LOCUS BC082244 1397 bp mRNA linear HUM 19-APR-2005
DEFINITION Homo sapiens PH domain and leucine rich repeat protein phosphatase,
mRNA (cDNA clone IMAGE:4641238), partial cds.
ACCESSION BC082244
VERSION BC082244.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1397)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1397)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-SEP-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: d Column: 19.
FEATURES Location/Qualifiers
source 1..1397
/db_xref="H-InvDB:HIT000265961"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4641238"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..>1397
/gene="PHLPP"
/gene_synonym="PLEKHE1"
/gene_synonym="SCOP"
/db_xref="GeneID:23239"
CDS <1..>1397
/gene="PHLPP"
/gene_synonym="PLEKHE1"
/gene_synonym="SCOP"
/codon_start=1
/product="PHLPP protein"
/protein_id="AAH82244.1"
/db_xref="GeneID:23239"
/translation="EVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIR
KLIADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEVLHCERNQLVTLDICGYFLKALY
ASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARL
FCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNAS
ANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFP
ASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCV
DLSCNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLNNIRCFKIDQPSTGDAS
GAPAVWSHGYTEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMS
DILAEELQKTKKKKK"
BASE COUNT 417 a 314 c 317 g 349 t
ORIGIN
1 gaagtattgg agaaattgac tgctgtggat aaactttgta tgtctggaaa ctgtgtggag
61 acccttaggc tacaggcttt aagaaaaatg cctcacatta aacatgtgga tctaaggttg
121 aacgtaatta ggaagctgat agcagatgaa gtggactttc tacagcatgt tactcagctt
181 gacctacgag acaataagct tggtgatcta gatgctatga ttttcaacaa cattgaagtt
241 ttacactgtg aaaggaatca actggtcaca ttagacatct gtggctattt cctaaaagcg
301 ctctatgcct cttctaatga acttgttcaa cttgatgttt acccagttcc aaattatctg
361 tcctacatgg atgtttcaag gaaccgctta gaaaatgtgc ctgagtgggt atgtgaaagc
421 cgaaagctag aagttttgga tattggccat aatcaaatat gtgaacttcc tgcccgctta
481 ttttgtaata gcagtctccg gaaactactg gcaggacaca accagttggc aaggctgcct
541 gaaaggctag aaagaacctc ggtggaggtc ttggatgtgc aacacaacca gctccttgag
601 ctcccaccta accttctgat gaaggctgac agcctgagat tcctgaacgc ctctgcgaac
661 aaactggaaa gccttcctcc agccacgctt tccgaagaga caaacagtat cttacaagag
721 ttgtatttga caaataacag cctcacagac aaatgtgtgc ccttgttaac gggacacccc
781 catttgaaga tccttcacat ggcctataac cgacttcaga gttttccagc aagtaaaatg
841 gcgaaactgg aggaacttga agaaattgat ctcagtggga ataagctgaa agccatccca
901 acaacgatca tgaattgcag gcgcatgcac accgtgattg ctcactccaa ctgcatcgag
961 gtctttcccg aagttatgca gctcccagag atcaagtgtg tggacctgag ctgtaatgag
1021 ctaagtgaag tcacattacc agaaaacctg cctcccaaac tgcaggagct agacctgact
1081 ggaaacccgc gccttgtcct tgatcacaaa accctggaac tactgaataa tatccgctgt
1141 ttcaagattg atcagccttc tacaggagac gcttccggag ccccagctgt atggagtcat
1201 ggttacactg aagcttcggg ggtaaaaaac aagttgtgtg tcgcagccct gtcggtgaat
1261 aacttctgtg acaaccgcga agccctgtat ggtgtgtttg acggagaccg gaatgtggag
1321 gtgccctacc ttctccagtg cactatgagt gacattttgg ctgaagagct gcaaaaaaca
1381 aaaaaaaaaa aaaaaaa
//