LOCUS BC104189 1029 bp mRNA linear HUM 04-OCT-2006
DEFINITION Homo sapiens eukaryotic translation initiation factor 2B, subunit 1
alpha, 26kDa, mRNA (cDNA clone MGC:125869 IMAGE:40030991), complete
cds.
ACCESSION BC104189
VERSION BC104189.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1029)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1029)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-SEP-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 4, 2006 this sequence version replaced BC104189.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 13 Row: p Column: 2.
FEATURES Location/Qualifiers
source 1..1029
/db_xref="H-InvDB:HIT000337637"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:125869 IMAGE:40030991"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: NA"
gene 1..1029
/gene="EIF2B1"
/gene_synonym="EIF-2B"
/gene_synonym="EIF-2Balpha"
/gene_synonym="EIF2BA"
/db_xref="GeneID:1967"
/db_xref="HGNC:HGNC:3257"
/db_xref="MIM:606686"
CDS 11..928
/gene="EIF2B1"
/gene_synonym="EIF-2B"
/gene_synonym="EIF-2Balpha"
/gene_synonym="EIF2BA"
/codon_start=1
/product="eukaryotic translation initiation factor 2B,
subunit 1 alpha, 26kDa"
/protein_id="AAI04190.1"
/db_xref="GeneID:1967"
/db_xref="HGNC:HGNC:3257"
/db_xref="MIM:606686"
/translation="MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQG
LRANLTSAIETLCGVDSSVAVSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLR
RISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLS
GKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVC
AKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYT
APSLITLLFTDLGVLTPSAVSDELIKLYL"
BASE COUNT 275 a 244 c 264 g 246 t
ORIGIN
1 gaggacgcct atggacgaca aggagttaat tgaatacttt aagtctcaga tgaaagaaga
61 tcctgacatg gcctcagcag tggctgccat ccggacgttg ctggagttct tgaagagaga
121 taaaggggag acaatccagg gtctgagggc gaatctcacc agtgccatag aaaccctgtg
181 tggtgtggac tcctctgtgg cagtgtcctc tggcggggag ctcttcctcc gcttcatcag
241 tcttgcctcc ctggaatact ccgattactc caaatgtaaa aagatcatga ttgagcgggg
301 agaacttttt ctcaggagaa tatcactgtc aagaaacaaa attgcagatc tgtgccatac
361 tttcatcaaa gatggagcga caatattgac tcacgcctac tccagagtgg tcctgagagt
421 cctggaagca gccgtggcgg ccaagaagcg atttagtgta tacgtcacag agtcacagcc
481 tgatttgtca ggtaagaaaa tggccaaagc cctctgccac ctcaacgtcc ctgtcactgt
541 ggtgctagat gctgctgtcg gctacatcat ggagaaagca gatcttgtca tagttggtgc
601 tgaaggagtt gttgaaaacg gaggaattat taacaagatt ggaaccaacc agatggctgt
661 gtgtgccaaa gcacagaaca aacctttcta tgtggttgca gaaagtttca agtttgtccg
721 gctctttcca ctaaaccagc aagacgtccc agataagttt aagtataagg cagacactct
781 caaggtcgcg cagactggac aagacctcaa agaggagcat ccgtgggtcg actacactgc
841 cccttcctta atcactctgc tgtttacaga cctgggcgtg ctgacaccct cagcagtcag
901 cgatgagctc atcaagctct atctgtaacc tgtgagccct ttcctgccaa ggtgcagctt
961 acgtagttga ggcagggtga gtagctgctt gacaccccag tgagtcaggc caaaactgag
1021 atgtgttat
//