LOCUS BC098122 2742 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens Rho guanine nucleotide exchange factor (GEF) 3, mRNA
(cDNA clone MGC:118903 IMAGE:40001657), complete cds.
ACCESSION BC098122
VERSION BC098122.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2742)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2742)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-JUN-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 4 Row: a Column: 18.
FEATURES Location/Qualifiers
source 1..2742
/db_xref="H-InvDB:HIT000335767"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:118903 IMAGE:40001657"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: GTGTTTCC"
gene 1..2742
/gene="ARHGEF3"
/gene_synonym="DKFZP434F2429"
/gene_synonym="GEF3"
/gene_synonym="STA3"
/gene_synonym="XPLN"
/db_xref="GeneID:50650"
/db_xref="HGNC:HGNC:683"
CDS 123..1703
/gene="ARHGEF3"
/gene_synonym="DKFZP434F2429"
/gene_synonym="GEF3"
/gene_synonym="STA3"
/gene_synonym="XPLN"
/codon_start=1
/product="Rho guanine nucleotide exchange factor (GEF) 3"
/protein_id="AAH98122.2"
/db_xref="GeneID:50650"
/db_xref="HGNC:HGNC:683"
/translation="MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSR
VTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSK
LWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTE
QELNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQ
VAAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRH
TPNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRV
VCCHGELKNNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDG
EVRLGGSLRGAFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKET
VLCAAGQAGVLDSEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCER
MEQTDSSCGNSRHGESNV"
BASE COUNT 763 a 663 c 671 g 645 t
ORIGIN
1 tgtcggtctc cgtgtcgccg ccgccgcccg gcatcgtgga gctggggccc ccttttgcct
61 gggagttttg tagtcgccta gggtcagcgg tgacatccca aagggcaggc ccggcagccg
121 ccatggtggc caaggattac cccttctacc tcacggtcaa gagagcgaac tgcagcctgg
181 agctaccccc ggccagcggt ccggccaagg acgctgagga gcctagtaat aaacgggtca
241 aacccctttc ccgagtcacg tcgctagcaa acctcatccc gcccgtgaag gccacgccat
301 taaagcgctt cagtcaaacc ctgcagcgct ccattagctt ccgcagtgag agccgccctg
361 acatcctcgc cccccgaccc tggtccagaa atgccgcccc ctcgagcacg aaacggagag
421 atagcaagct gtggagtgag accttcgatg tgtgcgtcaa tcagatgctt acatccaagg
481 aaatcaaacg tcaggaggcg atctttgagc tttcccaagg agaagaagac ttgatagaag
541 acttgaaatt agcaaaaaag gcctatcatg accccatgct gaaactctcc ataatgacag
601 aacaagagtt gaatcaaatt tttggaacac tggactctct aattcctcta catgaagagc
661 tccttagtca gcttcgagat gttaggaagc ctgatggctc gactgaacat gttggtccca
721 tcctcgtggg ctggctccct tgcctcagct cctatgatag ctactgcagc aatcaagtag
781 ccgccaaagc tctgctggac cacaaaaagc aagatcaccg agtccaggat ttcctacagc
841 gatgtttaga atcccccttt agccgcaaac tagatctctg gaatttcctc gatattccaa
901 gaagccgcct ggtaaaatac cctctgcttc tccgagaaat cttgaggcac acaccaaatg
961 ataatccaga tcagcagcac ttggaagaag ctataaatat cattcaggga attgtggcag
1021 aaatcaacac caagactggt gaatctgaat gccgctatta taaagagcgg cttctttact
1081 tggaagaagg ccagaaagac tccctgatcg acagctctcg agtcgtgtgt tgtcatggtg
1141 aactgaagaa caatcggggc gtgaaactgc atgttttcct gttccaagaa gtgcttgtga
1201 tcactcgagc cgtcacccac aatgagcagc tttgctacca gctgtaccgt cagccaatcc
1261 ccgtgaaaga cctcctgctg gaagacctcc aggatggaga agtgaggctg ggtggctccc
1321 tgcgaggggc attcagcaac aatgagagaa ttaaaaactt cttcagagtc agtttcaaaa
1381 atggatccca aagtcagacc cactcgctac aagccaatga cactttcaac aaacagcagt
1441 ggcttaactg tattcgtcaa gccaaagaaa cagttttgtg tgctgccggg caagctgggg
1501 tgcttgactc cgagggatcg ttcctaaatc ccaccaccgg gagcagagag ctacagggag
1561 aaacaaaact tgagcagatg gaccaatcgg acagtgagtc agactgtagt atggacacga
1621 gtgaggtcag cctcgactgt gagcgcatgg aacagacaga ctcttcctgt ggaaacagca
1681 ggcacggtga aagtaacgtc tgacagaagc atgtgcactt cgggaagcag gcctgcatct
1741 tacctgtaca gtatttgcat tccacagatg gaacggtttg gagaagcact ttttcatact
1801 tttgtgaaag tatacatgtt ggcccagtct ctcgtatctg tacctttgtc cctagtactg
1861 taactgccaa tctgtctgtg taagctggaa tctgtggcaa ctattaccct gtgttgtatt
1921 tcccaagtgt ctggatggat ggagaggtac tcaaacaagt tactttcagt tgtcctgctg
1981 gattttaaaa aaatagaaaa agaatctcaa aactactgtt ttacatagat tgtttgaaga
2041 gtccttcctc ttgtgcttct gtaccacttt cccagctctt agatgtggta gctaaaggca
2101 cggaatttag acggccttgt aaatagggca tgaggaactc atctgtgtat tgggatggta
2161 ttagagagag aatcaggaaa gaccaactca tgaagtgaac ttggtttgat cttactcaac
2221 tagaaagctt gaaaacatcc ctggggattc tgaaggctta attttgcaaa ggaggatgca
2281 ttgtctgaac tttgcaactt catccagtgc aagtttgatg caagaatgta ttaggacata
2341 aaatagaggc tgaccttaaa agggccagga cagaagcggc tgccagctct gaatctttaa
2401 ctgaaatgca catggcacca ggaggtgtct ctcatagttg gttgctagcc taaaacatca
2461 gaatagaacc caaagggctt aggaaggcct gccaggataa caagaaggcc ctgtattcat
2521 tgtgtttcat ctgcctaggc ctactcatta ttttagagaa tgaatgaagc aacaaggaag
2581 agagaccatg actctatcga tgacactgtt tatagaaaca caggagagga agaatttgga
2641 atgaaaagca cttcgtcaga accttctgtg ggagccattg agagaaaagc atggtccagt
2701 gccttctgag aaaggccaga gctttgggct ttcctgctct gc
//