LOCUS BC071842 1861 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens pyrroline-5-carboxylate reductase 1, mRNA (cDNA clone
MGC:88503 IMAGE:5088067), complete cds.
ACCESSION BC071842
VERSION BC071842.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1861)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1861)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 58 Row: f Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24797096.
FEATURES Location/Qualifiers
source 1..1861
/db_xref="H-InvDB:HIT000264656"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:88503 IMAGE:5088067"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_99"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..1861
/gene="PYCR1"
/gene_synonym="P5C"
/gene_synonym="P5CR"
/gene_synonym="PIG45"
/gene_synonym="PP222"
/gene_synonym="PYCR"
/db_xref="GeneID:5831"
/db_xref="HGNC:HGNC:9721"
/db_xref="MIM:179035"
CDS 63..1022
/gene="PYCR1"
/gene_synonym="P5C"
/gene_synonym="P5CR"
/gene_synonym="PIG45"
/gene_synonym="PP222"
/gene_synonym="PYCR"
/codon_start=1
/product="pyrroline-5-carboxylate reductase 1"
/protein_id="AAH71842.1"
/db_xref="GeneID:5831"
/db_xref="HGNC:HGNC:9721"
/db_xref="MIM:179035"
/translation="MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSA
LRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTIS
SIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCT
EVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLL
HSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQ
VSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD"
BASE COUNT 365 a 586 c 546 g 364 t
ORIGIN
1 ccgcagcgct gagggagccg gtgccatctg tgggggcttt gggccagggg tctccggaca
61 gcatgagcgt gggcttcatc ggcgctggcc agctggcttt tgccctggcc aagggcttca
121 cagcagcagg cgtcttggct gcccacaaga taatggctag ctccccagac atggacctgg
181 ccacagtttc tgctctcagg aagatggggg tgaagttgac accccacaac aaggagacgg
241 tgcagcacag tgatgtgctc ttcctggctg tgaagccaca catcatcccc ttcatcctgg
301 atgaaatagg cgccgacatt gaggacagac acattgtggt gtcctgcgcg gccggcgtca
361 ccatcagctc cattgagaag aagctgtcag cgtttcggcc agcccccagg gtcatccgct
421 gcatgaccaa cactccagtc gtggtgcggg agggggccac cgtgtatgcc acaggcacgc
481 acgcccaggt ggaggacggg aggctcatgg agcagctgct gagcagcgtg ggcttctgca
541 cggaggtgga agaggacctg attgatgccg tcacggggct cagtggcagc ggccccgcct
601 acgcattcac agccctggat gccctggctg atgggggtgt gaagatggga cttccaaggc
661 gcctggcagt ccgcctcggg gcccaggccc tcctgggggc tgccaagatg ctgctgcact
721 cagaacagca cccaggccag ctcaaggaca acgtcagctc tcctggtggg gccaccatcc
781 atgccttgca tgtgctggag agtgggggct tccgctccct gctcatcaac gctgtggagg
841 cctcctgcat ccgcacacgg gagctgcagt ccatggctga ccaggagcag gtgtcaccag
901 ccgccatcaa gaagaccatc ctggacaagg tgaagctgga ctcccctgca gggaccgctc
961 tgtcgccttc tggccacacc aagctgctcc cccgcagcct ggccccagcg ggcaaggatt
1021 gacacgtcct gcctgaccac catcctgcca ccaccttctc ttctcttgtc actaggggga
1081 ctagggggtc cccaaagtgg cccactttct gtggctctga tcagcgcagg ggccagccag
1141 ggacatagcc agggaggggc cacatcactt cccactggaa atctctgtgg tctgcaagtg
1201 cttcccagcc cagaacaggg gtggattccc caacctcaac ctcctttctt ctctgctccc
1261 aaaccatgtc aggaccacct tcctctagag ctcgggagcc cggagggtct tcacccactc
1321 ctactccagt atcagctggc acgggctcct tcctgagagc aaaggtcaag gaccccctct
1381 gtgaaggctc agcagaggtg ggatcccacg ccccctcccg gcccctccct gccctccatt
1441 cagggagaaa cctctccttc ccgtgtgaga agggccagag ggtccaggca tcccaagtcc
1501 agcgtgaagg gccacagccc ctcttggctg ccaagcacgc agatcccatg gacatttggg
1561 gaaagggctc cttgggctgc tggtgaactt ctgtggccac cacctcctgc tcctgacctc
1621 cctgggaggg tgctatcagt tctgtcctgg ccctttcagt tttataagtt ggtttccagc
1681 ccccagtgtc ctgacttctg tctgccacat gaggagggag gccctgcctg tgtgggaggg
1741 tggttactgt gggtggaata gtggaggcct tcaactgatt agacaaggcc cgcccacatc
1801 ttggagggca tctgccttac tgattaaaat gtcaatgtaa tctaaaaaaa aaaaaaaaaa
1861 a
//