LOCUS BC094726 5149 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens oculocerebrorenal syndrome of Lowe, mRNA (cDNA clone
MGC:104549 IMAGE:30528571), complete cds.
ACCESSION BC094726
VERSION BC094726.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5149)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5149)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-MAY-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 198 Row: n Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21396493.
FEATURES Location/Qualifiers
source 1..5149
/db_xref="H-InvDB:HIT000335027"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:104549 IMAGE:30528571"
/tissue_type="Placenta, normal"
/clone_lib="NIH_MGC_147"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..5149
/gene="OCRL"
/gene_synonym="INPP5F"
/gene_synonym="LOCR"
/gene_synonym="NPHL2"
/gene_synonym="OCRL1"
/db_xref="GeneID:4952"
/db_xref="HGNC:HGNC:8108"
/db_xref="MIM:300535"
CDS 170..2851
/gene="OCRL"
/gene_synonym="INPP5F"
/gene_synonym="LOCR"
/gene_synonym="NPHL2"
/gene_synonym="OCRL1"
/codon_start=1
/product="oculocerebrorenal syndrome of Lowe"
/protein_id="AAH94726.1"
/db_xref="GeneID:4952"
/db_xref="HGNC:HGNC:8108"
/db_xref="MIM:300535"
/translation="MEPPLPVGAQPLATVEGMEMKGPLREPCALTLAQRNGQYELIIQ
LHEKEQHVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEE
HCLKFLSAVLAAQKAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNL
DKKINSQNQPTGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQ
REGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGF
QELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCR
YIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKD
ICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLGMPDANEVKSLINKKDLQRLLKF
DQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNV
NQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDSVRIMDRMENDFLPSLE
LSRREFVFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYL
EPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGT
SLEALCRMKRPIREVPVTKLIDLEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKY
ACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYE
LYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMIATLF
TSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED"
BASE COUNT 1377 a 1186 c 1156 g 1430 t
ORIGIN
1 agattctcag ctcccagctc cccgctcccg gctcccggcg cccggcgccc ggcgcggagc
61 tgttcctcaa acgacacgca gccgaggtgg gtgggtgtgg ggacgcggga gccagtgtcg
121 tcggatcggc ccgcagtccg ctgtcctgct gagcccggag gccgcctgga tggagccgcc
181 gctcccggtc ggagcccagc cgcttgccac tgtcgagggt atggagatga agggtcctct
241 ccgggagccc tgcgccctga ccctagccca gaggaacggg caatatgagt taataatcca
301 gttgcatgag aaggaacagc atgttcaaga tatcattcct ataaatagcc acttcagatg
361 tgttcaagaa gcagaagaaa ctcttttgat tgacatagct tctaacagtg gctgcaaaat
421 tcgggttcag ggggactgga tcagagagcg ccgctttgaa atccctgatg aggaacactg
481 tttgaagttc ctctcagctg tccttgctgc tcagaaagct cagtcacagc ttcttgttcc
541 agagcaaaag gactcatcta gctggtacca gaaattagac actaaggaca aaccttctgt
601 tttttcaggg cttcttggat ttgaagacaa tttttcttct atgaatttgg acaagaaaat
661 aaattcacaa aatcagccta ctgggattca tcgggaaccc ccacctccac ccttttcagt
721 gaataaaatg cttccacgtg aaaaagaagc ttctaacaag gagcagccca aagtgaccaa
781 caccatgcgg aagctctttg taccaaatac ccaatctggg cagcgggagg gtctcatcaa
841 acatatcctg gcaaagcgag agaaagaata tgtcaacatt cagactttca gattttttgt
901 tggaacttgg aatgtgaatg gccagtctcc agatagcggg ttagaacctt ggctgaactg
961 tgatcccaat cctcctgata tctactgcat tggattccaa gaactggact tgagcacaga
1021 agccttcttc tactttgaat ctgtgaagga acaagaatgg tccatggctg tagagagagg
1081 tttgcattcc aaagccaagt ataagaaagt tcaactggtg cgccttgttg ggatgatgct
1141 tcttatattt gccagaaagg atcagtgtcg atacattcgt gatattgcta cagaaacagt
1201 tggaactgga atcatgggga aaatgggaaa caaaggtggg gtagctgtga gatttgtatt
1261 tcacaacacc accttttgca ttgtcaattc ccatctggct gcacacgtgg aggactttga
1321 gagaaggaat caagattata aggacatttg tgcgagaatg agttttgtgg tcccaaatca
1381 gaccctcccg cagttgaaca tcatgaaaca tgaggttgtc atttggttgg gagatttgaa
1441 ttatagactt ggcatgcctg atgccaatga ggtgaaaagt cttattaata agaaagacct
1501 tcagagactc ttgaaattcg accagctaaa tattcagcgc acacagaaaa aagcttttgt
1561 tgacttcaat gaaggggaaa tcaagttcat ccccacttat aagtatgact ctaaaacaga
