LOCUS BC098394 4184 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase, mRNA (cDNA clone MGC:104648 IMAGE:4374347), complete
cds.
ACCESSION BC098394
VERSION BC098394.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4184)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4184)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUL-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 198 Row: a Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4507612.
FEATURES Location/Qualifiers
source 1..4184
/db_xref="H-InvDB:HIT000335948"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:104648 IMAGE:4374347"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4184
/gene="TNKS"
/gene_synonym="PARP-5a"
/gene_synonym="PARP5A"
/gene_synonym="PARPL"
/gene_synonym="TIN1"
/gene_synonym="TINF1"
/gene_synonym="TNKS1"
/db_xref="GeneID:8658"
/db_xref="HGNC:HGNC:11941"
/db_xref="MIM:603303"
CDS 29..4012
/gene="TNKS"
/gene_synonym="PARP-5a"
/gene_synonym="PARP5A"
/gene_synonym="PARPL"
/gene_synonym="TIN1"
/gene_synonym="TINF1"
/gene_synonym="TNKS1"
/codon_start=1
/product="tankyrase, TRF1-interacting ankyrin-related
ADP-ribose polymerase"
/protein_id="AAH98394.1"
/db_xref="GeneID:8658"
/db_xref="HGNC:HGNC:11941"
/db_xref="MIM:603303"
/translation="MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGTT
PASPTASGLAPFASPRHGLALPEGDGSRDPPDRPRSPDQVDGTSCCSTTSTICTVAAA
PVVPAVSTSSAAGVAPNPAGSGSNNSPSSSSSPTSSSSSSPSSPGSSLAESPEAAGVS
STAPLGPGAAGPGTGVPAVSGALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSS
PLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPN
ARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEY
KKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHG
ADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEV
CSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKT
LALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAA
ERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQG
FTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEG
RHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG
ASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQ
DLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYL
LEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKG
RTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFKPQATVV
SASLISPASTPSCLSAASSIDNLTGPLAGLAVGGASNAGDGAAGTERKEGEVAGLDMN
ISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLIKGVERLLG
GQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYN
VIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYI
GGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQ
FSTIKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTA
TAAEQKT"
BASE COUNT 1140 a 1045 c 1045 g 954 t
ORIGIN
1 gcagtgacag tgctagggga gtccgaagat ggcggcgtcg cgtcgctctc agcatcatca
61 ccaccatcat caacaacagc tccagcccgc cccaggggct tcagcgccgc cgccgccacc
121 tcctccccca ctcagccctg gcctggcccc ggggaccacc ccagcctctc ccacggccag
181 cggcctggcc cccttcgcct ccccgcggca cggcctagcg ctgccggagg gggatggcag
241 tcgggatccg cccgacaggc cccgatcccc ggaccaggtt gacggtacca gctgttgcag
301 taccaccagc acaatctgta ccgtcgccgc cgctcccgtg gtcccagcgg tttctacttc
361 atctgccgct ggggtcgctc ccaacccagc cggcagtggc agtaacaatt caccgtcgtc
421 ctcttcttcc ccgacttctt cctcatcttc ctctccatcc tcccctggat cgagcttggc
481 ggagagcccc gaggcggccg gagttagcag cacagcacca ctggggcctg gggcagcagg
541 acctgggact ggggtcccag cagtgagcgg ggccctacgg gaactgctgg aggcctgtcg
601 caatggggac gtgtcccggg taaagagact ggtggacgcg gcaaacgtaa atgcaaagga
661 catggccggc cggaagtctt ctcccctgca cttcgctgca ggttttggaa ggaaggatgt
721 tgtagaacac ttactacaga tgggtgctaa tgtccacgct cgtgatgatg gaggtctcat
781 cccgcttcat aatgcctgtt cttttggcca tgctgaggtt gtgagtctgt tattgtgcca
841 aggagctgat ccaaatgcca gggataactg gaactataca cctctgcatg aagctgctat
901 taaagggaag atcgatgtgt gcattgtgct gctgcagcac ggagctgacc caaacattcg
