LOCUS BC073996 4261 bp mRNA linear HUM 03-JAN-2005
DEFINITION Homo sapiens discs, large homolog 5 (Drosophila), mRNA (cDNA clone
IMAGE:6178261), partial cds.
ACCESSION BC073996
VERSION BC073996.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4261)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4261)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (23-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. James R. Lupski
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 174 Row: l Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 28466996.
FEATURES Location/Qualifiers
source 1..4261
/db_xref="H-InvDB:HIT000265216"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6178261"
/tissue_type="Peripheral Nervous System, dorsal root
ganglion"
/clone_lib="Lupski_dorsal_root_ganglion"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..4261
/gene="DLG5"
/gene_synonym="KIAA0583"
/gene_synonym="PDLG"
/db_xref="GeneID:9231"
/db_xref="MIM:604090"
CDS <1..2540
/gene="DLG5"
/gene_synonym="KIAA0583"
/gene_synonym="PDLG"
/codon_start=3
/product="DLG5 protein"
/protein_id="AAH73996.1"
/db_xref="GeneID:9231"
/db_xref="MIM:604090"
/translation="SSYYPEGDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRPKSAPS
FRPKLAPVVIPAQFLEEQKCVPASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVG
TVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLD
LSHRTCSDYSEMRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTPRYPRSVVGSERG
SVSHSECSTPPQSPLNIDTLSSCSQSQTSASTLPRIAVNPASLGERRKDRPYVEEPRH
VKVQKGSEPLGISIVSGEKGGIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQ
QARLIIGQQCDTITILAQYNPHVHQLSSHSRSSSHLDPAGTHSTLQGSGTTTPEHPSV
IDPLMEQDEGPSTPQAKQSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGGNLHGV
FVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQYRP
EEFTKAKGLPGDSFYIRALYDRLADVEQELSFKKDDILYVDDTLPQGTFGSWMAWQLD
ENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRS
GSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEML
VNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR
HCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEA
AQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL"
BASE COUNT 1027 a 1130 c 1124 g 980 t
ORIGIN
1 cttccagcta ctaccctgaa ggagatgggg actcctccca cctgccggcc aagaaatcct
61 gtgatgagga cctcacctcc cagaaggtgg atgagctggg gcagaagcgt cgccggccaa
121 aatctgctcc cagttttcgg ccgaagcttg ctccagtagt gattcctgct cagttcctgg
181 aggaacagaa gtgtgtcccg gccagtggag aactctcccc ggagctccag gagtgggcac
241 cttactcgcc tgggcattcc agccggcaca gcaacccccc gctataccct agcaggccgt
301 ctgtgggcac tgttccccgg agtttgaccc ccagcaccac tgtgagctcc atcctgcgga
361 accccatcta cactgtgcgc agtcacaggg tcggcccctg cagctctcca cctgcggccc
421 gagatgctgg cccccagggt ttgcatccca gtgtccagca ccagggacgc ctgagcctgg
481 acctgagcca caggacctgc agcgactact ccgagatgag agccacccat gggtccaact
541 cactgccctc cagcgcccgc ctgggttctt cgagtaactt gcagttcaag gcggaacgca
601 ttaaaatccc atcaacacca agatatccgc ggagtgtcgt gggctccgag agaggttcag
661 tgtcacattc tgaatgcagc actcctccac agtcacccct gaacatcgac accctgtcct
721 cttgtagcca gtcccagacc tcagcctcca cattgcccag aatcgctgtc aaccccgcgt
781 ccctcgggga gcggagaaag gacaggcctt atgtggagga gccacgccac gtgaaggtgc
841 agaagggctc agagccgctg ggcatctcca tcgtgagtgg agagaagggc ggcatctacg
901 tctccaaggt gaccgtgggg agcatcgctc accaggctgg cctcgagtat ggggatcagt
961 tactggagtt caacggcata aacctgcgga gcgccacgga gcagcaggcg cggctcatca
1021 tcgggcagca gtgtgatacc atcaccatcc tggcccagta caacccccac gtgcaccagc
1081 tcagcagcca ctcccggtcc agctcacacc tggaccctgc cggtacccac tccactctcc
1141 agggcagtgg caccaccacc ccggagcatc catctgtcat cgacccactg atggagcagg
