LOCUS BC080596 2891 bp mRNA linear HUM 02-JUL-2005
DEFINITION Homo sapiens Rho guanine nucleotide exchange factor (GEF) 10-like,
mRNA (cDNA clone IMAGE:4589063), partial cds.
ACCESSION BC080596
VERSION BC080596.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2891)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2891)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-AUG-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: c Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33354274.
FEATURES Location/Qualifiers
source 1..2891
/db_xref="H-InvDB:HIT000265862"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4589063"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2891
/gene="ARHGEF10L"
/gene_synonym="FLJ10521"
/db_xref="GeneID:55160"
CDS <1..2662
/gene="ARHGEF10L"
/gene_synonym="FLJ10521"
/codon_start=2
/product="ARHGEF10L protein"
/protein_id="AAH80596.1"
/db_xref="GeneID:55160"
/translation="GDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPAFLEF
LKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTELET
LAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLTSGQRQLLLCETLTETVYGDRGQ
LIKSKERRVFLLNDMLVCANINFKPANHRGQLEISSLVPLGPKYVVKWNTALPQVQVV
EVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGPPRLFQELQDLQKDLAVVEQI
TLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKPDKSGR
PISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILAC
CIPAFSSRALSLQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFS
LNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICLGLQDG
SILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGVLWD
LESPPVCLTVGPGPVRTLLSLEDAVWASCGPRVTVLEATTLQPQQSFEAHQDEAVSVT
HMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIATRTTFLLPGQKHLCVTSLLICQ
GLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFLAVATSILAPDILRS
DQEEAEGPRAEEDKPDGQAHEPMPDSHVGRELTRKKGILLQYRLRSTAHLPGPLLSMR
EPAPADGAALEHSEEDGSIYEMADDPDVWVRSRPCARDAHRKEICSVAIISGGQGYRN
FGSALGSSGRQAPCGETDSTLLIWQVPLML"
BASE COUNT 615 a 922 c 852 g 502 t
ORIGIN
1 cggggacctc ttcgtggcct cgttttccaa gtccatggtg ctagatgtgt acagtgacta
61 cgtgaacaac ttcaccagtg ccatgtccat catcaagaag gcctgcctca ccaagcctgc
121 cttcctcgag ttcctcaagc gacggcaggt gtgcagccca gaccgtgtca ccctctacgg
181 gctgatggtc aagcccatcc agaggttccc acagttcata ctcctgcttc aggacatgct
241 gaagaacacc cccaggggcc atccggacag gctgtcgctg cagctggccc tcacagagct
301 ggagacgctg gctgagaagc tgaacgagca gaagcggctg gctgaccagg tggctgagat
361 ccagcagctg accaagagcg tcagtgaccg cagcagcctc aacaagctgt tgacctcagg
421 ccagcggcag ctgctcctgt gtgagacgtt gacggagacc gtgtacggtg accgcgggca
481 gctaattaag tccaaggagc gtcgggtctt cctgctcaac gacatgcttg tctgtgccaa
541 catcaacttc aagcctgcca accacagggg ccagctggag atcagcagcc tggtgcccct
601 ggggcccaag tatgtggtga agtggaacac ggcgctgccc caggtgcagg tggtggaggt
661 gggccaggac ggtggcacct atgacaagga caatgtgctc atccagcact caggcgccaa
721 gaaggcctct gcctcagggc aggctcagaa taaggtgtac ctcggccccc cacgcctctt
781 ccaggagctg caggacctgc agaaggacct ggccgtggtg gagcagatca cgcttctcat
841 cagcacgctg cacggcacct accagaacct gaacatgact gtggctcaag actggtgcct
901 ggccctgcag aggctgatgc gggtgaagga ggaagagatc cactcggcca acaagtgccg
961 tctcaggctc ctgcttcctg ggaaacccga caagtccggc cgccccatta gcttcatggt
1021 ggttttcatc acccccaacc ccctgagcaa gatttcctgg gtcaacaggt tacatttggc
1081 caaaatcgga ctccgggagg agaaccagcc aggctggcta tgcccggatg aggacaagaa
1141 gagcaaagcc ccattctggt gcccgatcct ggcctgctgc atccctgcct tctcctcccg
1201 ggcactcagc ctgcagcttg gggccctggt ccacagtcct gtcaactgtc ccctgctggg
1261 tttctcagca gtcagcacct cccttccaca gggctacctc tgggtcgggg gcggacagga
1321 aggcgcaggg ggccaggtgg aaatcttttc cttgaaccgg ccctcgcccc gcaccgtcaa
1381 gtccttccca ctggcagccc ctgtgctctg catggagtat atcccggagc tggaggagga
1441 ggcggagagc agagacgaga gcccgacagt tgctgacccc tcggccacgg tgcatccaac
1501 catctgcctc gggctccagg atggcagcat cctcctctac agcagtgtgg acactggcac
1561 ccagtgcctg gtgagctgca ggagcccagg tctgcagcct gtgctctgcc tgcgacacag
1621 ccccttccac ctgctcgctg gcctgcagga tgggaccctt gctgcttacc ctcggaccag
1681 cggaggtgtc ctgtgggacc tggagagccc tcccgtgtgc ctgactgtgg ggcccgggcc
1741 tgtccgcacc ctgttgagcc tggaggatgc cgtgtgggcc agctgtgggc cccgggtcac
1801 tgtcctggaa gccaccaccc tgcagcctca gcaaagcttc gaggcgcacc aggacgaggc
1861 agtgagcgtg acacacatgg tgaaggcggg cagcggcgtc tggatggcct tctcctccgg
1921 cacctccatc cgcctcttcc acactgagac cctggagcat ctgcaagaga tcaacatcgc
1981 caccaggacc accttcctcc tgccaggcca gaagcacttg tgtgtcacca gcctcctgat
2041 ctgccagggt ctgctctggg tgggcactga ccagggtgtc atcgtcctgc tgcccgtgcc
2101 tcggctggaa ggcatcccca agatcacagg gaaaggcatg gtctcactca atgggcactg
2161 tgggcctgtg gccttcctgg ctgtggctac cagcatcctg gcccctgaca tcctgcggag
2221 tgaccaggag gaggctgagg ggccccgggc tgaggaggac aagccagacg ggcaggcaca
2281 cgagcccatg cccgacagcc acgtgggccg agagctgacc cgcaagaagg gcatcctctt
2341 gcagtaccgc ctgcgctcca ccgcacacct cccgggcccg ctgctctcca tgcgggagcc
2401 ggcgcctgct gatggcgcag ctttggagca cagcgaggag gacggctcca tttacgagat
2461 ggccgacgac cccgacgtct gggtgcgcag ccggccctgc gcccgcgacg cccaccgcaa
2521 ggagatttgc tctgtggcca tcatctccgg cgggcagggc taccgcaact ttggcagcgc
2581 tctgggcagc agtgggaggc aggccccgtg tggggagacg gacagcaccc tcctcatctg
2641 gcaggtgccc ttgatgctat agcgcctccc ctctcccctc agagggcaca gctgcaggcc
2701 tgaccaaggc cacgcccggc tctcgtgctc taggacctgc acgggacttg tggatgggcc
2761 tggactctcc agaaactact tgggccagag caaaggaaaa cctcttgttt taaaaaaaaa
2821 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2881 aaaaaaaaaa a
//