LOCUS BC072448 3526 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens F-box and leucine-rich repeat protein 3, mRNA (cDNA
clone MGC:90244 IMAGE:6166244), complete cds.
ACCESSION BC072448
VERSION BC072448.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3526)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3526)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 174 Row: k Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16306583.
FEATURES Location/Qualifiers
source 1..3526
/db_xref="H-InvDB:HIT000264892"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:90244 IMAGE:6166244"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3526
/gene="FBXL3"
/gene_synonym="FBL3"
/gene_synonym="FBL3A"
/db_xref="GeneID:26224"
/db_xref="HGNC:HGNC:13599"
/db_xref="MIM:605653"
CDS 326..1612
/gene="FBXL3"
/gene_synonym="FBL3"
/gene_synonym="FBL3A"
/codon_start=1
/product="F-box and leucine-rich repeat protein 3"
/protein_id="AAH72448.1"
/db_xref="GeneID:26224"
/db_xref="HGNC:HGNC:13599"
/db_xref="MIM:605653"
/translation="MKRGGRDSDRNSSEEGTAEKSKKLRTTNEHSQTCDWGNLLQDII
LQVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQI
IKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARPSFMDLPKSHF
ISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILC
VADQCHGLRELALNYHLLSDELLLALSSEKHVRLEHLRIDVVSENPGQTHFHTIQKSS
WDAFIRHSPKVNLVMYFFLYEEEFDPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRL
VELVVCANGLRPLDEELIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSI
MEEVLIPDQKYSLEQIHWEVSKHLGRVWFPDMMPTW"
BASE COUNT 1111 a 598 c 727 g 1090 t
ORIGIN
1 gtttgtggcc caggtgcagg aagcttacgc ggtggcagcc gctcgctgag gtagtctctc
61 gcggcgccgg ggatccctga acacagacag cgcgggactg agaaggaaag cttctttctg
121 ggcagccaga gccgcaaagg tggagccgcg ttggcgccct ccgcgggacc agcgcctcgg
181 atgcgggcgg agcgcggggg gccgcggctg cgggagcgcg aagcgggggg ccaggggcgc
241 ctcatgtgag agccgcggga cctgcagccg ccgccgtccc cggagcacgg ggtggtgtgt
301 gggggaagcc gcccccggca gcaggatgaa acgaggagga agagatagtg accgtaattc
361 atcagaagaa ggaactgcag agaaatccaa gaaactgagg actacaaatg agcattctca
421 gacttgtgat tggggtaatc tccttcagga cattattctc caagtattta aatatttgcc
481 tcttcttgac cgggctcatg cttcacaagt ttgccgcaac tggaaccagg tatttcacat
541 gcctgacttg tggagatgtt ttgaatttga actgaatcag ccagctacat cttatttgaa
601 agctacccat ccagagctga tcaaacagat tattaaaaga cattcaaacc atctacaata
661 tgtcagcttc aaggtggaca gcagcaagga atcagctgaa gcagcttgtg atatactatc
721 gcaacttgtg aattgctctt taaaaacact tggacttatt tcaactgctc gaccaagctt
781 tatggattta ccaaagtctc actttatctc tgcactgaca gttgtgttcg taaactccaa
841 atccctgtct tcgcttaaga tagatgatac tccagtagat gatccatctc tcaaagtact
901 agtggccaac aatagtgata cactcaagct gttgaaaatg agcagctgtc ctcatgtctc
961 tccagcaggt atcctttgtg tggctgatca gtgtcacggc ttaagagaac tagccctgaa
1021 ctaccactta ttgagtgatg agttgttact tgcattgtct tctgaaaaac atgttcgatt
