LOCUS BC089042 5215 bp mRNA linear HUM 04-AUG-2006
DEFINITION Homo sapiens protein tyrosine phosphatase, non-receptor type 23,
mRNA (cDNA clone MGC:99484 IMAGE:6579163), complete cds.
ACCESSION BC089042
VERSION BC089042.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5215)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5215)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-JAN-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: n Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24308072.
FEATURES Location/Qualifiers
source 1..5215
/db_xref="H-InvDB:HIT000266222"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:99484 IMAGE:6579163"
/tissue_type="Ovary, teratocarcinoma"
/clone_lib="NIH_MGC_109"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..5215
/gene="PTPN23"
/gene_synonym="DKFZP564F0923"
/gene_synonym="HD-PTP"
/gene_synonym="HDPTP"
/gene_synonym="KIAA1471"
/gene_synonym="PTP-TD14"
/db_xref="GeneID:25930"
/db_xref="HGNC:HGNC:14406"
/db_xref="MIM:606584"
CDS 34..4944
/gene="PTPN23"
/gene_synonym="DKFZP564F0923"
/gene_synonym="HD-PTP"
/gene_synonym="HDPTP"
/gene_synonym="KIAA1471"
/gene_synonym="PTP-TD14"
/codon_start=1
/product="protein tyrosine phosphatase, non-receptor type
23"
/protein_id="AAH89042.1"
/db_xref="GeneID:25930"
/db_xref="HGNC:HGNC:14406"
/db_xref="MIM:606584"
/translation="MEAVPRMPMIWLDLKEAGDFHFQPAVKKFVLKNYGENPEAYNEE
LKKLELLRQNAVRVPRDFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSG
KSVAHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREH
FPQAYSVDMSRQILTLNVNLMLGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEAC
RALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSA
LDKLNEAIKLAKGQPDTVQDALRFTMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVK
GAPLVKPLPVNPTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNE
VLDQFMDSMQLDPETVDNLDAYSHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFT
DVEASLKDIRDLLEEDELLEQKFQEAVGQAGAISITSKAELAEVRREWAKYMEVHEKA
SFTNSELHRAMNLHVGNLRLLSGPLDQVRAALPTPALSPEDKAVLQNLKRILAKVQEM
RDQRVSLEQQLRELIQKDDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQD
RVLCALTEANVQYAAVRRVLSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADL
ESKVAALLERTQSTCQAREAARQQLLDRELKKKPPPRPTAPKPLLPRREESEAVEAGD
PPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSG
PTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPP
VAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPP
PQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPP
QQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAH
SGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSP
APSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKV
DAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRGQLGDVGALDTVWRELQDAQEH
DARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPYCPPLVAT
QAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSLAL
SSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHY
LHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHML
QEKLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQKNHLPQDSQDLVLGGDVP
ISSIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPL
PEAPQPKEEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHN
