LOCUS BC090864 2778 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens karyopherin alpha 1 (importin alpha 5), mRNA (cDNA
clone MGC:102833 IMAGE:6173605), complete cds.
ACCESSION BC090864
VERSION BC090864.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2778)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2778)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 196 Row: a Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504894.
FEATURES Location/Qualifiers
source 1..2778
/db_xref="H-InvDB:HIT000334248"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:102833 IMAGE:6173605"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2778
/gene="KPNA1"
/gene_synonym="IPOA5"
/gene_synonym="NPI-1"
/gene_synonym="RCH2"
/gene_synonym="SRP1"
/db_xref="GeneID:3836"
/db_xref="HGNC:HGNC:6394"
/db_xref="MIM:600686"
CDS 160..1776
/gene="KPNA1"
/gene_synonym="IPOA5"
/gene_synonym="NPI-1"
/gene_synonym="RCH2"
/gene_synonym="SRP1"
/codon_start=1
/product="karyopherin alpha 1 (importin alpha 5)"
/protein_id="AAH90864.1"
/db_xref="GeneID:3836"
/db_xref="HGNC:HGNC:6394"
/db_xref="MIM:600686"
/translation="MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQL
FKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMIEMIFSKSPEQQLSA
TQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSL
QTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMYRDYVLDCNILPPLLQ
LFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACW
ALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVI
LNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA
EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENI
LRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTED
EDSSIAPQVDLNQQQYIFQQCEAPMEGFQL"
BASE COUNT 786 a 584 c 649 g 759 t
ORIGIN
1 cgctgctcgg tgcgaggcgg cggagagcga ggcctggtga gcaccgccga ggcgcgggcc
61 agctcttcga ggttgtgcgc gggagtggca cggcgggcgg gcgagcgagg ggctaacttc
121 agcggtggca ccgggatcgg ttgccttgag cctgaaatca tgaccacccc aggaaaagag
181 aactttcgcc tgaaaagtta caagaacaaa tctctgaatc ccgatgagat gcgcaggagg
241 agggaggaag aaggactgca gttacgaaag cagaaaagag aagagcagtt attcaagcgg
301 agaaatgttg ctacagcaga agaagaaaca gaagaagaag ttatgtcaga tggaggcttt
361 catgaggctc agattaataa catggagatg gcaccaggtg gtgtcatcac ttctgacatg
421 attgaaatga tattttccaa aagcccagag caacagcttt cagcaacaca gaaattcagg
481 aagctgcttt caaaagaacc taaccctcct attgatgaag ttatcagcac accaggagta
541 gtggccaggt ttgtggagtt cctcaaacga aaagagaatt gtacactgca gtttgaatca
601 gcttgggtac tgacaaatat tgcttcagga aattctcttc agacccgaat tgtgattcag
661 gcaggagctg tgcccatctt catagagttg ctcagctcag agtttgaaga tgtccaggaa
721 caggcagtct gggctcttgg caacattgct ggagatagta ccatgtacag ggactatgtc
781 ttagactgca atatccttcc ccctcttttg cagttatttt caaagcaaaa ccgcctgacc
841 atgacccgga atgcagtatg ggctttgtct aatctctgta gagggaaaag tccacctcca
901 gaatttgcaa aggtttctcc atgtctgaat gtgctttcct ggttgctgtt tgtcagtgac
961 actgatgtac tggctgatgc ctgctgggcc ctctcatatc tatcagatgg acccaatgat
1021 aaaattcaag cggtcatcga tgcgggagta tgtaggagac ttgtggaact gctgatgcat
1081 aatgattata aagtggtttc tcctgctttg cgagctgtgg gaaacattgt cacaggggat
1141 gatattcaga cacaggtaat tctgaattgc tcagctctgc agagtttatt gcatttgctg
1201 agtagcccaa aggaatctat caaaaaggaa gcatgttgga cgatatctaa tattacagct
1261 ggaaataggg cacagatcca gactgtgata gatgccaaca ttttcccagc cctcattagt
1321 attttacaaa ctgctgaatt tcggacaaga aaagaagcag cttgggccat cacaaatgca
1381 acttctggag gatcagctga acagatcaag tacctagtag aactgggttg tatcaagccg
1441 ctctgtgatc tcctcacggt catggactct aagattgtac aggttgccct aaatggcttg
1501 gaaaatatcc tgaggcttgg agaacaggaa gccaaaagga atggcactgg cattaaccct
1561 tactgtgctt tgattgaaga agcttatggt ctggataaaa ttgagttctt acagagtcat
1621 gaaaaccagg agatctacca aaaggccttt gatcttattg agcattactt cgggaccgaa
1681 gatgaagaca gcagcattgc accccaggtt gaccttaacc agcagcagta catcttccaa
1741 cagtgtgagg ctcctatgga aggtttccag ctttgaagca atactctgct ttcacgttcc
1801 tgtgtcagac caggctaccc agtcgagtcc tcttgtggag cccacagtcc tcatggagct
1861 aacttctcaa atgttttcca taatactgtt tgcgctcatt tgcttgcctt gcgcacctgc
1921 tctcttacac acatctggaa aacctccggc tctctgtggt ggaataccct tctaataaaa
1981 gggtaaccag aacggcccac tctcttttac ggaaaaatcc ctaggctttg gagatccgca
2041 cttacattag agttatggga atatacacat attaatgtgg ctcccttttt cttgtggggg
2101 aataaaagag gactcctcct cattcccttt aacatggggg aaaaaactga cattaaaaga
2161 tgagactaaa tctttatctt gaattttaca caactactta acgacaaggg agatgtttag
2221 acctgttgtg tatacttcag agtacttttc atgagttctt ccacagtgaa cccttggatt
2281 acctagtggc tttttctagc cagatttgca ttaatcctta ctgagattgg atggttttct
2341 ttcctctatt ggcgccattc ttcagatatt aaagttaaac catccactcc ctcaccttca
2401 gccttcagtg aatgtgcttt ctagttgtca ggaatgctga agaattaaca ctttgactcc
2461 taaatgtgat actggtttgt agattccctt agagcagaaa ggagaggggc acatattaat
2521 ttgtatcgct tttgcttctc tttggtcttt tgtgtcttag aatttggaag tggttcattt
2581 ctgttgctgg tatgaggatt tcgaatactt agtaatcgaa aaccatatcc tgtaatttaa
2641 taaaaaaaac taaggaagaa aaaaccctcc aattttccca aatgcaatca gtgtaactag
2701 gggctgtgtt tctgcattaa aataaatgtt tcaggctttg tggtcctgat caaggtcctc
2761 attaaaaaaa aaaaaaaa
//