LOCUS BC092408 4290 bp mRNA linear HUM 19-APR-2005
DEFINITION Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 2,
mRNA (cDNA clone MGC:102821 IMAGE:6181905), complete cds.
ACCESSION BC092408
VERSION BC092408.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4290)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4290)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-APR-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. James R. Lupski
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 196 Row: b Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4757849.
FEATURES Location/Qualifiers
source 1..4290
/db_xref="H-InvDB:HIT000334386"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:102821 IMAGE:6181905"
/tissue_type="Peripheral Nervous System, dorsal root
ganglion"
/clone_lib="Lupski_dorsal_root_ganglion"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4290
/gene="ABCG2"
/gene_synonym="ABC15"
/gene_synonym="ABCP"
/gene_synonym="BCRP"
/gene_synonym="BCRP1"
/gene_synonym="BMDP"
/gene_synonym="EST157481"
/gene_synonym="MRX"
/gene_synonym="MXR"
/gene_synonym="MXR1"
/db_xref="GeneID:9429"
/db_xref="MIM:603756"
CDS 349..2184
/gene="ABCG2"
/gene_synonym="ABC15"
/gene_synonym="ABCP"
/gene_synonym="BCRP"
/gene_synonym="BCRP1"
/gene_synonym="BMDP"
/gene_synonym="EST157481"
/gene_synonym="MRX"
/gene_synonym="MXR"
/gene_synonym="MXR1"
/codon_start=1
/product="ABCG2 protein"
/protein_id="AAH92408.1"
/db_xref="GeneID:9429"
/db_xref="MIM:603756"
/translation="MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICY
RVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGL
SGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLKFSAALRLATTMTNHEKNER
INRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDS
STANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGY
FESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSKQDKPLIEKLAE
IYVNSSFYKETKAELHQLSGGEKKKKITVFKEISYTTSFCHQLRWVSKRSFKNLLVNP
QASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVV
EKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFV
MMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMVCWSISQPLHLGCHGFS
TSAFHDMDLRLCSIMNFWDKTSAQDSMQQETILVTMQHVLAKNIW"
BASE COUNT 1264 a 845 c 827 g 1354 t
ORIGIN
1 gaaaaaagga acccaaggag ataggagagc tgttaatttc actcgggaca tttcctcgag
61 gctagtttac tcggaaagcc tcaatgttcc ctggtagctg caggatctac tttgggggct
121 gccaagtttc ctctctcatt ctttctcctg ccccaagagc aggcaggaag gaaagttcct
181 ggactgatac tcgtctgttt agtaggcgtg ggtcctggtt gaagtctgtc taggaaaact
241 cctaagtgta gaaatcttct tcgtattacc actgtctctg cactgagatt tgggctgctt
301 tgcttccagc gtcacacatc ataactgaga aagataaaaa ctctccagat gtcttccagt
361 aatgtcgaag tttttatccc agtgtcacaa ggaaacacca atggcttccc cgcgacagct
421 tccaatgacc tgaaggcatt tactgaagga gctgtgttaa gttttcataa catctgctat
481 cgagtaaaac tgaagagtgg ctttctacct tgtcgaaaac cagttgagaa agaaatatta
541 tcgaatatca atgggatcat gaaacctggt ctcaacgcca tcctgggacc cacaggtgga
601 ggcaaatctt cgttattaga tgtcttagct gcaaggaaag atccaagtgg attatctgga
661 gatgttctga taaatggagc accgcgacct gccaatttca aatgtaattc aggttacgtg
721 gtacaagatg atgttgtgat gggcactctg acggtgagag aaaacttaaa gttctcagca
781 gctcttcggc ttgcaacaac tatgacgaat catgaaaaaa acgaacggat taacagggtc
841 attcaagagt taggtctgga taaagtggca gactccaagg ttggaactca gtttatccgt
901 ggtgtgtctg gaggagaaag aaaaaggact agtataggaa tggagcttat cactgatcct
961 tccatcttgt tcttggatga gcctacaact ggcttagact caagcacagc aaatgctgtc
1021 cttttgctcc tgaaaaggat gtctaagcag ggacgaacaa tcatcttctc cattcatcag
1081 cctcgatatt ccatcttcaa gttgtttgat agcctcacct tattggcctc aggaagactt
1141 atgttccacg ggcctgctca ggaggccttg ggatactttg aatcagctgg ttatcactgt
