LOCUS BC078180 2540 bp mRNA linear HUM 27-JUL-2004
DEFINITION Homo sapiens interferon induced with helicase C domain 1, mRNA
(cDNA clone IMAGE:6502757), partial cds.
ACCESSION BC078180
VERSION BC078180.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2540)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2540)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (19-JUL-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 174 Row: p Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27886567.
FEATURES Location/Qualifiers
source 1..2540
/db_xref="H-InvDB:HIT000265739"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6502757"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..>2540
/gene="IFIH1"
/gene_synonym="Hlcd"
/gene_synonym="MDA-5"
/gene_synonym="MDA5"
/db_xref="GeneID:64135"
/db_xref="MIM:606951"
CDS 224..>2540
/gene="IFIH1"
/gene_synonym="Hlcd"
/gene_synonym="MDA-5"
/gene_synonym="MDA5"
/codon_start=1
/product="IFIH1 protein"
/protein_id="AAH78180.1"
/db_xref="GeneID:64135"
/db_xref="MIM:606951"
/translation="MSNGYSTDENFRYLISCFRARVKMYIQVEPVLDYLTFLPAEVKE
QIQRTVATSGNMQAVELLLSTLEKGVWHLGWTREFVEALRRTGSPLAARYMNPELTDL
PSPSFENAHDEYLQLLNLLQPTLVDKLLVRDVLDKCMEEELLTIEDRNRIAAAENNGN
ESGVRELLKRIVQKENWFSAFLNVLRQTGNNELVQELTGSDCSESNAEIENLSQVDGP
QVEEQLLSTTVQPNLEKEVWGMENNSSESSFADSSVVSESDTSLAEGSVSCLDESLGH
NSNMGSDSGTMGSDSDEENVAARASPEPELQLRPYQMEVAQPALEGKNIIICLPTGSG
KTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSG
DTQLKISFPEVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNK
EAVYNNIMRHYLMQKLKNNRLKKENKPVIPLPQILGLTASPGVGGATKQAKAEEHILK
LCANLDAFTIKTVKENLDQLKNQIQEPCKKFAIADATREDPFKEKLLEIMTRIQTYCQ
MSPMSDFGTQPYEQWAIQMEKKAAKEGNRKERVCAEHLRKYNEALQINDTIRMIDAYT
HLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDEDDLKKPLKLDETDRFLMTLFFE
NNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITE
NEKFAEVGVKAHHLIGAGHSSEFKPMTQKKKK"
BASE COUNT 830 a 530 c 591 g 589 t
ORIGIN
1 cgccccgctg cccacctgcc cgcctgccca cctgcccagg tgcgagtgca gccccgcgcg
61 ccggcctgag agccctgtgg acaacctcgt cattgtcagg cacagagcgg tagaccctgc
121 ttctctaagt gggcagcgga cagcggcacg cacatttcac ctgtcccgca gacaacagca
181 ccatctgctt gggagaaccc tctcccttct ctgagaaaga aagatgtcga atgggtattc
241 cacagacgag aatttccgct atctcatctc gtgcttcagg gccagggtga aaatgtacat
301 ccaggtggag cctgtgctgg actacctgac ctttctgcct gcagaggtga aggagcagat
361 tcagaggaca gtcgccacct ccgggaacat gcaggcagtt gaactgctgc tgagcacctt
421 ggagaaggga gtctggcacc ttggttggac tcgggaattc gtggaggccc tccggagaac
481 cggcagccct ctggccgccc gctacatgaa ccctgagctc acggacttgc cctctccatc
541 gtttgagaac gctcatgatg aatatctcca actgctgaac ctccttcagc ccactctggt
601 ggacaagctt ctagttagag acgtcttgga taagtgcatg gaggaggaac tgttgacaat
661 tgaagacaga aaccggattg ctgctgcaga aaacaatgga aatgaatcag gtgtaagaga
721 gctactaaaa aggattgtgc agaaagaaaa ctggttctct gcatttctga atgttcttcg
781 tcaaacagga aacaatgaac ttgtccaaga gttaacaggc tctgattgct cagaaagcaa
841 tgcagagatt gagaatttat cacaagttga tggtcctcaa gtggaagagc aacttctttc
901 aaccacagtt cagccaaatc tggagaagga ggtctggggc atggagaata actcatcaga
961 atcatctttt gcagattctt ctgtagtttc agaatcagac acaagtttgg cagaaggaag
1021 tgtcagctgc ttagatgaaa gtcttggaca taacagcaac atgggcagtg attcaggcac
1081 catgggaagt gattcagatg aagagaatgt ggcagcaaga gcatccccgg agccagaact
1141 ccagctcagg ccttaccaaa tggaagttgc ccagccagcc ttggaaggga agaatatcat
1201 catctgcctc cctacaggga gtggaaaaac cagagtggct gtttacattg ccaaggatca
1261 cttagacaag aagaaaaaag catctgagcc tggaaaagtt atagttcttg tcaataaggt
1321 actgctagtt gaacagctct tccgcaagga gttccaacca tttttgaaga aatggtatcg
1381 tgttattgga ttaagtggtg atacccaact gaaaatatca tttccagaag ttgtcaagtc
1441 ctgtgatatt attatcagta cagctcaaat ccttgaaaac tccctcttaa acttggaaaa
1501 tggagaagat gctggtgttc aattgtcaga cttttccctc attatcattg atgaatgtca
1561 tcacaccaac aaagaagcag tgtataataa catcatgagg cattatttga tgcagaagtt
1621 gaaaaacaat agactcaaga aagaaaacaa accagtgatt ccccttcctc agatactggg
1681 actaacagct tcacctggtg ttggaggggc cacgaagcaa gccaaagctg aagaacacat
1741 tttaaaacta tgtgccaatc ttgatgcatt tactattaaa actgttaaag aaaaccttga
1801 tcaactgaaa aaccaaatac aggagccatg caagaagttt gccattgcag atgcaaccag
1861 agaagatcca tttaaagaga aacttctaga aataatgaca aggattcaaa cttattgtca
1921 aatgagtcca atgtcagatt ttggaactca accctatgaa caatgggcca ttcaaatgga
1981 aaaaaaagct gcaaaagaag gaaatcgcaa agaacgtgtt tgtgcagaac atttgaggaa
2041 gtacaatgag gccctacaaa ttaatgacac aattcgaatg atagatgcgt atactcatct
2101 tgaaactttc tataatgaag agaaagataa gaagtttgca gtcatagaag atgatagtga
2161 tgagggtggt gatgatgagt attgtgatgg tgatgaagat gaggatgatt taaagaaacc
2221 tttgaaactg gatgaaacag atagatttct catgacttta ttttttgaaa acaataaaat
2281 gttgaaaagg ctggctgaaa acccagaata tgaaaatgaa aagctgacca aattaagaaa
2341 taccataatg gagcaatata ctaggactga ggaatcagca cgaggaataa tctttacaaa
2401 aacacgacag agtgcatatg cgctttccca gtggattact gaaaatgaaa aatttgctga
2461 agtaggagtc aaagcccacc atctgattgg agctggacac agcagtgagt tcaaacccat
2521 gacacaaaaa aaaaaaaaaa
//