LOCUS BC098343 1812 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens protein phosphatase 2C, magnesium-dependent, catalytic
subunit, mRNA (cDNA clone MGC:119646 IMAGE:40010016), complete cds.
ACCESSION BC098343
VERSION BC098343.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1812)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1812)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-JUN-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 4 Row: g Column: 5.
FEATURES Location/Qualifiers
source 1..1812
/db_xref="H-InvDB:HIT000335905"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:119646 IMAGE:40010016"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: TGAAGTAC"
gene 1..1812
/gene="PPM2C"
/gene_synonym="PDH"
/gene_synonym="PDP"
/gene_synonym="PDP1"
/db_xref="GeneID:54704"
/db_xref="HGNC:HGNC:9279"
/db_xref="MIM:605993"
CDS 24..1637
/gene="PPM2C"
/gene_synonym="PDH"
/gene_synonym="PDP"
/gene_synonym="PDP1"
/codon_start=1
/product="protein phosphatase 2C, magnesium-dependent,
catalytic subunit"
/protein_id="AAH98343.1"
/db_xref="GeneID:54704"
/db_xref="HGNC:HGNC:9279"
/db_xref="MIM:605993"
/translation="MPAPTQLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRL
RYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFD
GKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLF
YYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQE
LIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGATACV
AHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEA
KSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTP
PYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGG
YKVTLGQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPE
ELARMYRDDITIIVVQFNSHVVGAYQNQE"
BASE COUNT 496 a 402 c 428 g 486 t
ORIGIN
1 gcctgccact gttctctgat gccatgccag caccaactca actgtttttt cctctcatcc
61 gtaactgtga actgagcagg atctatggca ctgcatgtta ctgccaccac aaacatctct
121 gttgttcctc atcgtacatt cctcagagtc gactgagata cacacctcat ccagcatatg
181 ctaccttttg caggccaaag gagaactggt ggcagtacac ccaaggaagg agatatgctt
241 ccacaccaca gaaattttac ctcacacctc cacaagtcaa tagcatcctt aaagctaatg
301 aatacagttt caaagtgcca gaatttgacg gcaaaaatgt cagttctatc cttggatttg
361 acagcaatca gctgcctgca aatgcaccca ttgaggaccg gagaagtgca gcaacctgct
421 tgcagaccag agggatgctt ttgggggttt ttgatggcca tgcaggttgt gcttgttccc
481 aggcagtcag tgaaagactc ttttattata ttgctgtctc tttgttaccc catgagactt
541 tgctagagat tgaaaatgca gtggagagcg gccgggcact gctacccatt ctccagtggc
601 acaagcaccc caatgattac tttagtaagg aggcatccaa attgtacttt aacagcttga
661 ggacttactg gcaagagctt atagacctca acactggtga gtcgactgat attgatgtta
721 aggaggctct aattaatgcc ttcaagaggc ttgataatga catctccttg gaggcgcaag
781 ttggtgatcc taattctttt ctcaactacc tggtgcttcg agtggcattt tctggagcca
841 ctgcttgtgt ggcccatgtg gatggtgttg accttcatgt ggccaatact ggcgatagca
901 gagccatgct gggtgtgcag gaagaggacg gctcatggtc agcagtcacg ctgtctaatg
961 accacaatgc tcaaaatgaa agagaactag aacggctgaa attggaacat ccaaagagtg
1021 aggccaagag tgtcgtgaaa caggatcggc tgcttggctt gctgatgcca tttagggcat
1081 ttggagatgt aaagttcaaa tggagcattg accttcaaaa gagagtgata gaatctggcc
1141 cagaccagtt gaatgacaat gaatatacca agtttattcc tcctaattat cacacacctc
1201 cttatctcac tgctgagcca gaggtaactt accaccgatt aaggccacag gataagtttc
1261 tggtgttggc tactgatggg ttgtgggaga ctatgcatag gcaggatgtg gttaggattg
1321 tgggtgagta cctaactggc atgcatcacc aacagccaat agctgttggt ggctacaagg
1381 tgactctggg acagatgcat ggccttttaa cagaaaggag aaccaaaatg tcctcggtat
1441 ttgaggatca gaacgcagca acccatctca ttcgccacgc tgtgggcaac aacgagtttg
1501 ggactgttga tcatgagcgc ctctctaaaa tgcttagtct tcctgaagag cttgctcgaa
1561 tgtacagaga tgacattaca atcattgtag ttcagttcaa ttctcatgtt gtaggggcgt
1621 atcaaaacca agaatagtga gtggctcttt cactggcaat tctcaaatga tacacattta
1681 aagggcagat tttttaaaaa gatactacta taataaacat ttccagttgg tcattctaag
1741 catttaccct tttgatactc tagctagtca ggtactccaa attgactttg cagcagggtg
1801 gcagggtcag ga
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