1621 ccggtgggat tccagtggga aatgccgggt tccagcctgg tgtgaccgaa ttctttggag
1681 aggaacaaat gttaatcagc ttaattatcg gagtcacatg gaactgaaaa ccagcgacca
1741 caagcctgtt agcgccctct tccatattgg ggtgaaggtt gtggatgaac gaaggtaccg
1801 gaaagtcttt gaagatagtg tacgcatcat ggacagaatg gaaaatgact tccttccttc
1861 cttagaactc agcaggaggg agtttgtgtt tgaaaatgtg aagtttcggc aactacaaaa
1921 ggagaagttc cagatcagca acaatggaca ggttccctgc catttttctt tcatccctaa
1981 acttaatgac agccagtact gcaagccatg gcttcgggct gaaccttttg agggctactt
2041 ggagccaaat gagacagtgg acatttctct tgatgtgtat gtcagcaaag actctgtaac
2101 catcctgaac tcgggagaag ataagattga agatattctc gtccttcacc tggatcgagg
2161 caaagattac ttcttgacta tcagtggaaa ttacctccca agttgttttg gcacatcctt
2221 agaggctctg tgccgtatga aaagaccaat ccgagaagtt cctgttacca aactcataga
2281 cttggagaaa tcccttctgc aaatggttcc tttggatgaa ggtgccagtg agaggcccct
2341 tcaggttccc aaggagatct ggcttctagt agatcaccta ttcaaatacg cctgtcacca
2401 ggaggacctg ttccagaccc ctggaatgca ggaagagctc cagcagatca ttgattgtct
2461 ggataccagc attcctgaga caatccctgg cagcaaccac tctgtggctg aagcactgct
2521 cattttcttg gaagccctgc cagagccagt catctgttac gagctgtatc agcgatgtct
2581 tgactctgct tatgatcccc ggatctgccg acaggtgatc tcccagcttc cgagatgcca
2641 tagaaatgtt ttccgttact tgatggcatt ccttcgagaa ctcttaaaat tctctgaata
2701 caatagcgtc aatgccaaca tgatcgctac tctcttcact agtcttctcc tgaggcctcc
2761 acccaacctt atggcaagac agactccaag tgaccgccag cgtgctattc agttccttct
2821 gggctttctg cttgggagcg aagaagacta aggcttttac tgttctctga tattctagaa
2881 gcagacgatc tcgggctcca agtatttcag aatgatttaa aaagtcatgc cacaggaagg
2941 gtctattgca gaatttcaag ttctgtttat agtaaaaagg aagagcgttt cctaatccct
3001 cctttaccat atcctacaca gaaaaatact tttagactta tattgccaag ccaaagttac
3061 catattttgg tgtttttgtg ttttctcttt ataaggcaaa aagatctgta tttacactcc
3121 ttcacctagg gatgtgtttg ttgccctcct acccaattgt catgattgtc cttagtaccc
3181 taggcctaga ttctgagatc ttcccattct aggcctacaa gcactacttg ctgtagctga
3241 gacttgtcta gagtcctttg ttttgcactt ttgacccacc ccttcctgga tcactccttt
3301 gcactccact cccctcgttc tgtcactttg aacgaagtct gagtgaggct agtgactcct
3361 tgggtgtcct caacagtgaa ttcactgtct gcgtgcagtt attacatgca tttgtgcatt
3421 tctactacaa tggcatcttt atgtctctgt aacattggcc ttttcatggc tccacactgg
3481 gtggaaccat attctcttag atcacattta gtagcataac tgtagggact attagagatg
3541 gcatctcatc gatgagagag aatcacaatc agaatggaag cactttgagt atctgaagag
3601 tgagagcatt catgtttgac aggtcctgct tcccactatc cttttcctgt tattattcaa
3661 attttacaca aggactaatc ctgggtgtct ctgagaccca tctcctgcct agacatccac
3721 ctccagagca acactggccc cacagtaaaa gaggaagtct tgtacctcag gcaggcccat
3781 ctagagctat tgctccttcc cacagcaaag gtattgtgga tgacccttag aatccattct
3841 ctggtcttct gaaataccaa gggcagatgt cacctccttc ctcagcagga ctgactctgg
3901 gctctacaac cagctccttc acataaaggg tttagagact ccccttggct cccagtcacc
3961 atatccagtg ttgtgtaaag agactggcca acaggaccaa ccaagcacct tacctctccc
4021 atacaagatg accctctgag cttttcattt attcaagctc tgtggtacag ccttttttta
4081 aaataaatta atctatattg gttgacaaac aagccaccaa ccactgactg caaaactgcc
4141 tgatgcagtt gggttcctcc tggttttctt ttgttacaac cacccttgcc tgtttacatt
4201 aattgcaagg agcataacgt acaggctgta tgtacaatcc tgggcattga ctctgtgaca
4261 tttctagcat atccaaggca ccaccagtga tttctcctgt ttcttggtgg gggtgggggg
4321 gaaggtacgt attctgcaat atggctaaac cctttcctga ttgagagtta aagcaatagg
4381 agtcaagtta ctggtgccac agatctggag gtatgatagg tcaggggcta ggtgttgaac
4441 ttagttaatg gaagactgag agcagaacag gtttgtcatc tccgcaaggc cagaaagtga
4501 tcacaaaaag aggcagatga tagacactgg ggtagggtca taccacaggg aaataccttt
4561 cctgggcttg ttttctagca tatcactgac ctgggatctt tgggtgatca agggtgtggt
4621 tagtggaggc tctgtgctgc acgtatgcag tatcctatct ctttctacat cagatcaaaa
4681 cactaagttg gtgtactgcc tcgacctttt tttcagctca tcctggaaca tatacagagt
4741 tgagagtttt agacaatctc taggtagagg agacaagatg tagacccaga cagaagaaat
4801 ctgcttccct accatggcta ttccagcacc ccaacctgta attgccaagt cctctaaggt
4861 actaatttgt agctgctctg aagtaaggat ttcggattca gctggtaggg aaagactctg
4921 cacctgctgt cttagggaag aaatggttca aatccatgtg gtgacattgc attagtctcc
4981 ctttcactgt tttcttattc tgtaattgtt tgttatattt cccaaaaacg tcttgatcac
5041 taagcaaagc tgctagtggg attctatatt tcgtgtcatc ttttttatta taatttattg
5101 caaatttttt tctgaataaa tatatgttgt gcgaaaaaaa aaaaaaaaa
//