LOCUS BC075063 1803 bp mRNA linear HUM 08-MAR-2005
DEFINITION Homo sapiens interleukin 1 receptor, type I, mRNA (cDNA clone
MGC:104131 IMAGE:30915586), complete cds.
ACCESSION BC075063
VERSION BC075063.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1803)
AUTHORS Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1803)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (25-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 4, 2004 this sequence version replaced BC075063.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Genome Sequence Centre, British Columbia Cancer
Center
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRBU Plate: 5 Row: C Column: 11.
FEATURES Location/Qualifiers
source 1..1803
/db_xref="H-InvDB:HIT000265570"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:104131 IMAGE:30915586"
/tissue_type="Brain, PCR rescued clones"
/clone_lib="NIH_MGC_272"
/lab_host="DH10B"
/note="Vector: pCR4 Topo TA with reversed insert"
gene 1..1803
/gene="IL1R1"
/gene_synonym="CD121A"
/gene_synonym="D2S1473"
/gene_synonym="IL-1R-alpha"
/gene_synonym="IL1R"
/gene_synonym="IL1RA"
/gene_synonym="P80"
/db_xref="GeneID:3554"
/db_xref="MIM:147810"
CDS 45..1754
/gene="IL1R1"
/gene_synonym="CD121A"
/gene_synonym="D2S1473"
/gene_synonym="IL-1R-alpha"
/gene_synonym="IL1R"
/gene_synonym="IL1RA"
/gene_synonym="P80"
/codon_start=1
/product="interleukin 1 receptor, type I, precursor"
/protein_id="AAH75063.1"
/db_xref="GeneID:3554"
/db_xref="MIM:147810"
/translation="MKVLLRLICFIALLISSLEADKCKEREEKIILVSSANEIDVRPC
PLNPNEHKGTITWYKDDSKTPVSTEQASRIHQHKEKLWFVPAKVEDSGHYYCVVRNSS
YCLRIKISAKFVENEPNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELPKLQW
YKDCKPLLLDNIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITL
EENKPTRPVIVSPANETMEVDLGSQIQLICNVTGQLSDIAYWKWNGSVIDEDDPVLGE
DYYSVENPANKRRSTLITVLNISEIESRFYKHPFTCFAKNTHGIDAAYIQLIYPVTNF
QKHMIGICVTLTVIIVCSVFIYKIFKIDIVLWYRDSCYDFLPIKASDGKTYDAYILYP
KTVGEGSTSDCDIFVFKVLPEVLEKQCGYKLFIYGRDDYVGEDIVEVINENVKKSRRL
IIILVRETSGFSWLGGSSEEQIAMYNALVQDGIKVVLLELEKIQDYEKMPESIKFIKQ
KHGAIRWSGDFTQGPQSAKTRFWKNVRYHMPVQRRSPSSKHQLLSPATKEKLQREAHV
PLG"
BASE COUNT 577 a 329 c 400 g 497 t
ORIGIN
1 agctggaccc cttggtaaaa gacaaggcct tctccaagaa gaatatgaaa gtgttactca
61 gacttatttg tttcatagct ctactgattt cttctctgga ggctgataaa tgcaaggaac
121 gtgaagaaaa aataatttta gtgtcatctg caaatgaaat tgatgttcgt ccctgtcctc
181 ttaacccaaa tgaacacaaa ggcactataa cttggtataa agatgacagc aagacacctg
241 tatctacaga acaagcctcc aggattcatc aacacaaaga gaaactttgg tttgttcctg
301 ctaaggtgga ggattcagga cattactatt gcgtggtaag aaattcatct tactgcctca
361 gaattaaaat aagtgcaaaa tttgtggaga atgagcctaa cttatgttat aatgcacaag
421 ccatatttaa gcagaaacta cccgttgcag gagacggagg acttgtgtgc ccttatatgg
481 agttttttaa aaatgaaaat aatgagttac ctaaattaca gtggtataag gattgcaaac
541 ctctacttct tgacaatata cactttagtg gagtcaaaga taggctcatc gtgatgaatg
601 tggctgaaaa gcatagaggg aactatactt gtcatgcatc ctacacatac ttgggcaagc
661 aatatcctat tacccgggta atagaattta ttactctaga ggaaaacaaa cccacaaggc
721 ctgtgattgt gagcccagct aatgagacaa tggaagtaga cttgggatcc cagatacaat
781 tgatctgtaa tgtcaccggc cagttgagtg acattgctta ctggaagtgg aatgggtcag
841 taattgatga agatgaccca gtgctagggg aagactatta cagtgtggaa aatcctgcaa
901 acaaaagaag gagtaccctc atcacagtgc ttaatatatc ggaaattgaa agtagatttt
961 ataaacatcc atttacctgt tttgccaaga atacacatgg tatagatgca gcatatatcc
1021 agttaatata tccagtcact aatttccaga agcacatgat tggtatatgt gtcacgttga
1081 cagtcataat tgtgtgttct gttttcatct ataaaatctt caagattgac attgtgcttt
1141 ggtacaggga ttcctgctat gattttctcc caataaaagc ttcagatgga aagacctatg
1201 acgcatatat actgtatcca aagactgttg gggaagggtc tacctctgac tgtgatattt
1261 ttgtgtttaa agtcttgcct gaggtcttgg aaaaacagtg tggatataag ctgttcattt
1321 atggaaggga tgactacgtt ggggaagaca ttgttgaggt cattaatgaa aacgtaaaga
1381 aaagcagaag actgattatc attttagtca gagaaacatc aggcttcagc tggctgggtg
1441 gttcatctga agagcaaata gccatgtata atgctcttgt tcaggatgga attaaagttg
1501 tcctgcttga gctggagaaa atccaagact atgagaaaat gccagaatcg attaaattca
1561 ttaagcagaa acatggggct atccgctggt caggggactt tacacaggga ccacagtctg
1621 caaagacaag gttctggaag aatgtcaggt accacatgcc agtccagcga cggtcacctt
1681 catctaaaca ccagttactg tcaccagcca ctaaggagaa actgcaaaga gaggctcacg
1741 tgcctctcgg gtagcatgga gaagttgcca agagttcttt aggtgcctcc tgtcttatgg
1801 cgt
//