961 gaacactgat gggaaatcag ccctggacct ggcagatcct tcagcaaaag ctgtccttac
1021 aggtgaatac aagaaagacg aactcctaga agctgctagg agtggtaatg aagaaaaact
1081 aatggcttta ctgactcctc taaatgtgaa ttgccatgca agtgatgggc gaaagtcgac
1141 tcctttacat ctagcagcgg gctacaacag agttcgaata gttcagcttc ttcttcagca
1201 tggtgctgat gttcatgcaa aagacaaagg tggacttgtg cctcttcata atgcatgttc
1261 atatggacat tatgaagtca cagaactgct actaaagcat ggagcttgtg ttaatgccat
1321 ggatctctgg cagtttactc cactgcacga ggctgcttcc aagaaccgtg tagaagtctg
1381 ctctttgtta cttagccatg gcgctgatcc tacgttagtc aactgccatg gcaaaagtgc
1441 tgtggatatg gctccaactc cggagcttag ggagagattg acttatgaat ttaaaggtca
1501 ttctttacta caagcagcca gagaagcaga cttagctaaa gttaaaaaaa cactcgctct
1561 ggaaatcatt aatttcaaac aaccgcagtc tcatgaaaca gcactgcact gtgctgtggc
1621 ctctctgcat cccaaacgta aacaagtgac agaattgtta cttagaaaag gagcaaatgt
1681 taatgaaaaa aataaagatt tcatgactcc cctacatgtt gcagccgaaa gagcccataa
1741 tgatgtcatg gaagttctgc ataagcatgg cgccaagatg aatgcactgg acacccttgg
1801 tcagactgct ttgcatagag ccgccctagc aggccacctg cagacctgcc gcctcctgct
1861 gagttacggc tctgacccct ccatcatctc cttacaaggc ttcacagcag cacagatggg
1921 caatgaagca gtgcagcaga ttctgagtga gagtacacct atacgtactt ctgatgttga
1981 ttatcgactc ttagaggcat ctaaagctgg agacttggaa actgtgaagc aactttgcag
2041 ctctcaaaat gtgaattgta gagacttaga gggccggcat tccacgccct tacacttcgc
2101 agcaggctac aaccgcgtgt ctgttgtaga gtacctgcta caccacggtg ccgatgtcca
2161 tgccaaagac aagggtggct tggtgcccct tcataatgcc tgttcatatg gacactatga
2221 ggtggctgag cttttagtaa ggcatggggc ttctgtcaat gtggcggact tatggaaatt
2281 tacccctctc catgaagcag cagctaaagg gaagtatgaa atctgcaagc tccttttaaa
2341 acatggagca gatccaacta aaaagaacag agatggaaat acacctttgg atttggtaaa
2401 ggaaggagac acagatattc aggacttact gagaggggat gctgctttgt tggatgctgc
2461 caagaagggc tgcctggcaa gagtgcagaa gctctgtacc ccagagaata tcaactgcag
2521 agacacccag ggcagaaatt caacccctct gcacctggca gcaggctata ataacctgga
2581 agtagctgaa tatcttctag agcatggagc tgatgttaat gcccaggaca agggtggttt
2641 aattcctctt cataatgcgg catcttatgg gcatgttgac atagcggctt tattgataaa
2701 atacaacacg tgtgtaaatg caacagataa gtgggcgttt actcccctcc atgaagcagc
2761 ccagaaagga aggacgcagc tgtgcgccct cctcctagcg catggtgcag accccaccat
2821 gaagaaccag gaaggccaga cgcctctgga tctggcaaca gctgacgata tcagagcttt
2881 gctgatagat gccatgcccc cagaggcctt acctacctgt tttaaacctc aggctactgt
2941 agtgagtgcc tctctgatct caccagcatc caccccctcc tgcctctcgg ctgccagcag
3001 catagacaac ctcactggcc ctttagcagg gttggccgta ggaggagcct ccaatgcagg
3061 ggatggcgcc gcgggaacag aaaggaagga aggagaagtt gctggtcttg acatgaatat
3121 cagccaattt ctaaaaagcc ttggccttga acaccttcgg gatatctttg aaacagaaca
3181 gattacacta gatgtgttgg ctgatatggg tcatgaagag ttgaaagaaa taggcatcaa
3241 tgcatatggg caccgccaca aattaatcaa aggagtagaa agactcttag gtggacaaca
3301 aggcaccaat ccttatttga cttttcactg tgttaatcag ggaacgattt tgctggatct
3361 tgctccagaa gataaagaat atcagtcagt ggaagaagag atgcaaagta ctattcgaga
3421 acacagagat ggtggtaatg ctggcggcat cttcaacaga tacaatgtca ttcgaattca
3481 aaaagttgtc aacaagaagt tgagggagcg gttctgccac cgacagaagg aagtgtctga
3541 ggagaatcac aaccatcaca atgagcgcat gttgtttcat ggttctcctt tcattaatgc
3601 cattattcat aaagggtttg atgagcgaca tgcatacata ggaggaatgt ttggggccgg
3661 gatttatttt gctgaaaact cctcaaaaag caaccaatat gtttatggaa ttggaggagg
3721 aacaggctgc cctacacaca aggacaggtc atgctatata tgtcacagac aaatgctctt
3781 ctgtagagtg acccttggga aatcctttct gcagtttagc accataaaaa tggcccacgc
3841 gcctccaggg caccactcag tcattggtag accgagcgtc aatgggctgg catatgctga
3901 atatgtcatc tacagaggag aacaggcata cccagagtat cttatcactt accagatcat
3961 gaagccagaa gccccttccc agaccgcaac agccgcagag cagaagacct agtgaatgcc
4021 tgctggtgaa ggccagatca gatttcaacc tgggactgga ttacagagga ttgtttctaa
4081 taacaacatc aatattctag aagtccctga cagcctagaa ataagctgtt tgtcttctat
4141 aaagcattgc tatagtgatg aataaaacaa aaaaaaaaaa aaaa
//