LOCUS BC075021 1716 bp mRNA linear HUM 08-MAR-2005
DEFINITION Homo sapiens potassium channel, subfamily K, member 10, transcript
variant 3, mRNA (cDNA clone MGC:104160 IMAGE:30915621), complete
cds.
ACCESSION BC075021
VERSION BC075021.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1716)
AUTHORS Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1716)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (25-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 4, 2004 this sequence version replaced BC075021.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Genome Sequence Centre, British Columbia Cancer
Center
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRBU Plate: 5 Row: F Column: 10.
FEATURES Location/Qualifiers
source 1..1716
/db_xref="H-InvDB:HIT000265528"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:104160 IMAGE:30915621"
/tissue_type="Pooled tissue, PCR rescued clones"
/clone_lib="NIH_MGC_271"
/note="Vector: pCR4 Topo TA with reversed insert"
gene 1..1716
/gene="KCNK10"
/gene_synonym="TREK-2"
/gene_synonym="TREK2"
/db_xref="GeneID:54207"
/db_xref="MIM:605873"
CDS 42..1673
/gene="KCNK10"
/gene_synonym="TREK-2"
/gene_synonym="TREK2"
/codon_start=1
/product="potassium channel, subfamily K, member 10,
isoform 3"
/protein_id="AAH75021.1"
/db_xref="GeneID:54207"
/db_xref="MIM:605873"
/translation="MEDGFKGDRTEGCRSDSVAVPAAAPVCQPKSATNGQPPAPAPTP
TPRLSISSRATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPF
ESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLG
SAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKS
IARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVV
VTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKT
KEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAH
SLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQGASEDNIIN
KFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEKMCNSDNSSTAM
LTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN"
BASE COUNT 417 a 432 c 500 g 367 t
ORIGIN
1 tgacacctga gagagtgaca caccatgtac atggctggta tatggaggat ggatttaagg
61 gggacaggac tgaaggctgt cgcagtgatt cagtggccgt tcccgcagca gcaccggtgt
121 gccagcccaa gagcgccact aacgggcaac ccccggctcc ggctccgact ccaactccgc
181 gcctgtccat ttcctcccga gccacagtgg tagccaggat ggaaggcacc tcccaagggg
241 gcttgcagac cgtcatgaag tggaagacgg tggttgccat ctttgtggtt gtggtggtct
301 accttgtcac tggcggtctt gtcttccggg cattggagca gccctttgag agcagccaga
361 agaataccat cgccttggag aaggcggaat tcctgcggga tcatgtctgt gtgagccccc
421 aggagctgga gacgttgatc cagcatgctc ttgatgctga caatgcggga gtcagtccaa
481 taggaaactc ttccaacaac agcagccact gggacctcgg cagtgccttt ttctttgctg
541 gaactgtcat tacgaccata gggtatggga atattgctcc gagcactgaa ggaggcaaaa
601 tcttttgtat tttatatgcc atctttggaa ttccactctt tggtttctta ttggctggaa
661 ttggagacca acttggaacc atctttggga aaagcattgc aagagtggag aaggtctttc
721 gaaaaaagca agtgagtcag accaagatcc gggtcatctc aaccatcctg ttcatcttgg
781 ccggctgcat tgtgtttgtg acgatccctg ctgtcatctt taagtacatc gagggctgga
841 cggccttgga gtccatttac tttgtggtgg tcactctgac cacggtgggc tttggtgatt
901 ttgtggcagg gggaaacgct ggcatcaatt atcgggagtg gtataagccc ctagtgtggt
961 tttggatcct tgttggcctt gcctactttg cagctgtcct cagtatgatc ggagattggc
1021 tacgggttct gtccaaaaag acaaaagaag aggtgggtga aatcaaggcc catgcggcag
1081 agtggaaggc caatgtcacg gctgagttcc gggagacacg gcgaaggctc agcgtggaga
1141 tccacgataa gctgcagcgg gcggccacca tccgcagcat ggagcgccgg cggctgggcc
1201 tggaccagcg ggcccactca ctggacatgc tgtcccccga gaagcgctct gtctttgctg
1261 ccctggacac cggccgcttc aaggcctcat cccaggagag catcaacaac cggcccaaca
1321 acctgcgcct gaaggggccg gagcagctga acaagcatgg gcagggtgcg tccgaggaca
1381 acatcatcaa caagttcggg tccacctcca gactcaccaa gaggaaaaac aaggacctca
1441 aaaagacctt gcccgaggac gttcagaaaa tctacaagac cttccggaat tactccctgg
1501 acgaggagaa gaaagaggag gagacggaaa agatgtgtaa ctcagacaac tccagcacag
1561 ccatgctgac ggactgtatc cagcagcacg ctgagttgga gaacggaatg atacccacgg
1621 acaccaaaga ccgggagccg gagaacaact cattacttga agacagaaac taaatgtgaa
1681 ggacattggt cttggactga gcgttgtgtg tgtgtg
//