LOCUS       BC071848                1466 bp    mRNA    linear   HUM 30-JUN-2004
DEFINITION  Homo sapiens reticulon 4, mRNA (cDNA clone IMAGE:4635625), complete
            cds.
ACCESSION   BC071848
VERSION     BC071848.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1466)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 1466)
  AUTHORS   Strausberg,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUN-2004) National Institutes of Health, Mammalian
            Gene Collection (MGC), Cancer Genomics Office, National Cancer
            Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
            USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: ATCC
            cDNA Library Preparation: Rubin Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:       http://www-shgc.stanford.edu
            Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 58 Row: d Column: 23
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 24431932
            This clone has the following problem: The cds is short compared to
            the longest cds in the locus.
FEATURES             Location/Qualifiers
     source          1..1466
                     /db_xref="H-InvDB:HIT000264661"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="IMAGE:4635625"
                     /tissue_type="Eye, retinoblastoma"
                     /clone_lib="NIH_MGC_16"
                     /lab_host="DH10B-R"
                     /note="Vector: pOTB7"
     gene            1..1466
                     /gene="RTN4"
                     /gene_synonym="ASY"
                     /gene_synonym="NI220/250"
                     /gene_synonym="NOGO"
                     /gene_synonym="NSP"
                     /gene_synonym="NSP-CL"
                     /gene_synonym="RTN-X"
                     /db_xref="GeneID:57142"
                     /db_xref="MIM:604475"
     CDS             77..1108
                     /gene="RTN4"
                     /gene_synonym="ASY"
                     /gene_synonym="NI220/250"
                     /gene_synonym="NOGO"
                     /gene_synonym="NSP"
                     /gene_synonym="NSP-CL"
                     /gene_synonym="RTN-X"
                     /codon_start=1
                     /product="RTN4 protein"
                     /protein_id="AAH71848.1"
                     /db_xref="GeneID:57142"
                     /db_xref="MIM:604475"
                     /translation="MEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAA
                     GAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSK
                     LPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVVVDLL
                     YWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKS
                     DEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLM
                     WVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAK
                     IPGLKRKAE"
BASE COUNT          333 a          394 c          391 g          348 t
ORIGIN      
        1 cacaaccgcc cgcggctctg agacgcggcc ccggcggcgg cggcagcagc tgcagcatca
       61 tctccaccct ccagccatgg aagacgagga ggaagaagag gaggaggaag aggaggacga
      121 ggacgaagac ctggaggagc tggaggtgct ggagaggaag cccgccgccg ggctgtccgc
      181 ggccccagtg cccaccgccc ctgccgccgg cgcgcccctg atggacttcg gaaatgactt
      241 cgtgccgccg gcgccccggg gacccctgcc ggccgctccc cccgtcgccc cggagcggca
      301 gccgtcttgg gacccgagcc cggtgtcgtc gaccgtgccc gcgccatccc cgctgtctgc
      361 tgccgcagtc tcgccctcca agctccctga ggacgacgag cctccggccc ggcctccccc
      421 tcctcccccg gccagcgtga gcccccaggc agagcccgtg tggaccccgc cagccccggc
      481 tcccgccgcg cccccctcca ccccggccgc gcccaagcgc aggggctcct cgggctcagt
      541 ggttgttgac ctcctgtact ggagagacat taagaagact ggagtggtgt ttggtgccag
      601 cctattcctg ctgctttcat tgacagtatt cagcattgtg agcgtaacag cctacattgc
      661 cttggccctg ctctctgtga ccatcagctt taggatatac aagggtgtga tccaagctat
      721 ccagaaatca gatgaaggcc acccattcag ggcatatctg gaatctgaag ttgctatatc
      781 tgaggagttg gttcagaagt acagtaattc tgctcttggt catgtgaact gcacgataaa
      841 ggaactcagg cgcctcttct tagttgatga tttagttgat tctctgaagt ttgcagtgtt
      901 gatgtgggta tttacctatg ttggtgcctt gtttaatggt ctgacactac tgattttggc
      961 tctcatttca ctcttcagtg ttcctgttat ttatgaacgg catcaggcac agatagatca
     1021 ttatctagga cttgcaaata agaatgttaa agatgctatg gctaaaatcc aagcaaaaat
     1081 ccctggattg aagcgcaaag ctgaatgaaa acgcccaaaa taattagtag gagttcatct
     1141 ttaaagggga tattcatttg attatacggg ggagggtcag ggaagaacga accttgacgt
     1201 tgcagtgcag tttcacagat cgttgttaga tctttatttt tagccatgca ctgttgtgag
     1261 gaaaaattac ctgtcttgac tgccatgtgt tcatcatctt aagtattgta agctgctatg
     1321 tatggattta aaccgtaatc atatcttttt cctatctgag gcactggtgg aataaaaaac
     1381 ctgtatattt tactttgttg cagatagtct tgccgcatct tggcaagttg cagagatggt
     1441 ggagctagaa aaaaaaaaaa aaaaaa
//