga gtgctatgat tccccagttc
1021 gactggctgg gctacatcaa gaaggtcatt gacaccagac tctaccccca tctgaaagac
1081 atcagcccct ccgagaatgt ggtggtccgc gtcccgcagt actttaaaga tttgtttagg
1141 atattagggt ctgagagaaa gaagaccatt gccaactatt tggtgtggag aatggtttat
1201 tccagaattc caaaccttag caggcgcttt cagtatagat ggctggaatt ctcaagggta
1261 atccagggga ccacaacttt gctgcctcaa tgggacaaat gtgtaaactt tattgaaagt
1321 gccctccctt atgttgttgg aaagatgttt gtagatgtgt acttccagga agataagaag
1381 gaaatgatgg aggaattggt tgagggcgtt cgctgggcct ttattgacat gctagagaaa
1441 gaaaatgagt ggatggatgc aggaacgaaa aggaaagcca aagaaaaggc gagagctgtt
1501 ttggcaaaag ttggctatcc agagtttata atgaatgata ctcatgttaa tgaagacctc
1561 aaagctatca agttttcaga agccgactac tttggcaacg tcctacaaac tcgcaagtat
1621 ttagcacagt ctgatttctt ctggctaaga aaagccgttc caaaaacaga gtggtttaca
1681 aatccgacga ctgtcaatgc cttctacagt gcatccacca accagatccg atttccagca
1741 ggagagctcc agaagccttt cttttgggga acagaatatc ctcgatctct gagttatggt
1801 gctataggag taattgtcgg acatgaattt acacatggat ttgataataa tggtagaaaa
1861 tatgataaaa atggaaacct ggatccttgg tggtctactg aatcagaaga aaagtttaag
1921 gaaaaaacaa aatgcatgat taaccagtat agcaactatt attggaagaa agctggctta
1981 aatgtcaagg ggaagaggac cctgggagaa aatattgctg ataatggagg cctgcgggaa
2041 gcttttaggg cttacaggaa atggataaat gacagaaggc agggacttga ggagcctctt
2101 ctaccaggca tcacattcac caacaaccag ctcttcttcc tgagttatgc tcatgtgagg
2161 tgcaattcct acagaccaga agctgcccga gaacaagtcc aaattggtgc tcacagtccc
2221 cctcagttta gggtcaatgg tgcaattagt aactttgaag aattccagaa agcttttaac
2281 tgtccaccca attccacgat gaacagaggc atggactcct gccgactctg gtagctggga
2341 cgctggttta tggcatcctg agacagttgc acagtgccag cggaggctgc actgagcctt
2401 catcgccc
//