1201 acgaggggcc tagcaccccc caagccaagc agagcagctc caggattgcg ggagatgcca
1261 acaagaagac cctggagcca cgcgttgtct tcatcaaaaa gtcccagctg gagcttgggg
1321 tgcacttgtg tggtgggaac ctgcatgggg tgtttgtggc cgaggtggag gatgacagtc
1381 ctgccaaggg tcctgacggc ctcgtgccag gggacctcat cctggagtat ggcagcctgg
1441 acgtgcggaa caagacagtg gaggaagtct atgtggagat gctgaagccc agggatggcg
1501 tccgcctgaa ggtgcagtac cgccctgagg agttcacgaa ggccaagggc ctgcctggtg
1561 acagcttcta catcagggcc ctgtacgacc ggctggcaga tgtggagcaa gagttgagct
1621 ttaagaagga cgacatcctc tacgtggatg acaccttacc ccagggcacg ttcgggtcct
1681 ggatggcttg gcagctggac gagaatgccc agaagatcca gcgcgggcag attcccagca
1741 aatatgtgat ggaccaagaa ttctccagga ggctcagcat gtctgaagtc aaagatgaca
1801 atagcgccac aaagacgctg tcagcggctg cacgccggtc cttttttcgg aggaaacaca
1861 agcacaaacg cagcgggtcc aaggacggga aagacctgct cgccttggat gccttttcca
1921 gtgactccat tccactcttt gaagattcgg tgagcctggc ctatcagcgg gtccagaagg
1981 tggactgcac cgctctgagg cctgtcctga ttctggggcc tttgctggac gtggtgaagg
2041 agatgctggt gaatgaggct cctggcaagt tctgcagatg tccccttgag gtgatgaagg
2101 cctcccagca ggccattgag cggggtgtca aagattgcct gtttgtcgac tataagcgga
2161 gaagcggcca tttcgatgtg accactgtgg cgtcaataaa ggagatcaca gaaaagaacc
2221 gacactgcct cctggacatt gctccgcacg ctattgagcg gctccaccac atgcacatct
2281 accccattgt catcttcatc cactacaaga gcgccaagca catcaaggag cagagagacc
2341 ccatctacct gagggacaag gtgactcaga ggcattccaa agagcagttt gaggcggcgc
2401 agaagcttga gcaggagtac agcaggtact tcacaggggt catccaggga ggagccctgt
2461 caagcatttg cactcagatc ttggcaatgg tcaatcaaga acaaaataaa gtcctgtgga
2521 ttccagcctg cccgctctag gagaatgctg tgctgtggat gactgcagct ggccgcctga
2581 ggggacgcca gactcagctc ttttctagcg actgaaagta gaagtctgtc cgtctatgaa
2641 catgcagggg aaggatccgg aaccaggacc cagaagcacc tcctttgtag acagagggcc
2701 acggctgcgt gcgatccagg cccaggccca cacactctgc ccgtgtcaca cgtgtgcttt
2761 aacacaaaac agataacact aaagacgggt tcagcaccca cctttcttta gccagctgat
2821 cagagatgct gcaaagagaa cctttcggat cactcgttta caagcctttt ctaagtattt
2881 ggtggtttat gtttacttga acggctccat gttgccggtg cccagcccct gtcccctctg
2941 tcaaccccct gtcgctttgg tgttggtttc gttcccgtct tcagcaaaac gaccttggaa
3001 cctcaatggg ggctgctttg ctttgggagg ttcttgttgg tgggaccaga gctttgacaa
3061 acctcctgct ccttggtggc acctctcctg gaaggacgtc acaactccag gtgctcagac
3121 tgcctgtggc agcagaacca gtgcctttgg cattttcctc ccacaatggg gaaggtgact
3181 ttggcattct tacaaactcg tctctcggcc tttctctcct gccttccaca gcctctcgtt
3241 tctcctccat ctgtgcttat tacttgagga ctgtgtctgc tccgtgagag ctgcgtgggc
3301 agggctgcag tggggtccag gtggtgttca gctgtgctga tgcctgccat tgggtcctcc
3361 ttaggctctg taagtcgtga cagccttcat cagtgcaatg tttgcagggt aattcttaaa
3421 ctttttagag ggtggcaggt acatcagttc tttttgatat gaaaacattc atgtttcaga
3481 cattgaattg agagctttta ggggaagcat aatggttatt gtcactatca acagtctaaa
3541 aagaaaaact gaggtctttt taatcttgat tacagcactc acggcatgca ccctactcag
3601 tgtgggtgtc ttcgtttggg ggcttttttt tttttttttg cacttctgag gctagatatg
3661 tctggctgaa gatttgatgt ggttcctcct taagctatgc gtcctgttaa taataggtac
3721 tgtactgggc tctgtgtaag tgtcgttggg gtaggaccta tattttaata ctgttcctaa
3781 catttcattt tactagcgag aaatctttga tttcatttta ttctttgtaa ttctagacac
3841 tagattgtag tttagccata actgatgttt tttaaaaagg gatatatttt cttgcacagt
3901 tgttcaaaaa aagagacaag tttcagtcct caatgctgtc ctttgtttta caggtacaag
3961 ttttctagct cagacaaact atgaaaaact gtagactatt ctcaaggtat taactcgcag
4021 accctctggg ggtaggggct gttttctaag ttacaggcag agtgggactg agatggtaca
4081 gtgtgcacag acaggtactg agctgacaga ctgggatttt ctgtactaaa atgttacttt
4141 gtatcaaaag ttaaacaggc tttagtacaa caaataaagg tcaatttctg taaaaaaaaa
4201 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4261 a
//