LOCUS BC075022 1713 bp mRNA linear HUM 08-MAR-2005
DEFINITION Homo sapiens potassium channel, subfamily K, member 10, transcript
variant 3, mRNA (cDNA clone MGC:104002 IMAGE:30915410), complete
cds.
ACCESSION BC075022
VERSION BC075022.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1713)
AUTHORS Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1713)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (25-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 4, 2004 this sequence version replaced BC075022.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Genome Sequence Centre, British Columbia Cancer
Center
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRBU Plate: 3 Row: E Column: 3.
FEATURES Location/Qualifiers
source 1..1713
/db_xref="H-InvDB:HIT000265529"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:104002 IMAGE:30915410"
/tissue_type="Pooled tissue, PCR rescued clones"
/clone_lib="NIH_MGC_271"
/note="Vector: pCR4 Topo TA with reversed insert"
gene 1..1713
/gene="KCNK10"
/gene_synonym="TREK-2"
/gene_synonym="TREK2"
/db_xref="GeneID:54207"
/db_xref="MIM:605873"
CDS 39..1670
/gene="KCNK10"
/gene_synonym="TREK-2"
/gene_synonym="TREK2"
/codon_start=1
/product="potassium channel, subfamily K, member 10,
isoform 3"
/protein_id="AAH75022.1"
/db_xref="GeneID:54207"
/db_xref="MIM:605873"
/translation="MEDGFKGDRTEGCRSDSVAVPAAAPVCQPKSATNGQPPAPAPTP
TPRLSISSRATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPF
ESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLG
SAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKS
IARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVV
VTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKT
KEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAH
SLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQGASEDNIIN
KFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEKMCNSDNSSTAM
LTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN"
BASE COUNT 416 a 432 c 499 g 366 t
ORIGIN
1 cacctgagag agtgacacac catgtacatg gctggtatat ggaggatgga tttaaggggg
61 acaggactga aggctgtcgc agtgattcag tggccgttcc cgcagcagca ccggtgtgcc
121 agcccaagag cgccactaac gggcaacccc cggctccggc tccgactcca actccgcgcc
181 tgtccatttc ctcccgagcc acagtggtag ccaggatgga aggcacctcc caagggggct
241 tgcagaccgt catgaagtgg aagacggtgg ttgccatctt tgtggttgtg gtggtctacc
301 ttgtcactgg cggtcttgtc ttccgggcat tggagcagcc ctttgagagc agccagaaga
361 ataccatcgc cttggagaag gcggaattcc tgcgggatca tgtctgtgtg agcccccagg
421 agctggagac gttgatccag catgctcttg atgctgacaa tgcgggagtc agtccaatag
481 gaaactcttc caacaacagc agccactggg acctcggcag tgcctttttc tttgctggaa
541 ctgtcattac gaccataggg tatgggaata ttgctccgag cactgaagga ggcaaaatct
601 tttgtatttt atatgccatc tttggaattc cactctttgg tttcttattg gctggaattg
661 gagaccaact tggaaccatc tttgggaaaa gcattgcaag agtggagaag gtctttcgaa
721 aaaagcaagt gagtcagacc aagatccggg tcatctcaac catcctgttc atcttggccg
781 gctgcattgt gtttgtgacg atccctgctg tcatctttaa gtacatcgag ggctggacgg
841 ccttggagtc catttacttt gtggtggtca ctctgaccac ggtgggcttt ggtgattttg
901 tggcaggggg aaacgctggc atcaattatc gggagtggta taagccccta gtgtggtttt
961 ggatccttgt tggccttgcc tactttgcag ctgtcctcag tatgatcgga gattggctac
1021 gggttctgtc caaaaagaca aaagaagagg tgggtgaaat caaggcccat gcggcagagt
1081 ggaaggccaa tgtcacggct gagttccggg agacacggcg aaggctcagc gtggagatcc
1141 acgataagct gcagcgggcg gccaccatcc gcagcatgga gcgccggcgg ctgggcctgg
1201 accagcgggc ccactcactg gacatgctgt cccccgagaa gcgctctgtc tttgctgccc
1261 tggacaccgg ccgcttcaag gcctcatccc aggagagcat caacaaccgg cccaacaacc
1321 tgcgcctgaa ggggccggag cagctgaaca agcatgggca gggtgcgtcc gaggacaaca
1381 tcatcaacaa gttcgggtcc acctccagac tcaccaagag gaaaaacaag gacctcaaaa
1441 agaccttgcc cgaggacgtt cagaaaatct acaagacctt ccggaattac tccctggacg
1501 aggagaagaa agaggaggag acggaaaaga tgtgtaactc agacaactcc agcacagcca
1561 tgctgacgga ctgtatccag cagcacgctg agttggagaa cggaatgata cccacggaca
1621 ccaaagaccg ggagccggag aacaactcat tacttgaaga cagaaactaa atgtgaagga
1681 cattggtctt ggactgagcg ttgtgtgtgt gtg
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