LOCUS BC082238 2700 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens basic helix-loop-helix family, member e40, mRNA (cDNA
clone MGC:99681 IMAGE:4860809), complete cds.
ACCESSION BC082238
VERSION BC082238.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2700)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2700)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-SEP-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: d Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4503298.
FEATURES Location/Qualifiers
source 1..2700
/db_xref="H-InvDB:HIT000265955"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:99681 IMAGE:4860809"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2700
/gene="BHLHE40"
/gene_synonym="DEC1"
/gene_synonym="SHARP-2"
/gene_synonym="Stra14"
/db_xref="GeneID:8553"
/db_xref="HGNC:HGNC:1046"
/db_xref="MIM:604256"
CDS 182..1420
/gene="BHLHE40"
/gene_synonym="DEC1"
/gene_synonym="SHARP-2"
/gene_synonym="Stra14"
/codon_start=1
/product="basic helix-loop-helix family, member e40"
/protein_id="AAH82238.1"
/db_xref="GeneID:8553"
/db_xref="HGNC:HGNC:1046"
/db_xref="MIM:604256"
/translation="MERIPSAQPPPACLPKAPGLEHGDLPGMYPAHMYQVYKSRRGIK
RSEDSKETYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLK
HVKALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKH
ENTRDLKSSQLVTHLHRVVSELLQGGTSRKPSDPAPKVMDFKEKPSSPAKGSEGPGKN
CVPVIQRTFAHSSGEQSGSDTDTDSGYGGESEKGDLRSEQPCFKSDHGRRFTMGERIG
AIKQESEEPPTKKNRMQLSDDEGHFTSSDLISSPFLGPHPHQPPFCLPFYLIPPSATA
YLPMLEKCWYPTSVPVLYPGLNASAAALSSFMNPDKISAPLLMPQRLPSPLPAHPSVD
SSVLLQALKPIPPLNLETKD"
BASE COUNT 685 a 727 c 668 g 620 t
ORIGIN
1 cacgccccca actgaagctg catctcaaag ccgaagattc cagcagccca ggggatttca
61 aagagctcag actcagagga acatctgcgg agagaccccc gaagccctct ccagggcagt
121 cctcatccag acgctccgct agtgcagaca ggagcgcgca gtggccccgg ctcgccgcgc
181 catggagcgg atccccagcg cgcaaccacc ccccgcctgc ctgcccaaag caccgggact
241 ggagcacgga gacctaccag ggatgtaccc tgcccacatg taccaagtgt acaagtcaag
301 acggggaata aagcggagcg aggacagcaa ggagacctac aaattgccgc accggctcat
361 cgagaaaaag agacgtgacc ggattaacga gtgcatcgcc cagctgaagg atctcctacc
421 cgaacatctc aaacttacaa ctttgggtca cttggaaaaa gcagtggttc ttgaacttac
481 cttgaagcat gtgaaagcac taacaaacct aattgatcag cagcagcaga aaatcattgc
541 cctgcagagt ggtttacaag ctggtgagct gtcagggaga aatgtcgaaa caggtcaaga
601 gatgttctgc tcaggtttcc agacatgtgc ccgggaggtg cttcagtatc tggccaagca
661 cgagaacact cgggacctga agtcttcgca gcttgtcacc cacctccacc gggtggtctc
721 ggagctgctg cagggtggta cctccaggaa gccatcagac ccagctccca aagtgatgga
781 cttcaaggaa aaacccagct ctccggccaa aggttcggaa ggtcctggga aaaactgcgt
841 gccagtcatc cagcggactt tcgctcactc gagtggggag cagagcggca gcgacacgga
901 cacagacagt ggctatggag gagaatcgga gaagggcgac ttgcgcagtg agcagccgtg
961 cttcaaaagt gaccacggac gcaggttcac gatgggagaa aggatcggcg caattaagca
1021 agagtccgaa gaacccccca caaaaaagaa ccggatgcag ctttcggatg atgaaggcca
1081 tttcactagc agtgacctga tcagctcccc gttcctgggc ccacacccac accagcctcc
1141 tttctgcctg cccttctacc tgatcccacc ttcagcgact gcctacctgc ccatgctgga
1201 gaagtgctgg tatcccacct cagtgccagt gctataccca ggcctcaacg cctctgccgc
1261 agccctctct agcttcatga acccagacaa gatctcggct cccttgctca tgccccagag
1321 actcccttct cccttgccag ctcatccgtc cgtcgactct tctgtcttgc tccaagctct
1381 gaagccaatc ccccctttaa acttagaaac caaagactaa actctctagg ggatcctgct
1441 gctttgcttt ccttcctcgc tacttcctaa aaagcaacaa aaaagttttt gtgaatgctg
1501 caagattgtt gcattgtgta tactgagata atctgaggca tggagagcag attcagggtg
1561 tgtgtgtgtg tgtgtgtgtg tgtgtgtgta tgtgcgtgtg cgtgcacatg tgtgcctgcg
1621 tgttggtata ggactttaaa gctccttttg gcatagggaa gtcacgaagg attgcttgac
1681 atcaggagac ttggggggga ttgtagcaga cgtctgggct tttccccacc cagagaatag
1741 cccccttcga tacacatcag ctggattttc aaaagcttca aagtcttggt ctgtgagtca
1801 ctcttcagtt tgggagctgg gtctgtggct ttgatcagaa ggtactttca aaagagggct
1861 ttccagggct cagctcccaa ccagctgtta ggaccccacc cttttgcctt tattgtcgac
1921 gtgactcacc agacgtcggg gagagagagc agtcagaccg agctttctgc taacatgggg
1981 aggtagcagg cactggcata gcacggtagt ggtttgggga ggtttccgca ggtctgctcc
2041 ccacccctgc ctcggaagaa taaagagaat gtagttccct actcaggctt tcgtagtgat
2101 tagcttacta aggaactgaa aatgggcccc ttgtacaagc tgagctgccc cggagggagg
2161 gaggagttcc ctgggcttct ggcacctgtt tctaggccta accattagta cttactgtgc
2221 agggaaccaa accaaggtct gagaaatgcg gacaccccga gcgagcaccc caaagtgcac
2281 aaagctgagt aaaaagctgc ccccttcaaa cagaactaga ctcagttttc aattccatcc
2341 taaaactcct tttaaccaag cttagcttct caaaggccta accaagcctt ggcaccgcca
2401 gatcctttct gtaggctaat tcctcttgcc caacggcata tggagtgtcc ttattgctaa
2461 aaaggattcc gtctccttca aagaagtttt atttttggtc cagagtactt gttttcccga
2521 tgtgtccagc cagctccgca gcagcttttc aaaatgcact atgcctgatt gctgatcgtg
2581 ttttaacttt ttcttttcct gtttttattt tggtattaag tcgttgcctt tatttgtaaa
2641 gctgttataa atatatatta tataaatata ttaaaaagga aaaaaaaaaa aaaaaaaaaa
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