GQGLRATRPSDDPLSLLDPLWTLNKT"
BASE COUNT 1054 a 1796 c 1427 g 938 t
ORIGIN
1 ttcggcacga ggggccggcg ggtgccagcc gccatggagg ccgtgccccg catgcccatg
61 atctggctgg acctgaagga ggccggtgac tttcacttcc agccagctgt gaagaagttt
121 gtcctgaaga attatggaga gaacccagaa gcctacaatg aagaactgaa gaagctggag
181 ttgctcagac agaatgctgt ccgtgtccca cgagactttg agggctgtag tgtcctccgc
241 aagtacctcg gccagcttca ttacctgcag agtcgggtcc ccatgggctc gggccaggag
301 gccgctgtcc ctgtcacctg gacagagatc ttctcaggca agtctgtggc ccatgaggac
361 atcaagtacg agcaggcctg tattctctac aaccttggag cgctgcactc catgctgggg
421 gccatggaca agcgggtgtc tgaggagggc atgaaggtct cctgtaccca tttccagtgc
481 gcagccggcg ccttcgccta cctacgggag cacttccctc aagcctacag cgtcgacatg
541 agccgccaga tccttacgct caacgtcaac ctcatgctgg gccaggctca ggagtgcctc
601 ctggagaagt cgatgttgga caacaggaag agctttctgg tggcccgcat cagtgcacag
661 gtggtagatt actacaagga ggcatgccgg gccttggaga accccgacac tgcctcactg
721 ctgggccgga tccagaagga ctggaagaaa cttgtgcaga tgaagatcta ctacttcgca
781 gccgtggctc atctgcacat gggaaagcag gccgaggagc agcagaagtt cggggagcgg
841 gttgcatact tccagagcgc cctggacaag ctcaatgaag ccatcaagtt ggccaagggc
901 cagcctgaca ctgtgcaaga cgcgcttcgc ttcactatgg atgtcattgg gggaaagtac
961 aattctgcca agaaggacaa cgacttcatt taccatgagg ctgtcccagc attggacacc
1021 cttcagcctg taaaaggagc ccccttggtg aagcccttgc cagtgaaccc cacagaccca
1081 gctgttacag gccctgacat ctttgccaaa ctggtaccca tggctgccca cgaggcctcg
1141 tcactgtaca gtgaggagaa ggccaagctg ctccgggaga tgatggccaa gattgaggac
1201 aagaatgagg tcctggacca gttcatggat tcaatgcagt tggatcccga gacggtggac
1261 aaccttgatg cctacagcca catcccaccc cagctcatgg agaagtgcgc ggctctcagc
1321 gtccggcccg acactgtcag gaaccttgta cagtccatgc aagtgctgtc aggtgtgttc
1381 acggatgtgg aggcttccct gaaggacatc agagatctgt tggaggagga tgagctgcta
1441 gagcagaagt ttcaggaggc ggtgggccag gcaggggcca tctccatcac ctccaaggct
1501 gagctggcag aggtgaggcg agaatgggcc aagtacatgg aagtccatga gaaggcctcc
1561 ttcaccaaca gtgagctgca ccgtgccatg aacctgcacg tcggcaacct gcgcctgctc
1621 agcgggccgc ttgaccaggt ccgggctgcc ctgcccacac cggccctctc cccagaggac
1681 aaggccgtgc tgcaaaacct aaagcgcatc ctggctaagg tgcaggagat gcgggaccag
1741 cgcgtgtccc tggagcagca gctgcgtgag cttatccaga aagatgacat cactgcctcg
1801 ctggtcacca cagaccactc agagatgaag aagttgttcg aggagcagct gaaaaagtat
1861 gaccagctga aggtgtacct ggagcagaac ctggccgccc aggaccgtgt cctctgtgca
1921 ctgacagagg ccaacgtgca gtacgcagcc gtgcggcggg tactcagcga cttggaccaa
1981 aagtggaact ccacgctgca gaccctggtg gcctcgtatg aagcctatga ggacctgatg
2041 aagaagtcgc aggagggcag ggacttctac gcagatctgg agagcaaggt ggctgctctg
2101 ctggagcgca cgcagtccac ctgccaggcc cgcgaggctg cccgccagca gctcctggac
2161 agggagctga agaagaagcc gccgccacgg cccacagccc caaagccgct gctgccccgc
2221 agggaggaga gtgaggcagt ggaagcagga gacccccctg aggagctgcg cagcctcccc
2281 cctgacatgg tggctggccc acgactgcct gacaccttcc tgggaagtgc caccccgctc
2341 cactttcctc ccagcccctt ccccagctcc acaggcccag gaccccacta tctctcaggc
2401 cccttgcccc ctggtaccta ctcgggcccc acccagctga tacagcccag ggccccaggg
2461 ccccatgcaa tgcccgtagc acctgggcct gccctctacc cagcccctgc ctacacaccg
2521 gagctgggcc ttgtgccccg atcctcccca cagcatggcg tggtgagcag tccctatgtg