1081 agaacatttg cgcattgatg tagtcagtga gaatcctgga cagacacact tccatactat
1141 tcagaagagt agctgggatg ctttcatcag acattcaccc aaagtgaact tagtgatgta
1201 ttttttttta tatgaagaag aatttgaccc cttctttcgc tatgaaatac ctgccaccca
1261 tctgtacttt gggagatcag taagcaaaga tgtgcttggc cgtgtgggaa tgacatgccc
1321 tagactggtt gaactagtag tgtgtgcaaa tggattacgg ccacttgatg aagagttaat
1381 tcgcattgca gaacgttgca aaaatttgtc agctattgga ctaggggaat gtgaagtctc
1441 atgtagtgcc tttgttgagt ttgtgaagat gtgtggtggc cgcctatctc aattatccat
1501 tatggaagaa gtactaattc ctgaccaaaa gtatagtttg gagcagattc actgggaagt
1561 gtccaagcat cttggtaggg tgtggtttcc cgacatgatg cccacttggt aaaaactgca
1621 tgatgaatag caccttaatt tcaagcaaat gtattataat taaagtttta tttgctgtag
1681 ttctgatata attctactat tttgtggcac agaaatttga tatcttcagt cagtatatgt
1741 aaagattgtt tatcggaaga cccatgaatg agttttggtc agaaaattcc acttgtttcc
1801 ttagtgtaat agcagtcata tctccgaatt ttttttaatg tggttcggat gtgaaataac
1861 cagttatacg tattaaacag tttacagtct aaaggaaaca aaacctatat gttataatat
1921 ccaagaagta ctaataggtt ttctgaaatg ttatattctc tatgcattta aaaaaaaatg
1981 taaacttgac attttagggt cttcagttac acatacacct gttataaggt gtttaatata
2041 gctcaggaaa gtgagcattt tgtgagaaaa atgaatatat catatctaat ggaaaagatt
2101 ggatgaatgt tctcaaatgt tacaaagctg tttaaagaaa aaggtatata taagtaatca
2161 gaacacttag aagactgata gatgtcacac agtggtatta tagaaggata atacagagcc
2221 aagatcaaat taaaagacaa taaatggaac agaagggagg cagtgtttag ctttgtataa
2281 acttttaggt ttgctctgta atctgctaaa ccatatacat tcttttgtga tatgttatta
2341 tgtatgtggc acttgaggca ctgtatgtaa agtaaggaat gctttactag ttctccttgg
2401 ttttatcttt gtttaaacta gctttaaagt attaaacaat aattgaaatg aaaagcttac
2461 ctattttaaa aagccaaatt taaataaata tagaacttta aaatgtttat cagttgtttc
2521 catgaaagaa tattagtttc cagtaaattt tagtgatggc tcactcactt ttctattttg
2581 gaattacata gttatgtaag taaaattttt aaaaatcata aagggagcac cattgtacag
2641 tctagcataa acagcaaatt ttaaagagga catatttaag ttcataatca tatttttcag
2701 taaatattgc tcagtgaact ggaaaacttt aatagaaaaa tgtctgcagt tttgtgattg
2761 ttaatttggt taaaccgata ttttatatta tttaagttag gtaacatttt atattacttt
2821 catatgaata aaagtaatcc atgcattgta gagtctataa aatgttgagt ttttttagat
2881 gatataaact ttgattctgg gcactagtgc tagtagatat tactaccctc ctgagggaaa
2941 tcagaaatga tttaacccca gtggaataca ttaattctta aagcggctct tttcagtagt
3001 gtgactttta gaaagtgtct cagtagttaa ggaagctaac agtcttagat ctacttttaa
3061 aacggatggc cttcttaaga ataaagcaaa aggtgatttt ctacataatt tttgctttcc
3121 aaaagtgatg atatgctctc ctacagcaac atatgagaag aaaaaaggct tatctagatt
3181 cgaaaattaa cagcaattat agtaatatat cccctccttc taaatagtaa aaagctctga
3241 ttgtacaaga attacctgtg ctagtcaagt tgttgttttt ccttgaacaa ctttggaaaa
3301 atggatttga cagtacataa tcagttctac taaccaaagc ttgtatttgg aaatttactt
3361 tttgtacaaa ttgaattata taatgcttaa aatactttgt cactttataa gcaaaatgca
3421 tagtacttaa tttgtttata ctgtaaagta tatgttaaat gcttttatca ctttgagaat
3481 aaaaagttac taatgctgtt gtaaaaaaaa aaaaaaaaaa aaaaaa
//