LOCUS BC072015 1710 bp mRNA linear HUM 22-FEB-2007
DEFINITION Homo sapiens low density lipoprotein-related protein 1
(alpha-2-macroglobulin receptor), mRNA (cDNA clone IMAGE:6384902),
complete cds.
ACCESSION BC072015
VERSION BC072015.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1710)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1710)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 58 Row: m Column: 14
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1710
/db_xref="H-InvDB:HIT000264818"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6384902"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1710
/gene="LRP1"
/gene_synonym="APOER"
/gene_synonym="CD91"
/gene_synonym="LRP"
/gene_synonym="TGFBR5"
/db_xref="GeneID:4035"
/db_xref="HGNC:HGNC:6692"
/db_xref="MIM:107770"
CDS 473..1363
/gene="LRP1"
/gene_synonym="APOER"
/gene_synonym="CD91"
/gene_synonym="LRP"
/gene_synonym="TGFBR5"
/codon_start=1
/product="LRP1 protein"
/protein_id="AAH72015.1"
/db_xref="GeneID:4035"
/db_xref="HGNC:HGNC:6692"
/db_xref="MIM:107770"
/translation="MLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKG
WRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELCVPMSRLCNGVQDCMDGS
DEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTC
SQLCTNTDGSFICGCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQ
VSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMPGLKGFVDEHTINIS
LSLHRRSRKRAQENEVTQHG"
BASE COUNT 406 a 509 c 506 g 289 t
ORIGIN
1 ggggaacagc ggtgcgagct ccaggcccat gcactgagga ggcggaaaca aggggagccc
61 ccagagctcc atcaagcccc ctccaaaggc tcccctaccc ggtccacgcc ccccaccccc
121 cctccccgcc tcctcccaat tgtgcatttt tgcagccgga ggcggctccg agatggggct
181 gtgagcttcg cccggggagg gggaaagagc agcgaggagt gaagcggggg ggtggggtga
241 agggtttgga tttcggggca gggggcgcac ccccgtcagc aggccctccc caaggggctc
301 ggaactctac ctcttcaccc acgcccctgg tgcgctttgc cgaaggaaag aataagaaca
361 gagaaggagg agggggaaag gaggaaaagg gggacccccc aactgggggg ggtgaaggag
421 agaagtagca ggaccagagg ggaaggggct gctgcttgca tcagcccaca ccatgctgac
481 cccgccgttg ctcctgctgc tgcccctgct ctcagctctg gtcgcggcgg ctatcgacgc
541 ccctaagact tgcagcccca agcagtttgc ctgcagagat caaataacct gtatctcaaa
601 gggctggcgg tgcgacggtg agagggactg cccagacgga tctgacgagg cccctgagat
661 ttgtccacag agtaaggccc agcgatgcca gccaaacgag cataactgcc tgggtactga
721 gctgtgtgtt cccatgtccc gcctctgcaa tggggtccag gactgcatgg acggctcaga
781 tgaggggccc cactgccgag agctccaagg caactgctct cgcctgggct gccagcacca
841 ttgtgtcccc acactcgatg ggcccacctg ctactgcaac agcagctttc agcttcaggc
901 agatggcaag acctgcaaag attttgatga gtgctcagtg tacggcacct gcagccagct
961 atgcaccaac acagacggct ccttcatatg tggctgtgtt gaaggatacc tcctgcagcc
1021 ggataaccgc tcctgcaagg ccaagaacga gccagtagac cggccccctg tgctgttgat
1081 agccaactcc cagaacatct tggccacgta cctgagtggg gcccaggtgt ctaccatcac
1141 acctacgagc acgcggcaga ccacagccat ggacttcagc tatgccaacg agaccgtatg
1201 ctgggtgcat gttggggaca gtgctgctca gacgcagctc aagtgtgccc gcatgcctgg
1261 cctaaagggc ttcgtggatg agcacaccat caacatctcc ctcagtctgc accgcaggag
1321 caggaagaga gcccaggaga acgaggtgac acaacacggc taagctccag actggctggt
1381 ggaaggaaga gctgaagtcg ggacccagca ggaaacaagg agcatgaggc cacatcgttt
1441 agcagagctt ctgccaggct cgccaggagg tctccttccc accttcgaag tcctcagact
1501 ctccgccatc tctcccaggc ccaggcgaga tccctgagta ggattactag acagactgtc
1561 ctctcccact gtcttggagt gtcccaaggc cagagaggca ggatcctggc agtagaagag
1621 agggggaaaa tgatgtccca gctctagaac aacagactca gtcttcaata aatatttgtt
1681 caatggatca ataaaaaaaa aaaaaaaaaa
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