LOCUS BC091499 1797 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens peripheral myelin protein 22, mRNA (cDNA clone
MGC:111095 IMAGE:30395315), complete cds.
ACCESSION BC091499
VERSION BC091499.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1797)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1797)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Michael Brownstein
cDNA Library Preparation: Invitrogen Corp
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 196 Row: j Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24430164.
FEATURES Location/Qualifiers
source 1..1797
/db_xref="H-InvDB:HIT000334349"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:111095 IMAGE:30395315"
/tissue_type="White Matter pool- 5 brain tissues- femoral
artery, olfactory tract, optic tract, cerebellar white
matter, cerebral white matter."
/clone_lib="NIH_MGC_181"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene 1..1797
/gene="PMP22"
/gene_synonym="CMT1A"
/gene_synonym="CMT1E"
/gene_synonym="DSS"
/gene_synonym="GAS-3"
/gene_synonym="HMSNIA"
/gene_synonym="HNPP"
/gene_synonym="MGC20769"
/gene_synonym="Sp110"
/db_xref="GeneID:5376"
/db_xref="HGNC:HGNC:9118"
/db_xref="MIM:601097"
CDS 156..638
/gene="PMP22"
/gene_synonym="CMT1A"
/gene_synonym="CMT1E"
/gene_synonym="DSS"
/gene_synonym="GAS-3"
/gene_synonym="HMSNIA"
/gene_synonym="HNPP"
/gene_synonym="MGC20769"
/gene_synonym="Sp110"
/codon_start=1
/product="peripheral myelin protein 22"
/protein_id="AAH91499.1"
/db_xref="GeneID:5376"
/db_xref="HGNC:HGNC:9118"
/db_xref="MIM:601097"
/translation="MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCST
SSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIF
QILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE
"
BASE COUNT 475 a 433 c 386 g 503 t
ORIGIN
1 caggcttagt ctgtcggctg cgggtctctg actgccctgt ggggagggtc ttgccttaac
61 atcccttgca tttggctgca aagaaatctg cttggaagaa ggggttacgc tgtttggccg
121 ggcagaaact ccgctgagca gaacttgccg ccagaatgct cctcctgttg ctgagtatca
181 tcgtcctcca cgtcgcggtg ctggtgctgc tgttcgtctc cacgatcgtc agccaatgga
241 tcgtgggcaa tggacacgca actgatctct ggcagaactg tagcacctct tcctcaggaa
301 atgtccacca ctgtttctca tcatcaccaa acgaatggct gcagtctgtc caggccacca
361 tgatcctgtc gatcatcttc agcattctgt ctctgttcct gttcttctgc caactcttca
421 ccctcaccaa ggggggcagg ttttacatca ctggaatctt ccaaattctt gctggtctgt
481 gcgtgatgag tgctgcggcc atctacacgg tgaggcaccc ggagtggcat ctcaactcgg
541 attactccta cggtttcgcc tacatcctgg cctgggtggc cttccccctg gcccttctca
601 gcggtgtcat ctatgtgatc ttgcggaaac gcgaatgagg cgcccagacg gtctgtctga
661 ggctctgagc gtacataggg aagggaggaa gggaaaccag aaagcagaca aagaaaaaag
721 agctagccca aaatcccaaa ctcaaaccaa accaaacaga aagcagtgga ggtgggggtt
781 gctgttgatt gaagatgtat ataatatctc cggtttataa aacctattta taacactttt
841 tacatatatg tacatagtat tgtttgcttt ttatgttgac catcagcctc gtgttgagcc
901 ttaaagaagt agctaaggaa ctttacatcc taacagtata atccagctca gtatttttgt
961 tttgtttttt gtttgtttgt tttgttttac ccagaaataa gataactcca tctcgcccct
1021 tccctttcat ctgaaagaag atacctccct cccagtccac ctcatttaga aaaccaaagt
1081 gtgggtagaa accccaaatg tccaaaagcc cttttctggt gggtgaccca gtgcatccaa
1141 cagaaacagc cgctgcccga acctgtgtga agctttacgc gcacacggac aaaatgccca
1201 aactggagcc cttgcaaaaa cacggcttgt ggcattggca tacttgccct tacaggtgga
1261 gtatcttcgt cacacatcta aatgagaaat cagtgacaac aagtctttga aatggtgcta
1321 tggatttacc attccttatt atcactaatc atctaaacaa ctcactggaa atccaattaa
1381 caattttaca acataagata gaatggagac ctgaataatt ctgtgtaata taaatggttt
1441 ataactgctt ttgtacctag ctaggctgct attattacta taatgagtaa atcataaagc
1501 cttcatcact cccacatttt tcttacggtc ggagcatcag aacaagcgtc tggactcctt
1561 gggaccgtga gttcctagag cttggctggg tctaggctgt tctgtgcctc caaggactgt
1621 ctggcaatga cttgtattgg ccaccaactg tagatgtata tatggtgccc ttctgatgct
1681 aagactccag accttttgtt tttgctttgc attttctgat tttataccaa ctgtgtggac
1741 taagatgcat taaaataaac atcagagtaa ctcaaaaaaa aaaaaaaaaa aaaaaaa
//