LOCUS BC073163 2184 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens guanylate binding protein 2, interferon-inducible,
mRNA (cDNA clone MGC:87973 IMAGE:6151056), complete cds.
ACCESSION BC073163
VERSION BC073163.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2184)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2184)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 174 Row: j Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38327557.
FEATURES Location/Qualifiers
source 1..2184
/db_xref="H-InvDB:HIT000264958"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87973 IMAGE:6151056"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2184
/gene="GBP2"
/db_xref="GeneID:2634"
/db_xref="HGNC:HGNC:4183"
/db_xref="MIM:600412"
CDS 252..2027
/gene="GBP2"
/codon_start=1
/product="guanylate binding protein 2,
interferon-inducible"
/protein_id="AAH73163.1"
/db_xref="GeneID:2634"
/db_xref="HGNC:HGNC:4183"
/db_xref="MIM:600412"
/translation="MAPEINLPGPMSLIDNTKGQLVVNPEALKILSAITQPVVVVAIV
GLYRTGKSYLMNKLAGKKNGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLG
DIEKGDNENDSWIFALAILLSSTFVYNSMGTINQQAMDQLHYVTELTDRIKANSSPGN
NSVDDSADFVSFFPAFVWTLRDFTLELEVDGEPITADDYLELSLKLRKGTDKKSKSFN
DPRLCIRKFFPKRKCFVFDWPAPKKYLAHLEQLKEEELNPDFIEQVAEFCSYILSHSN
VKTLSGGIPVNGPRLESLVLTYVNAISSGDLPCRENAVLALAQIENSAAVEKAIAHYE
QQMGQKVQLPTETLQELLDLHRDSEREAIEVFMKNSFKDVDQMFQRKLGAQLEARRDD
FCKQNSKASSDCCMALLQDIFGPLEEDVKQGTFSKPGGYRLFTQKLQELKNKYYQVPR
KGIQAKEVLKKYLESKEDVADALLQTDQSLSEKEKAIEVERIKAESAEAAKKMLEEIQ
KKNEEMMEQKEKSYQEHVKQLTEKMERDRAQLMAEQEKTLALKLQEQERLLKEGFENE
SKRLQKDIWDIQMRSKSLEPICNIL"
BASE COUNT 711 a 468 c 548 g 457 t
ORIGIN
1 gcagaggtta cctctttttc ttgtctctcg tcaggtctct gacattgaca gagcctggac
61 gttggaggaa gccccaggac gttggagggg taaagtaaaa gtccacagtt accgtgagag
121 aaaaaagagg gagaaagcag tgcagccaaa ctcggaagaa aagagaggag gaaaaggact
181 cgactttcac attggaacaa ccttctttcc agtgctaaag gatctctgat ctggggaaca
241 acaccctgga catggctcca gagatcaact tgccgggccc aatgagcctc attgataaca
301 ctaaagggca gctggtggtg aatccagaag ctctgaagat cctatctgca attacgcagc
361 ctgtggtggt ggtggcgatt gtgggcctct atcgcacagg caaatcctac ctgatgaaca
421 agctggctgg gaagaaaaac ggcttctctc taggctccac agtgaagtct cacaccaagg
481 gaatctggat gtggtgtgtg cctcatccca agaagccaga acacacccta gttctgctcg
541 acactgaggg cctgggagat atagagaagg gtgacaatga gaatgactcc tggatctttg
601 ccttggccat cctcctgagc agcaccttcg tgtacaatag catgggaacc atcaaccagc
661 aggccatgga ccaacttcac tatgtgacag agctgacaga tcgaatcaag gcaaactcct
721 cacctggtaa caattctgta gacgactcag ctgactttgt gagctttttt ccagcatttg
781 tgtggactct cagagatttc accctggaac tggaagtaga tggagaaccc atcactgctg
841 atgactactt ggagctttcg ctaaagctaa gaaaaggtac tgataagaaa agtaaaagct
901 ttaatgatcc tcggttgtgc atccgaaagt tcttccccaa gaggaagtgc ttcgtcttcg
961 attggcccgc tcctaagaag taccttgctc acctagagca gctaaaggag gaagagctga
1021 accctgattt catagaacaa gttgcagaat tttgttccta catcctcagc cattccaatg
1081 tcaagactct ttcaggtggc attccagtca atgggcctcg tctagagagc ctggtgctga
1141 cctacgtcaa tgccatcagc agtggggatc taccctgcag ggagaacgca gtcctggcct
1201 tggcccagat agagaactca gccgcagtgg aaaaggctat tgcccactat gaacagcaga
1261 tgggccagaa ggtgcagctg cccacggaaa ccctccagga gctgctggac ctgcacaggg
1321 acagtgagag agaggccatt gaagtcttca tgaagaactc tttcaaggat gtggaccaaa
1381 tgttccagag gaaattaggg gcccagttgg aagcaaggcg agatgacttt tgtaagcaga
1441 attccaaagc atcatcagat tgttgcatgg ctttacttca ggatatattt ggccctttag
1501 aagaagatgt caagcaggga acattttcta aaccaggagg ttaccgtctc tttactcaga
1561 agctgcagga gctgaagaat aagtactacc aggtgccaag gaaggggata caggccaaag
1621 aggtgctgaa aaaatatttg gagtccaagg aggatgtggc tgatgcactt ctacagactg
1681 atcagtcact ctcagaaaag gaaaaagcga ttgaagtgga acgtataaag gctgaatctg
1741 cagaagctgc aaagaaaatg ttggaggaaa tacaaaagaa gaatgaggag atgatggaac
1801 agaaagagaa gagttatcag gaacatgtga aacaattgac tgagaagatg gagagggaca
1861 gggcccagtt aatggcagag caagagaaga ccctcgctct taaacttcag gaacaggaac
1921 gccttctcaa ggagggattc gagaatgaga gcaagagact tcaaaaagac atatgggata
1981 tccagatgag aagcaaatca ttggagccaa tatgtaacat actctaaaag tccaaggagc
2041 aaaatttgcc tgtccagctc cctctcccca agaaacaaca tgaatgagca acttcagagt
2101 gtcaaacaac tgccattaaa cttaactcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2161 aaaaaaaaaa aaaaaaaaaa aaaa
//