LOCUS BC080581 1244 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aurora kinase B, mRNA (cDNA clone MGC:99661
IMAGE:2819846), complete cds.
ACCESSION BC080581
VERSION BC080581.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1244)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1244)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-AUG-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 59 Row: a Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4759177.
FEATURES Location/Qualifiers
source 1..1244
/db_xref="H-InvDB:HIT000265849"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:99661 IMAGE:2819846"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1244
/gene="AURKB"
/gene_synonym="AIK2"
/gene_synonym="AIM-1"
/gene_synonym="AIM1"
/gene_synonym="ARK2"
/gene_synonym="AurB"
/gene_synonym="IPL1"
/gene_synonym="STK5"
/db_xref="GeneID:9212"
/db_xref="HGNC:HGNC:11390"
/db_xref="MIM:604970"
CDS 54..1088
/gene="AURKB"
/gene_synonym="AIK2"
/gene_synonym="AIM-1"
/gene_synonym="AIM1"
/gene_synonym="ARK2"
/gene_synonym="AurB"
/gene_synonym="IPL1"
/gene_synonym="STK5"
/codon_start=1
/product="aurora kinase B"
/protein_id="AAH80581.1"
/db_xref="GeneID:9212"
/db_xref="HGNC:HGNC:11390"
/db_xref="MIM:604970"
/translation="MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSR
SNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFI
VALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRG
ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIAD
FGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESA
SHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRV
LPPSALQSVA"
BASE COUNT 295 a 348 c 330 g 271 t
ORIGIN
1 gggagagtag cagtgccttg gaccccagct ctcctccccc tttctctcta aggatggccc
61 agaaggagaa ctcctacccc tggccctacg gccgacagac ggctccatct ggcctgagca
121 ccctgcccca gcgagtcctc cggaaagagc ctgtcacccc atctgcactt gtcctcatga
181 gccgctccaa tgtccagccc acagctgccc ctggccagaa ggtgatggag aatagcagtg
241 ggacacccga catcttaacg cggcacttca caattgatga ctttgagatt gggcgtcctc
301 tgggcaaagg caagtttgga aacgtgtact tggctcggga gaagaaaagc catttcatcg
361 tggcgctcaa ggtcctcttc aagtcccaga tagagaagga gggcgtggag catcagctgc
421 gcagagagat cgaaatccag gcccacctgc accatcccaa catcctgcgt ctctacaact
481 atttttatga ccggaggagg atctacttga ttctagagta tgccccccgc ggggagctct
541 acaaggagct gcagaagagc tgcacatttg acgagcagcg aacagccacg atcatggagg
601 agttggcaga tgctctaatg tactgccatg ggaagaaggt gattcacaga gacataaagc
661 cagaaaatct gctcttaggg ctcaagggag agctgaagat tgctgacttc ggctggtctg
721 tgcatgcgcc ctccctgagg aggaagacaa tgtgtggcac cctggactac ctgcccccag
781 agatgattga ggggcgcatg cacaatgaga aggtggatct gtggtgcatt ggagtgcttt
841 gctatgagct gctggtgggg aacccaccct ttgagagtgc atcacacaac gagacctatc
901 gccgcatcgt caaggtggac ctaaagttcc ccgcttctgt gcccacggga gcccaggacc
961 tcatctccaa actgctcagg cataacccct cggaacggct gcccctggcc caggtctcag
1021 cccacccttg ggtccgggcc aactctcgga gggtgctgcc tccctctgcc cttcaatctg
1081 tcgcctgatg gtccctgtca ttcactcggg tgcgtgtgtt tgtatgtctg tgtatgtata
1141 ggggaaagaa gggatcccta actgttccct tatctgtttt ctacctcctc ctttgtttaa
1201 taaaggctga agctttttgt aaaaaaaaaa aaaaaaaaaa aaaa
//