LOCUS BC103763 1743 bp mRNA linear HUM 21-JUL-2006
DEFINITION Homo sapiens eukaryotic translation initiation factor 2B, subunit 1
alpha, 26kDa, mRNA (cDNA clone MGC:117409 IMAGE:6148834), complete
cds.
ACCESSION BC103763
VERSION BC103763.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1743)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1743)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-SEP-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 232 Row: e Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4503502.
FEATURES Location/Qualifiers
source 1..1743
/db_xref="H-InvDB:HIT000337355"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:117409 IMAGE:6148834"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1743
/gene="EIF2B1"
/gene_synonym="EIF-2B"
/gene_synonym="EIF-2Balpha"
/gene_synonym="EIF2BA"
/db_xref="GeneID:1967"
/db_xref="HGNC:HGNC:3257"
/db_xref="MIM:606686"
CDS 82..999
/gene="EIF2B1"
/gene_synonym="EIF-2B"
/gene_synonym="EIF-2Balpha"
/gene_synonym="EIF2BA"
/codon_start=1
/product="eukaryotic translation initiation factor 2B,
subunit 1 alpha, 26kDa"
/protein_id="AAI03764.1"
/db_xref="GeneID:1967"
/db_xref="HGNC:HGNC:3257"
/db_xref="MIM:606686"
/translation="MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQG
LRANLTSAIETLCGVDSSVAVSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLR
RISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLS
GKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVC
AKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYT
APSLITLLFTDLGVLTPSAVSDELIKLYL"
BASE COUNT 501 a 408 c 411 g 423 t
ORIGIN
1 cgcaggcggc gcggccggcg gacccgttcg agacagcgcg ggcggctcgg gtcccctggg
61 gctccgcagc aggaggacgc catggacgac aaggagttaa ttgaatactt taagtctcag
121 atgaaagaag atcctgacat ggcctcagca gtggctgcca tccggacgtt gctggagttc
181 ttgaagagag ataaagggga gacaatccag ggtctgaggg cgaatctcac cagtgccata
241 gaaaccctgt gtggtgtgga ctcctctgtg gcagtgtcct ctggcgggga gctcttcctc
301 cgcttcatca gtcttgcctc cctggaatac tccgattact ccaaatgtaa aaagatcatg
361 attgagcggg gagaactttt tctcaggaga atatcactgt caagaaacaa aattgcagat
421 ctgtgccata ctttcatcaa agatggagcg acaatattga ctcacgccta ctccagagtg
481 gtcctgagag tcctggaagc agccgtggcg gccaagaagc gatttagtgt atacgtcaca
541 gagtcacagc ctgatttgtc aggtaagaaa atggccaaag ccctctgcca cctcaacgtc
601 cctgtcactg tggtgctaga tgctgctgtc ggctacatca tggagaaagc agatcttgtc
661 atagttggtg ctgaaggagt tgttgaaaac ggaggaatta ttaacaagat tggaaccaac
721 cagatggctg tgtgtgccaa agcacagaac aaacctttct atgtggttgc agaaagtttc
781 aagtttgtcc ggctctttcc actaaaccag caagacgtcc cagataagtt taagtataag
841 gcagacactc tcaaggtcgc gcagactgga caagacctca aagaggagca tccgtgggtc
901 gactacactg ccccttcctt aatcactctg ctgtttacag acctgggcgt gctgacaccc
961 tcagcagtca gcgatgagct catcaagctc tatctgtaac ctgtgagccc tttcctgcca
1021 aggtgcagct tacgtagttg aggcagggtg agtagctgct tgacacccca gtgagtcagg
1081 ccaaaactga gatgtgttta atgaagattt atggagtaag gacttaaaat catacatctt
1141 ggagaacctt tcttactcat ttcagtccca tctaaaaatg tgtcagctat tctaaatccc
1201 aacttaaatt gttcttacgg tttctagaaa ctttcctttt cagtttccag aaatacaagt
1261 tagataattg gctacttaac tgatgaaaga tgagcccaag tccacctgtc ttcatcctcc
1321 cctgcactcc agactgatct gcctaaagca cgcgagatgc aggcgaaaag cagccacacc
1381 cctctgccac aaatgaccaa cagctggtca ggacgttaca cgcggtgcct tgtaagaggc
1441 aagaaacact tgccgaatct gcatctggct tccagtggta agcacattcc tcagcaggat
1501 caagccaaac agtaaaaact accaagagaa cacgaggaag gcagaaacga tgtttagcaa
1561 cagtattctg catggttcac tgcttaagaa aatgccttct ggaatatttg taaactgaaa
1621 ttctgtatgt gtaagagatg tttaaatatg tttgggtcct aaacagcttt ttaaaattat
1681 acttgggaat aaattcagca tcttttcaaa taaactctat gaaagacaaa aaaaaaaaaa
1741 aaa
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