1201 gaggcctata ataaccctgc agacttcttc ttggacatca ttaatggaga ttccactgct
1261 gtggcattaa acagagaaga agactttaaa gccacagaga tcatagagcc ttccaagcag
1321 gataagccac tcatagaaaa attagcggag atttatgtca actcctcctt ctacaaagag
1381 acaaaagctg aattacatca actttccggg ggtgagaaga agaagaagat cacagtcttc
1441 aaggagatca gctacaccac ctccttctgt catcaactca gatgggtttc caagcgttca
1501 ttcaaaaact tgctggttaa tccccaggcc tctatagctc agatcattgt cacagtcgta
1561 ctgggactgg ttataggtgc catttacttt gggctaaaaa atgattctac tggaatccag
1621 aacagagctg gggttctctt cttcctgacg accaaccagt gtttcagcag tgtttcagcc
1681 gtggaactct ttgtggtaga gaagaagctc ttcatacatg aatacatcag cggatactac
1741 agagtgtcat cttatttcct tggaaaactg ttatctgatt tattacccat gaggatgtta
1801 ccaagtatta tatttacctg tatagtgtac ttcatgttag gattgaagcc aaaggcagat
1861 gccttcttcg ttatgatgtt tacccttatg atggtggctt attcagccag ttccatggca
1921 ctggccatag cagcaggtca gagtgtggtt tctgtagcaa cacttctcat gaccatctgt
1981 tttgtgttta tgatggtctg ttggtcaatc tcacaaccat tgcatcttgg ctgtcatggc
2041 ttcagtactt cagcattcca cgatatggat ttacggcttt gcagcataat gaatttttgg
2101 gacaaaactt ctgcccagga ctcaatgcaa caggaaacaa tccttgtaac tatgcaacat
2161 gtactggcga agaatatttg gtaaagcagg gcatcgatct ctcaccctgg ggcttgtgga
2221 agaatcacgt ggccttggct tgtatgattg ttattttcct cacaattgcc tacctgaaat
2281 tgttatttct taaaaaatat tcttaaattt ccccttaatt cagtatgatt tatcctcaca
2341 taaaaaagaa gcactttgat tgaagtattc aatcaagttt ttttgttgtt ttctgttccc
2401 ttgccatcac actgttgcac agcagcaatt gttttaaaga gatacatttt tagaaatcac
2461 aacaaactga attaaacatg aaagaaccca agacatcatg tatcgcatat tagttaatct
2521 cctcagacag taaccatggg gaagaaatct ggtctaattt attaatctaa aaaaggagaa
2581 ttgaattctg gaaactcctg acaagttatt actgtctctg gcatttgttt cctcatcttt
2641 aaaatgaata ggtaggttag tagcccttca gtcttaatac tttatgatgc tatggtttgc
2701 cattatttaa taaatgacaa atgtattaat gctatactgg aaatgtaaaa ttgaaaatat
2761 gttggaaaaa agattctgtc ttatagggta aaaaaagcca ccgtgataga aaaaaaatct
2821 ttttgataag cacattaaag ttaatagaac ttactgatat tcctgtctag tggtataata
2881 tctcaggaat cttggctgag ggtttggaac tgtgggtaga gtagagggcc aggagtccag
2941 taatagaatt cttgcaccat ttctggaaca ttctagctct gggaggtcac gtaaccttct
3001 tggggtagtt cagtggttta gtggtttata atccaggtgt gcgtcagaat catctgagga
3061 actttgctaa aatacaaaaa tctggcctaa gtagctccag atctaccttc ataaaggaat
3121 ctgaccactc ctggatttgg taatttccaa gttctgaaaa ttttacttag gatttaataa
3181 ctattaacat ctgtccctac ataggttttc tttcctactt atatacctta tgttctcttc
3241 attctaacct tcatcagtaa tagggaaatg ttttaatttt atttttttag ttgaagggta
3301 atgtaccaaa aaatatagtt cagtgaatta aaatgaacac acatgtgcaa ccatcaattc
3361 aggtcaagaa atagaagatt gtagcacaca aaagcctact cagccattct cccagtcact
3421 acttccttcc ttacccctgg gttatttttg aaatgacact tgatgtattt ccctctgttg
3481 ctgttatgag aacattgcta cagccaagtg ttgtgtttct gtgtgcatag gttgatactt
3541 aattatctcc ccacttttta ataaactttt aatttggaaa taattttaga ttgacagaaa
3601 agttgcaaag atagtgagga aagttcctgt ctactctttg ctcagcttcc cttaatgtta
3661 acattttata tagcaagatg catttgtcaa agctaacaag ttaacattgg tacaatcact
3721 gttaattaaa ctgcacacaa tattcagatt tcaccacttt tccactaata ttctttcatt
3781 gttctaggat tcaattcagg agaccacatt tcatctagcc ctctttttta aaagtaaata
3841 cttttcagca cttacaggag ttaactgagc tggggcatca tggtgtatag acgccctgac
3901 actggtcatc ttggaattca tttagtttgt cagtgggtgc cctgacattc tgtcacaaca
3961 tcaatttggg aacatggcat tatattttta tctttgaact tttttctttt tggatgacat
4021 ttgattaatg cgtcatcttg gaacacatta tcttttttct tggttatgtg atcaggaaga
4081 ttaatcagtt tttcctgttc ttggtataat tcctgctttt cacatacctg tcccttacag
4141 ttctctatat atacccttcc cttattacac agagagaaat atctatctat actttttaca
4201 caaaatatac ttcaaaagaa acaaaacagc cacaattatt aactttttaa ataaatgaga
4261 atttaattat atcctaaaaa aaaaaaaaaa
//