LOCUS BC091484 2523 bp mRNA linear HUM 07-MAR-2005
DEFINITION Homo sapiens F-box and leucine-rich repeat protein 4, mRNA (cDNA
clone MGC:111014 IMAGE:6178874), complete cds.
ACCESSION BC091484
VERSION BC091484.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2523)
AUTHORS Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2523)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. James R. Lupski
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 196 Row: a Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21536437.
FEATURES Location/Qualifiers
source 1..2523
/db_xref="H-InvDB:HIT000334334"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:111014 IMAGE:6178874"
/tissue_type="Peripheral Nervous System, dorsal root
ganglion"
/clone_lib="Lupski_dorsal_root_ganglion"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2523
/gene="FBXL4"
/gene_synonym="FBL4"
/gene_synonym="FBL5"
/db_xref="GeneID:26235"
/db_xref="MIM:605654"
CDS 430..2295
/gene="FBXL4"
/gene_synonym="FBL4"
/gene_synonym="FBL5"
/codon_start=1
/product="FBXL4 protein"
/protein_id="AAH91484.1"
/db_xref="GeneID:26235"
/db_xref="MIM:605654"
/translation="MSPVFPMLTVLTMFYYICLRRRARTATRGEMMNTHRAIESNSQT
SPLNAEVVQYAKEVVDFSSHYGSENSMSYTMWNLAGVPNVFPSSGDFTQTAVFRTYGT
WWDQCPSASLPFKRTPPNFQSQDYVELTFEQQVYPTAVHVLETYHPGAVIRILACSAN
PYSPNPPAEVRWEILWSERPTKVNASQARQFKPCIKQINFPTNLIRLEVNSSLLEYYT
ELDAVVLHGVKDKPVLSLKTSLIDMNDIEDDAYAEKDGCGMDSLNKKFSSAVLGEGPN
NGYFDKLPYELIQLILNHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLDD
TSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSHFLNETC
LEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFC
SELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLE
ELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDELACNCTRLQQLDI
LGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASFPKVFIKKSFTQ"
BASE COUNT 705 a 538 c 536 g 744 t
ORIGIN
1 cgggcttgcg gcggttgtgc cgcatctaga gagtcgggga gccgcccccg cacccaggcc
61 ttctcgcgct gcctggtcgc tggtgaagcc cgcggcgcgc gcctctcccg gaccctgcag
121 gatttttctt cctggcctgg ttcccttgcc ttctccattt gcttcattcg cttggatttt
181 caagaagctt tgaagctgga taggagtctc cagtcttcct cttgatccat atgtttcagg
241 taaaagaatg tcacatgtca gcatttgtac ctgaagtcag catgcaaagt tcagggtaca
301 tggatgaatg ccaacttttg catttcccat gtgtatcctg tgaccattct atctgggaac
361 atccttcaaa gagttcatgc atcttactga ggacacctga ccttttgaag cttcataatt
421 cacatctaga tgtcaccggt ctttcccatg ttaacagttc tgaccatgtt ttattatata
481 tgccttcggc gccgagccag gacagctaca agaggagaaa tgatgaacac ccatagagct
541 atagaatcaa acagccagac ttcccctctc aatgcagagg tagtccagta tgccaaagaa
601 gtagtggatt tcagttccca ttatggaagt gagaatagta tgtcctatac tatgtggaat
661 ttggctggtg taccaaatgt attcccaagt tctggtgact ttactcagac agctgtgttt
721 cgaacttatg ggacatggtg ggatcagtgt cctagtgctt ccttgccatt caagaggacg
781 ccacctaatt ttcagagcca ggactatgtg gaacttactt ttgaacaaca ggtgtatcct
841 acagctgtac atgttctaga aacctatcat cccggagcag tcattagaat tctcgcttgt
901 tctgcaaatc cttattcccc aaatccacca gctgaagtaa gatgggagat tctttggtca
961 gagagaccta cgaaggtgaa tgcttcccaa gctcgccagt ttaaaccttg tattaagcag
1021 ataaatttcc ccacaaatct tatacgactg gaagtaaata gttctcttct ggaatattac
1081 actgaattag atgcagttgt gctacatggt gtgaaggaca agccagtgct ttctctcaag
1141 acttcactta ttgacatgaa tgatatagaa gatgatgcct atgcagaaaa ggatggttgt
1201 ggaatggaca gtcttaacaa aaagtttagc agtgctgtcc tcggggaagg gccaaataat
1261 gggtattttg ataaactacc ttatgagctt attcagctga ttctgaatca tcttacacta
1321 ccagacctgt gtagattagc acagacttgc aaactactga gccagcattg ctgtgatcct
1381 ctgcaataca tccacctcaa tctgcaacca tactgggcaa aactagatga cacttctctg
1441 gaatttctac agtctcgctg cactcttgtc cagtggctta atttatcttg gactggcaat
1501 agaggcttca tctctgttgc aggatttagc aggtttctga aggtttgtgg atccgaatta
1561 gtacgccttg aattgtcttg cagccacttt cttaatgaaa cttgcttaga agttatttct
1621 gagatgtgtc caaatctaca ggccttaaat ctctcctcct gtgataagct accacctcaa
1681 gctttcaacc acattgccaa gttatgcagc cttaaacgac ttgttctcta tcgaacaaaa
1741 gtagagcaaa cagcactgct cagcattttg aacttctgtt cagagcttca gcacctcagt
1801 ttaggcagtt gtgtcatgat tgaagactat gatgtgatag ctagcatgat aggagccaag
1861 tgtaaaaaac tccggaccct ggatctgtgg agatgtaaga atattactga gaatggaata
1921 gcagaactgg cttctgggtg tccactactg gaggagcttg accttggctg gtgcccaact
1981 ctgcagagca gcaccgggtg cttcaccaga ctggcacacc agctcccaaa cttgcaaaaa
2041 ctctttctta cagctaatag atctgtgtgt gacacagaca ttgatgaatt ggcatgtaat
2101 tgtaccaggt tacagcagct ggacatatta ggaacaagaa tggtaagtcc ggcatcctta
2161 agaaaactcc tggaatcttg taaagatctt tctttacttg atgtgtcctt ctgttcgcag
2221 attgataaca gagctgtgct agaactgaat gcaagctttc caaaagtgtt cataaaaaag
2281 agctttactc agtgacttaa tatatgttct gtattaaaat taatgtgctt tgttggggtt
2341 taattttggg attggttttg ggttttgttt ttagttgttt taatggtaag aattaagaca
2401 tttgtagatt ttaaagaaaa atatgaaatt gtccattaaa tcaagtaaaa atgtgcacaa
2461 atgttttcat aaaatactgc aagcacttct cttcaaaaaa aaaaaaaaaa aaaaaaaaaa
2521 aaa
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