LOCUS BC099715 2664 bp mRNA linear HUM 21-JAN-2006
DEFINITION Homo sapiens Rho guanine nucleotide exchange factor (GEF) 3, mRNA
(cDNA clone MGC:118905 IMAGE:40001659), complete cds.
ACCESSION BC099715
VERSION BC099715.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2664)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2664)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-JUL-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 4 Row: b Column: 18.
FEATURES Location/Qualifiers
source 1..2664
/db_xref="H-InvDB:HIT000336095"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:118905 IMAGE:40001659"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert"
gene 1..2664
/gene="ARHGEF3"
/gene_synonym="DKFZP434F2429"
/gene_synonym="GEF3"
/gene_synonym="STA3"
/gene_synonym="XPLN"
/db_xref="GeneID:50650"
/db_xref="HGNC:HGNC:683"
/db_xref="IMGT/GENE-DB:683"
/db_xref="MIM:683"
CDS 652..1626
/gene="ARHGEF3"
/gene_synonym="DKFZP434F2429"
/gene_synonym="GEF3"
/gene_synonym="STA3"
/gene_synonym="XPLN"
/codon_start=1
/product="ARHGEF3 protein"
/protein_id="AAH99715.1"
/db_xref="GeneID:50650"
/db_xref="HGNC:HGNC:683"
/db_xref="IMGT/GENE-DB:683"
/db_xref="MIM:683"
/translation="MKLPCLSSYDSYCSNQVAAKALLDHKKQDHRVQDFLQRCLESPF
SRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAEINTK
TGESECRYYKERLLYLEEGQKDSLIDSSRVVCCHGELKNNRGVKLHVFLFQEVLVITR
AVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVSFKN
GSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGSRELQ
GETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV"
BASE COUNT 749 a 642 c 648 g 625 t
ORIGIN
1 tgtcggtctc cgtgtcgccg ccgccgcccg gcatcgtgga gctggggccc ccttttgcct
61 gggagttttg tagtcgccta gggtcagcgg tgacatccca aagggcaggc ccggcagccg
121 ccatggtggc caaggattac cccttctacc tcacggtcaa gagagcgaac tgcagcctgg
181 agctacctcc ggccagcggt ccggccaagg acgctgagga gcctagtaat aaacgggtca
241 aacccctttc ccgagtcacg tcgctagcaa acctcatccc gcccgtgaag gccacgccat
301 taaagcgctt cagtcaaacc ctgcagcgct ccattagctt ccgcagtgag agccgccctg
361 acatcctcgc cccccgaccc tggtccagaa atgccgcccc ctcgagcacg aaacggagag
421 atagcaagct gtggagtgag accttcgatg tgtgcgtcaa tcagatgctt acatccaagg
481 aaatcaaacg tcaggaggcg atctttgagc tttcccaagg agaagaagac ttgatagaag
541 acttgaaatt agcaaaaaag gcctatcatg accccatgct gaaactctcc ataatgacag
601 aacaagagtt gaatcaaatt tttggaacac tggactctct aattcctcta catgaagctc
661 ccttgcctca gctcctatga tagctactgc agcaatcaag tagccgccaa agctctgctg
721 gaccacaaaa agcaagatca ccgagtccag gatttcctac agcgatgttt agaatccccc
781 tttagccgca aactagatct ctggaatttc ctcgatattc caagaagccg cctggtaaaa
841 taccctctgc ttctccgaga aatcttgagg cacacaccaa atgataatcc agatcagcag
901 cacttggaag aagctataaa tatcattcag ggaattgtgg cagaaatcaa caccaagact
961 ggtgaatctg aatgccgcta ttataaagag cggcttcttt acttggaaga aggccagaaa
1021 gactccctga tcgacagctc tcgagtcgtg tgttgtcatg gtgaactgaa gaacaatcgg
1081 ggcgtgaaac tgcatgtttt cctgttccaa gaagtgcttg tgatcactcg agccgtcacc
1141 cacaatgagc agctttgcta ccagctgtac cgtcagccaa tccccgtgaa agacctcctg
1201 ctggaagacc tccaggatgg agaagtgagg ctgggtggct ccctgcgagg ggcattcagc
1261 aacaatgaga gaattaaaaa cttcttcaga gtcagtttca aaaatggatc ccaaagtcag
1321 acccactcgc tacaagccaa tgacactttc aacaaacagc agtggcttaa ctgtattcgt
1381 caagccaaag aaacagtttt gtgtgctgcc gggcaagctg gggtgcttga ctccgaggga
1441 tcgttcctaa atcccaccac cgggagcaga gagctacagg gagaaacaaa acttgagcag
1501 atggaccaat cggacagtga gtcagactgt agtatggaca cgagtgaggt cagcctcgac
1561 tgtgagcgca tggaacagac agactcttcc tgtggaaaca gcaggcacgg tgaaagtaac
1621 gtctgacaga agcatgtgca cttcgggaag caggcctgca tcttacctgt acagtatttg
1681 cattccacag atggaacggt ttggagaagc actttttcat acttttgtga aagtatacat
1741 gttggcccag tctctcgtat ctgtaccttt gtccctagta ctgtaactgc caatctgtct
1801 gtgtaagctg gaatctgtgg caactattac cctgtgttgt atttcccaag tgtctggatg
1861 gatggagagg tactcaaaca agttactttc agttgtcctg ctggatttta aaaaaataga
1921 aaaagaatct caaaactact gttttacata gattgtttga agagtccttc ctcttgtgct
1981 tctgtaccac tttcccagct cttagatgtg gtagctaaag gcacggaatt tagacggcct
2041 tgtaaatagg gcatgaggaa ctcatctgtg tattgggatg gtattagaga gagaatcagg
2101 aaagaccaac tcatgaagtg aacttggttt gatcttactc aactagaaag cttgaaaaca
2161 tccctgggga ttctgaaggc ttaattttgc aaaggaggat gcattgtctg aactttgcaa
2221 cttcatccag tgcaagtttg atgcaagaat gtattaggac ataaaataga ggctgacctt
2281 aaaagggcca ggacagaagc ggctgccagc tctgaatctt taactgaaat gcacatggca
2341 ccaggaggtg tctctcatag ttggttgcta gcctaaaaca tcagaataga acccaaaggg
2401 cttaggaagg cctgccagga taacaagaag gccctgtatt cattgtgttt catctgccta
2461 ggcctactca ttattttaga gaatgaatga agcaacaagg aagagagacc atgactctat
2521 cgatgacact gtttatagaa acacaggaga ggaagaattt ggaatgaaaa gcacttcgtc
2581 agaaccttct gtgggagcca ttgagagaaa agcatggtcc agtgccttct gagaaaggcc
2641 agagctttgg gctttcctgc tctg
//