LOCUS BC104844 2656 bp mRNA linear HUM 21-JUL-2006
DEFINITION Homo sapiens T-box, brain, 1, mRNA (cDNA clone MGC:132504
IMAGE:8143847), complete cds.
ACCESSION BC104844
VERSION BC104844.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2656)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2656)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 3 Row: d Column: 21.
FEATURES Location/Qualifiers
source 1..2656
/db_xref="H-InvDB:HIT000337932"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:132504 IMAGE:8143847"
/tissue_type="Brain, cerebral cortex and lung, PCR rescued
clones"
/clone_lib="NIH_MGC_322"
/note="Vector: pCR4-TOPO; Clone identification sequence
tag: CTAGGGAG"
gene 1..2656
/gene="TBR1"
/gene_synonym="TES-56"
/db_xref="GeneID:10716"
/db_xref="HGNC:HGNC:11590"
/db_xref="MIM:604616"
CDS 246..2294
/gene="TBR1"
/gene_synonym="TES-56"
/codon_start=1
/product="T-box, brain, 1"
/protein_id="AAI04845.1"
/db_xref="GeneID:10716"
/db_xref="HGNC:HGNC:11590"
/db_xref="MIM:604616"
/translation="MQLEHCLSPSIMLSKKFLNVSSSYPHSGGSELVLHDHPIISTTD
NLERSSPLKKITRGMTNQSDTDNFPDSKDSPGDVQRSKLSPVLDGVSELRHSFDGSAA
DRYLLSQSSQPQSAATAPSAMFPYPGQHGPAHPAFSIGSPSRYMAHHPVITNGAYNSL
LSNSSPQGYPTAGYPYPQQYGHSYQGAPFYQFSSTQPGLVPGKAQVYLCNRPLWLKFH
RHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHWRFQGGKWVPCGK
ADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQMVVLQSLHKYQ
PRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPFAKGFR
DNYDTIYTGCDMDRLTPSPNDSPRSQIVPGARYAMAGSFLQDQFVSNYAKARFHPGAG
AGPGPGTDRSVPHTNGLLSPQQAEDPGAPSPQRWFVTPANNRLDFAASAYDTATDFAG
NAATLLSYAAAGVKALPLQAAGCTGRPLGYYADPSGWGARSPPQYCGTKSGSVLPCWP
NSAAAAARMAGANPYLGEEAEGLAAERSPLPPGAAEDAKPKDLSDSSWIETPSSIKSI
DSSDSGIYEQAKRRRISPADTPVSESSSPLKSEVLAQRDCEKNCAKDISGYYGFYSHS
"
BASE COUNT 550 a 877 c 681 g 548 t
ORIGIN
1 tggcaggagc cgtttcatcg gctgcacaag cagcaagatc aaaagtgagc cttttctgat
61 tgctgcatag tgtcaattgg ccaatctctt ctcccaggga aaaaaaaaag taaatcaaac
121 ctttgagaag catttgctgg ttgaagtgct ttctgtctag tgagggggtc tgtggatttc
181 tagtttatga taaataggac tttaaaaacc agggacggga gggcgagtgt tcaggttcta
241 gagctatgca gctggagcac tgcctttctc cttctatcat gctctccaag aaatttctca
301 atgtgagcag cagctaccca cattcaggcg gatccgagct tgtcttgcac gatcatccca
361 ttatctcgac cactgacaac ctggagagaa gttcaccttt gaaaaaaatt accaggggga
421 tgacgaatca gtcagataca gacaattttc ctgactccaa ggactcacca ggggacgtcc
481 agagaagtaa actctctcct gtcttggacg gggtctctga gcttcgtcac agtttcgatg
541 gctctgctgc agatcgctac ctcctctctc agtccagcca gccacagtct gcggccactg
601 ctcccagtgc catgttcccg taccccggcc agcacggacc ggcgcacccc gccttctcca
661 tcggcagccc tagccgctac atggcccacc acccggtcat caccaacgga gcctacaaca
721 gcctcctgtc caactcctcg ccgcagggat accccacggc cggctacccc tacccacagc
781 agtacggcca ctcctaccaa ggagctccgt tctaccagtt ctcctccacc cagccggggc
841 tggtgcccgg caaagcacag gtgtacctgt gcaacaggcc cctttggctg aaatttcacc
901 ggcaccaaac ggagatgatc atcaccaaac agggaaggcg catgtttcct tttttaagtt
961 ttaacatttc tggtctcgat cccacggctc attacaatat ttttgtggat gtgattttgg
1021 cggatcccaa tcactggagg tttcaaggag gcaaatgggt tccttgcggc aaagcggaca
1081 ccaatgtgca aggaaatcgg gtctatatgc atccggattc ccccaacact ggggctcact
1141 ggatgcgcca agaaatctct tttggaaaat taaaacttac gaacaacaaa ggagcttcaa
1201 ataacaatgg gcagatggtg gttttacagt ccttgcacaa gtaccagccc cgcctgcatg
1261 tggtggaagt gaacgaggac ggcacggagg acactagcca gcccggccgc gtgcagacgt
1321 tcactttccc tgagactcag ttcatcgccg tcaccgccta ccagaacacg gatattacac
1381 aactgaaaat agatcacaac ccttttgcaa aaggatttcg ggataattat gacacgatct
1441 acaccggctg tgacatggac cgcctgaccc cctcgcccaa cgactcgccg cgctcgcaga
1501 tcgtgcccgg ggcccgctac gccatggccg gctctttcct gcaggaccag ttcgtgagca
1561 actacgccaa ggcccgcttc cacccgggcg cgggcgcggg ccccgggccg ggtacggacc
1621 gcagcgtgcc gcacaccaac gggctgctgt cgccgcagca ggccgaggac ccgggcgcgc
1681 cctcgccgca acgctggttt gtgacgccgg ccaacaaccg gctggacttc gcggcctcgg
1741 cctatgacac ggccacggac ttcgcgggca acgcggccac gctgctctct tacgcggcgg
1801 cgggcgtgaa ggcgctgccg ctgcaggctg caggctgcac tggccgcccg ctcggctact
1861 acgccgaccc gtcgggctgg ggcgcccgca gtcccccgca gtactgcggc accaagtcgg
1921 gctcggtgct gccctgctgg cccaacagcg ccgcggccgc cgcgcgcatg gccggcgcca
1981 atccctacct gggcgaggag gccgagggcc tggccgccga gcgctcgccg ctgccgcccg
2041 gcgccgccga ggacgccaag cccaaggacc tgtccgattc cagctggatc gagacgccct
2101 cctcgatcaa gtccatcgac tccagcgact cggggattta cgagcaggcc aagcggaggc
2161 ggatctcgcc ggccgacacg cccgtgtccg agagttcgtc cccgctcaag agcgaggtgc
2221 tggcccagcg ggactgcgag aagaactgcg ccaaggacat tagcggctac tatggcttct
2281 actcgcacag ctaggccgcc cctacccgcc cggccccgcc gcggcccgga cccccagcca
2341 gcccctcaca gctcttcccc agctccgcct ccccacactc ctccttgcgc acccactcat
2401 tttatttgac cctcgatggc cgtctgcagc gaataagtgc aggtctccga gcgtgatttt
2461 aacctttttt gcacagcagt ctctgcaatt agctcaccga ccttcaactt tgctgtaaac
2521 cttttggttt tcctacttac tcttcttctg tggagttatc ctcctacaat tcccctcccc
2581 ctcgtctttc tcttacctcc tacttctctt tcttgtaatg aaactcttca cctttaggag
2641 acctgggcag tcctgt
//