LOCUS BC105045 1363 bp mRNA linear HUM 21-JUL-2006
DEFINITION Homo sapiens thyrotropin-releasing hormone receptor, mRNA (cDNA
clone MGC:132705 IMAGE:8144048), complete cds.
ACCESSION BC105045
VERSION BC105045.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1363)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1363)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 3 Row: m Column: 6.
FEATURES Location/Qualifiers
source 1..1363
/db_xref="H-InvDB:HIT000338133"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:132705 IMAGE:8144048"
/tissue_type="Brain, cerebral cortex and lung, PCR rescued
clones"
/clone_lib="NIH_MGC_323"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: CTTGGACT"
gene 1..1363
/gene="TRHR"
/db_xref="GeneID:7201"
/db_xref="HGNC:HGNC:12299"
/db_xref="MIM:188545"
CDS 90..1286
/gene="TRHR"
/codon_start=1
/product="thyrotropin-releasing hormone receptor"
/protein_id="AAI05046.1"
/db_xref="GeneID:7201"
/db_xref="HGNC:HGNC:12299"
/db_xref="MIM:188545"
/translation="MENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNI
MVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCIT
YLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLW
FFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARIL
FLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFA
LLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKL
CNCKQKPTEKPANYSVALNYSVIKESDHFSTELDDITVTDTYLSATKVSFDDTCLASE
VSFSQS"
BASE COUNT 382 a 316 c 278 g 387 t
ORIGIN
1 gggggatgga actgctgcaa taaaggtggg cgctggaaag aagatgtttt gagaagtcag
61 tgtttccgag aaactttaag cttctaaaga tggaaaacga gacagtcagt gaactgaacc
121 aaacacagct tcagccacga gcagtggtgg ccttagaata ccaggtggtc accatcttac
181 ttgtactcat tatttgtggc ctgggcattg taggcaacat catggtagtc ctggttgtca
241 tgagaaccaa gcacatgagg acccccacaa actgctacct ggtgagcctg gcagtagctg
301 atctcatggt cttggtggcc gcaggcctcc ccaacataac agacagtatc tacggttcct
361 gggtctatgg ctatgttgga tgcctctgca ttacttacct ccagtatttg ggaattaatg
421 catcctcttg ttcaataaca gcctttacca ttgagaggta catagcaatc tgtcacccca
481 tcaaagccca gtttctctgc acattttcca gagccaaaaa gattatcatc tttgtctggg
541 ctttcacatc tctttactgt atgctctggt tcttcttgct ggatctcaat attagcacct
601 acaaagatgc tattgtgata tcctgtggct acaagatctc caggaattac tactcaccta
661 tttacctaat ggactttggt gtcttttatg ttgtgccaat gatcctggct accgtcctct
721 atggattcat agctagaatc cttttcttaa atcccattcc ttcagatcct aaagaaaact
781 ctaagacatg gaaaaatgat tcaacccatc agaacacaaa tctgaatgta aatacctcta
841 atagatgttt caacagcaca gtatcttcaa ggaagcaggt caccaagatg ctggcagtgg
901 ttgtaattct gtttgccctt ttatggatgc cctacaggac tctagtggtt gtcaactcat
961 ttctctccag tcctttccaa gaaaattggt ttttgctctt ttgcagaatt tgcatttatc
1021 tcaacagtgc catcaacccg gtgatttaca atctcatgtc ccagaaattc cgtgcagcct
1081 tcagaaagct ctgcaactgc aagcagaagc caacagagaa acctgctaac tacagtgtgg
1141 ccctaaatta cagcgtcatc aaggagtcag accatttcag cacagagctt gatgatatca
1201 ctgtcactga cacttacctg tctgccacaa aagtgtcttt tgatgacacc tgcttggctt
1261 ctgaggtatc ctttagccaa agttgattca tgaattagaa gaaaatggat gacaaagaaa
1321 atgagaatct gtgcagtcat caacaaaagg gagaacatgg cca
//