LOCUS BC071874 2062 bp mRNA linear HUM 26-JUN-2004
DEFINITION Homo sapiens carboxylesterase 2 (intestine, liver), mRNA (cDNA
clone IMAGE:6284741), partial cds.
ACCESSION BC071874
VERSION BC071874.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2062)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2062)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CGAP (Stanford)
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 58 Row: k Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21536284.
FEATURES Location/Qualifiers
source 1..2062
/db_xref="H-InvDB:HIT000264687"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6284741"
/tissue_type="Liver, hepatocellular carcinoma"
/clone_lib="NIH_MGC_100"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene <1..2062
/gene="CES2"
/gene_synonym="CE-2"
/gene_synonym="iCE"
/db_xref="GeneID:8824"
/db_xref="MIM:605278"
CDS <1..1763
/gene="CES2"
/gene_synonym="CE-2"
/gene_synonym="iCE"
/codon_start=3
/product="CES2 protein"
/protein_id="AAH71874.1"
/db_xref="GeneID:8824"
/db_xref="MIM:605278"
/translation="LTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTETSEPTM
RLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFL
GIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSD
SMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVII
QYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTS
VSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGC
LRGKSKEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWL
IPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQF
QEMMADSMFVIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHVKFTEEEE
QLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWK
KALPQKIQELEEPEERHTEL"
BASE COUNT 451 a 587 c 592 g 432 t
ORIGIN
1 cgctgactcc ctgcccagtc caaactccaa ggctgggcaa ggcactgatc cactgctgga
61 cagacccggg gcagcctctg ggtgaacagc agcgtgtccg ccggcagcga accgagacca
121 gcgagccgac catgcggctg cacagacttc gtgcgcggct gagcgcggtg gcctgtgggc
181 ttctgctgct tcttgtccgg ggccagggcc aggactcagc cagtcccatc cggaccacac
241 acacggggca ggtgctgggg agtcttgtcc atgtgaaggg cgccaatgcc ggggtccaaa
301 ccttcctggg aattccattt gccaagccac ctctaggtcc gctgcgattt gcaccccctg
361 agccccctga atcttggagt ggtgtgaggg atggaaccac ccatccggcc atgtgtctac
421 aggacctcac cgcagtggag tcagagtttc ttagccagtt caacatgacc ttcccttccg
481 actccatgtc tgaggactgc ctgtacctca gcatctacac gccggcccat agccatgaag
541 gctctaacct gccggtgatg gtgtggatcc acggtggtgc gcttgttttt ggcatggctt
601 ccttgtatga tggttccatg ctggctgcct tggagaacgt ggtggtggtc atcatccagt
661 accgcctggg tgtcctgggc ttcttcagca ctggagacaa gcacgcaacc ggcaactggg
721 gctacctgga ccaagtggct gcactacgct gggtccagca gaatatcgcc cactttggag
781 gcaaccctga ccgtgtcacc atttttggcg agtctgcggg tggcacgagt gtgtcttcgc
841 ttgttgtgtc ccccatatcc caaggactct tccacggagc catcatggag agtggcgtgg
901 ccctcctgcc cggcctcatt gccagctcag ctgatgtcat ctccacggtg gtggccaacc
961 tgtctgcctg tgaccaagtt gactctgagg ccctggtggg ctgcctgcgg ggcaagagta
1021 aagaggagat tcttgcaatt aacaagcctt tcaagatgat ccccggagtg gtggatgggg
1081 tcttcctgcc caggcacccc caggagctgc tggcctctgc cgactttcag cctgtcccta
1141 gcattgttgg tgtcaacaac aatgaattcg gctggctcat ccccaaggtc atgaggatct
1201 atgataccca gaaggaaatg gacagagagg cctcccaggc tgctctgcag aaaatgttaa
1261 cgctgctgat gttgcctcct acatttggtg acctgctgag ggaggagtac attggggaca
1321 atggggatcc ccagaccctc caagcgcagt tccaggagat gatggcggac tccatgtttg
1381 tgatccctgc actccaagta gcacattttc agtgttcccg ggcccctgtg tacttctacg
1441 agttccagca tcagcccagc tggctcaaga acatcaggcc accgcacatg aaggcagacc
1501 atgttaaatt cactgaggaa gaggagcagc taagcaggaa gatgatgaag tactgggcca
1561 actttgcgag aaatgggaac cccaatggcg agggtctgcc acactggccg ctgttcgacc
1621 aggaggagca atacctgcag ctgaacctac agcctgcggt gggccgggct ctgaaggccc
1681 acaggctcca gttctggaag aaggcgctgc cccaaaagat ccaggagctc gaggagcctg
1741 aagagagaca cacagagctg tagctccctg tgccggggag gagggggtgg gttcgctgac
1801 aggcgagggt cagcctgctg tgcccacaca cacccactaa ggagaaagaa gttgattcct
1861 tcattcactt cgccattcat tcatacttcc gtccatccat tcagaaagca tttattaaga
1921 atttactcag gcatgatggc ccatacttgt aatcccagct attgggaagg atgagatggg
1981 aggatggctt gaggccagag gtttgagacc gaccagccag ggcaacacag tgagacccct
2041 tctcaaaaaa aaaaaaaaaa aa
//