2581 ggggtagggc cggccccacc agttgcaggt ctcccctcgg ccccacctcc tcaattctca
2641 ggccccgagt tggccatggc ggttcggcca gccaccacca cagtagatag catccaggcg
2701 cccatcccca gccacacagc cccacggcca aaccccaccc ctgctcctcc cccgccctgc
2761 ttccctgtgc ccccaccgca gccactgccc acgccttaca cctaccctgc aggggctaag
2821 caacccatcc cagcacagca ccacttctct tctgggatcc ccgcaggttt tccagcccca
2881 aggattgggc cccagcccca gccccatcct cagccccatc cttcacaagc gtttgggcct
2941 cagcccccac agcagcccct tccactccag catccacatc tcttcccacc ccaggcccca
3001 ggactcctac ccccacaatc cccctacccc tatgcccctc agcctggggt cctggggcag
3061 ccgccacccc ccctacacac ccagctctac ccaggtcccg ctcaagaccc tctgccagcc
3121 cactcagggg ctctgccttt ccccagccct gggccccctc agcctcccca tcccccactg
3181 gcatatggtc ctgccccttc taccagaccc atgggccccc aggcagcccc tcttaccatt
3241 cgagggccct cgtctgctgg ccagtccacc cctagtcccc acctggtgcc ttcacctgcc
3301 ccatctccag ggcctggtcc ggtaccccct cgccccccag cagcagaacc acccccttgc
3361 ctgcgccgag gcgccgcagc tgcagacctg ctctcctcca gcccggagag ccagcatggc
3421 ggcactcagt ctcctggggg tgggcagccc ctgctgcagc ccaccaaggt ggatgcagct
3481 gagggtcgtc ggccgcaggc cctgcggctg attgagcggg acccctatga acatcctgag
3541 aggctgcggc agttgcagca ggagctggag gcctttcggg gtcagctggg ggatgtggga
3601 gctctggaca ctgtctggcg agagctgcaa gatgcgcagg aacatgatgc ccgaggccgt
3661 tccatcgcca ttgcccgctg ctactcactg aagaaccggc accaggatgt catgccctat
3721 gacagtaacc gtgtggtgct gcgctcaggc aaggatgact acatcaatgc cagctgcgtg
3781 gaggggctct ccccatactg ccccccgcta gtggcaaccc aggccccact gcctggcaca
3841 gctgctgact tctggctcat ggtccatgag cagaaagtgt cagtcattgt catgctggtt
3901 tctgaggctg agatggagaa gcaaaaagtg gcacgctact tccccaccga gaggggccag
3961 cccatggtgc acggtgccct gagcctggca ttgagcagcg tccgcagcac cgaaacccat
4021 gtggagcgcg tgctgagcct gcagttccga gaccagagcc tcaagcgctc tcttgtgcac
4081 ctgcacttcc ccacttggcc tgagttaggc ctgcccgaca gccccagcaa cttgctgcgc
4141 ttcatccagg aggtgcacgc acattacctg catcagcggc cgctgcacac gcccatcatt
4201 gtgcactgca gctctggtgt gggccgcacg ggagcctttg cactgctcta tgcagctgtg
4261 caggaggtgg aggctgggaa cggaatccct gagctgcctc agctggtgcg gcgcatgcgg
4321 cagcagagaa agcacatgct gcaggagaag ctgcacctca ggttctgcta tgaggcagtg
4381 gtgagacacg tggagcaggt cctgcagcgc catggtgtgc ctcctccatg caaacccttg
4441 gccagtgcaa gcatcagcca gaagaaccac cttcctcagg actcccagga cctggtcctc
4501 ggtggggatg tgcccatcag ctccatccag gccaccattg ccaagctcag cattcggcct
4561 cctggggggt tggagtcccc ggttgccagc ttgccaggcc ctgcagagcc cccaggcctc
4621 ccgccagcca gcctcccaga gtctacccca atcccatctt cctccccacc ccccctttcc
4681 tccccactac ctgaggctcc ccagcctaag gaggagccgc cagtgcctga agcccccagc
4741 tcggggcccc cctcctcctc cctggaattg ctggcctcct tgaccccaga ggccttctcc
4801 ctggacagct ccctgcgggg caaacagcgg atgagcaagc ataactttct gcaggcccat
4861 aacgggcaag ggctgcgggc cacccggccc tctgacgacc ccctcagcct tctggatcca
4921 ctctggacac tcaacaagac ctgaacaggt tttgcctacc tggtccttac actacatcat
4981 catcatctca tgcccacctg cccacaccca gcagagcttc tcagtgggca cagtctctta
5041 ctcccatttc tgctgccttt ggccctgcct ggcccagcct gcacccctgt ggggtggaaa
5101 tgtactgcag gctctgggtc aggttctgct cctttatggg acccgacatt tttcagctct
5161 ttgctattga aataataaac caccctgttc tgtggccaaa aaaaaaaaaa aaaaa
//