LOCUS BC101658 2350 bp mRNA linear HUM 06-MAR-2007
DEFINITION Homo sapiens membrane metallo-endopeptidase, mRNA (cDNA clone
MGC:126707 IMAGE:8069164), complete cds.
ACCESSION BC101658
VERSION BC101658.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2350)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2350)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-AUG-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 2 Row: I Column: 2.
FEATURES Location/Qualifiers
source 1..2350
/db_xref="H-InvDB:HIT000337015"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:126707 IMAGE:8069164"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_311"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: GCCAAGGG"
gene 1..2350
/gene="MME"
/gene_synonym="CALLA"
/gene_synonym="CD10"
/gene_synonym="NEP"
/db_xref="GeneID:4311"
/db_xref="HGNC:HGNC:7154"
/db_xref="MIM:120520"
CDS 77..2329
/gene="MME"
/gene_synonym="CALLA"
/gene_synonym="CD10"
/gene_synonym="NEP"
/codon_start=1
/product="membrane metallo-endopeptidase"
/protein_id="AAI01659.1"
/db_xref="GeneID:4311"
/db_xref="HGNC:HGNC:7154"
/db_xref="MIM:120520"
/translation="MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVT
MIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSS
RYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKL
LPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIH
IDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKV
MELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTV
NISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRN
AFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREV
FIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYF
ENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFS
AQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVY
QYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNH
KQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSY
MNPEKKCRVW"
BASE COUNT 766 a 448 c 519 g 617 t
ORIGIN
1 ggggctggga atttgccatt ctgctgtaca gacactgatt tttttttctt ctttttaaaa
61 agcaagattt taggtgatgg gcaagtcaga aagtcagatg gatataactg atatcaacac
121 tccaaagcca aagaagaaac agcgatggac tccactggag atcagcctct cggtccttgt
181 cctgctcctc accatcatag ctgtgacaat gatcgcactc tatgcaacct acgatgatgg
241 tatttgcaag tcatcagact gcataaaatc agctgctcga ctgatccaaa acatggatgc
301 caccactgag ccttgtacag actttttcaa atatgcttgc ggaggctggt tgaaacgtaa
361 tgtcattccc gagaccagct cccgttacgg caactttgac attttaagag atgaactaga
421 agtcgttttg aaagatgtcc ttcaagaacc caaaactgaa gatatagtag cagtgcagaa
481 agcaaaagca ttgtacaggt cttgtataaa tgaatctgct attgatagca gaggtggaga
541 acctctactc aaactgttac cagacatata tgggtggcca gtagcaacag aaaactggga
601 gcaaaaatat ggtgcttctt ggacagctga aaaagctatt gcacaactga attctaaata
661 tgggaaaaaa gtccttatta atttgtttgt tggcactgat gataagaatt ctgtgaatca
721 tgtaattcat attgaccaac ctcgacttgg cctcccttct agagattact atgaatgcac
781 tggaatctat aaagaggctt gtacagcata tgtggatttt atgatttctg tggccagatt
841 gattcgtcag gaagaaagat tgcccatcga tgaaaaccag cttgctttgg aaatgaataa
901 agttatggaa ttggaaaaag aaattgccaa tgctacggct aaacctgaag atcgaaatga
961 tccaatgctt ctgtataaca agatgacatt ggcccagatc caaaataact tttcactaga
1021 gatcaatggg aagccattca gctggttgaa tttcacaaat gaaatcatgt caactgtgaa
1081 tattagtatt acaaatgagg aagatgtggt tgtttatgct ccagaatatt taaccaaact
1141 taagcccatt cttaccaaat attctgccag agatcttcaa aatttaatgt cctggagatt
1201 cataatggat cttgtaagca gcctcagccg aacctacaag gagtccagaa atgctttccg
1261 caaggccctt tatggtacaa cctcagaaac agcaacttgg agacgttgtg caaactatgt
1321 caatgggaat atggaaaatg ctgtggggag gctttatgtg gaagcagcat ttgctggaga
1381 gagtaaacat gtggtcgagg atttgattgc acagatccga gaagttttta ttcagacttt
1441 agatgacctc acttggatgg atgccgagac aaaaaagaga gctgaagaaa aggccttagc
1501 aattaaagaa aggatcggct atcctgatga cattgtttca aatgataaca aactgaataa
1561 tgagtacctc gagttgaact acaaagaaga tgaatacttc gagaacataa ttcaaaattt
1621 gaaattcagc caaagtaaac aactgaagaa gctccgagaa aaggtggaca aagatgagtg
1681 gataagtgga gcagctgtag tcaatgcatt ttactcttca ggaagaaatc agatagtctt
1741 cccagccggc attctgcagc cccccttctt tagtgcccag cagtccaact cattgaacta
1801 tgggggcatc ggcatggtca taggacacga aatcacccat ggcttcgatg acaatggcag
1861 aaactttaac aaagatggag acctcgttga ctggtggact caacagtctg caagtaactt
1921 taaggagcaa tcccagtgca tggtgtatca gtatggaaac ttttcctggg acctggcagg
1981 tggacagcac cttaatggaa ttaatacact gggagaaaac attgctgata atggaggtct
2041 tggtcaagca tacagagcct atcagaatta tattaaaaag aatggcgaag aaaaattact
2101 tcctggactt gacctaaatc acaaacaact atttttcttg aactttgcac aggtgtggtg
2161 tggaacctat aggccagagt atgcggttaa ctccattaaa acagatgtgc acagtccagg
2221 caatttcagg attattggga ctttgcagaa ctctgcagag ttttcagaag cctttcactg
2281 ccgcaagaat tcatacatga atccagaaaa gaagtgccgg gtttggtgat cttcaaaaga
2341 agcattgcag
//