LOCUS BC071897 2558 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens myeloid cell leukemia sequence 1 (BCL2-related), mRNA
(cDNA clone MGC:88576 IMAGE:6586159), complete cds.
ACCESSION BC071897
VERSION BC071897.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2558)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2558)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 58 Row: o Column: 10.
FEATURES Location/Qualifiers
source 1..2558
/db_xref="H-InvDB:HIT000264708"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:88576 IMAGE:6586159"
/tissue_type="Breast, adenocarcinoma"
/clone_lib="NIH_MGC_107"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2558
/gene="MCL1"
/gene_synonym="EAT"
/gene_synonym="MCL1L"
/gene_synonym="MCL1S"
/gene_synonym="MGC1839"
/gene_synonym="TM"
/db_xref="GeneID:4170"
/db_xref="HGNC:HGNC:6943"
/db_xref="MIM:159552"
CDS 57..1109
/gene="MCL1"
/gene_synonym="EAT"
/gene_synonym="MCL1L"
/gene_synonym="MCL1S"
/gene_synonym="MGC1839"
/gene_synonym="TM"
/codon_start=1
/product="myeloid cell leukemia sequence 1 (BCL2-related)"
/protein_id="AAH71897.1"
/db_xref="GeneID:4170"
/db_xref="HGNC:HGNC:6943"
/db_xref="MIM:159552"
/translation="MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASA
RREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPT
RRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSL
PSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGD
GVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAK
HLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLA
FAGVAGVGAGLAYLIR"
BASE COUNT 692 a 537 c 656 g 673 t
ORIGIN
1 gtaaggagtc ggggtcttcc ccagttttct cagccaggcg gcggcggcga ctggcaatgt
61 ttggcctcaa aagaaacgcg gtaatcggac tcaacctcta ctgtgggggg gccggcttgg
121 gggccggcag cggcggcgcc acccgcccgg gagggcgact tttggctacg gagaaggagg
181 cctcggcccg gcgagagata gggggagggg aggccggcgc ggtgattggc ggaagcgccg
241 gcgcaagccc cccgtccacc ctcacgccag actcccggag ggtcgcgcgg ccgccgccca
301 ttggcgccga ggtccccgac gtcaccgcga cccccgcgag gctgcttttc ttcgcgccca
361 cccgccgcgc ggcgccgctt gaggagatgg aagccccggc cgctgacgcc atcatgtcgc
421 ccgaagagga gctggacggg tacgagccgg agcctctcgg gaagcggccg gctgtcctgc
481 cgctgctgga gttggtcggg gaatctggta ataacaccag tacggacggg tcactaccct
541 cgacgccgcc gccagcagag gaggaggagg acgagttgta ccggcagtcg ctggagatta
601 tctctcggta ccttcgggag caggccaccg gcgccaagga cacaaagcca atgggcaggt
661 ctggggccac cagcaggaag gcgctggaga ccttacgacg ggttggggat ggcgtgcagc
721 gcaaccacga gacggccttc caaggcatgc ttcggaaact ggacatcaaa aacgaagacg
781 atgtgaaatc gttgtctcga gtgatgatcc atgttttcag cgacggcgta acaaactggg
841 gcaggattgt gactctcatt tcttttggtg cctttgtggc taaacacttg aagaccataa
901 accaagaaag ctgcatcgaa ccattagcag aaagtatcac agacgttctc gtaaggacaa
961 aacgggactg gctagttaaa caaagaggct gggatgggtt tgtggagttc ttccatgtag
1021 aggacctaga aggtggcatc aggaatgtgc tgctggcttt tgcaggtgtt gctggagtag
1081 gagctggttt ggcatatcta ataagatagc cttactgtaa gtgcaatagt tgacttttaa
1141 ccaaccacca ccaccaccaa aaccagttta tgcagttgga ctccaagctg taacttccta
1201 gagttgcacc ctagcaacct agccagaaaa gcaagtggca agaggattat ggctaacaag
1261 aataaataca tgggaagagt gctccccatt gattgaagag tcactgtctg aaagaagcaa
1321 agttcagttt cagcaacaaa caaactttgt ttgggaagct atggaggagg acttttagat
1381 ttagtgaaga tggtagggtg gaaagactta atttccttgt tgagaacagg aaagtggcca
1441 gtagccaggc aagtcataga attgattacc cgccgaattc attaatttac tgtagtgtta
1501 agagaagcac taagaatgcc agtgacctgt gtaaaagtta caagtaatag aactatgact
1561 gtaagcctca gtactgtaca agggaagctt ttcctctctc taattagctt tcccagtata
1621 cttcttagaa agtccaagtg ttcaggactt ttatacctgt tatactttgg cttggtttcc
1681 atgattctta ctttattagc ctagtttatc accaataata cttgacggaa ggctcagtaa
1741 ttagttatga atatggatat cctcaattct taagacagct tgtaaatgta tttgtaaaaa
1801 ttgtatatat ttttacagaa agtctatttc tttgaaacga aggaagtatc gaatttacat
1861 tagttttttt catacccttt tgaactttgc aacttccgta attaggaacc tgtttcttac
1921 agcttttcta tgctaaactt tgttctgttc agttctagag tgtatacaga acgaattgat
1981 gtgtaactgt atgcagactg gttgtagtgg aacaaatctg ataactatgc aggtttaaat
2041 tttcttatct gattttggta agtattcctt agataggttt ttctttgaaa acctgggatt
2101 gagaggttga tgaatggaaa ttctttcact tcattatatg caagttttca ataattaggt
2161 ctaagtggag ttttaaggtt actgatgact tacaaataat gggctctgat tgggcaatac
2221 tcatttgagt tccttccatt tgacctaatt taactggtga aatttaaagt gaattcatgg
2281 gctcatcttt aaagctttta ctaaaagatt ttcagctgaa tggaactcat tagctgtgtg
2341 catataaaaa gatcacatca ggtggatgga gagacatttg atcccttgtt tgcttaataa
2401 attataaaat gatggcttgg aaaagcaggc tagtctaacc atggtgctat tattaggctt
2461 gcttgttaca cacacaggtc taagcctagt atgtcaataa agcaaatact tactgttttg
2521 tttctattaa tgattcccaa aaaaaaaaaa aaaaaaaa
//