LOCUS BC071670 3436 bp mRNA linear HUM 26-JUN-2004
DEFINITION Homo sapiens protein tyrosine phosphatase, non-receptor type 22
(lymphoid), mRNA (cDNA clone MGC:87871 IMAGE:5497108), complete
cds.
ACCESSION BC071670
VERSION BC071670.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3436)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3436)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 166 Row: n Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 15619017.
FEATURES Location/Qualifiers
source 1..3436
/db_xref="H-InvDB:HIT000264494"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87871 IMAGE:5497108"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3436
/gene="PTPN22"
/gene_synonym="LYP"
/gene_synonym="Lyp1"
/gene_synonym="Lyp2"
/db_xref="GeneID:26191"
CDS 76..2334
/gene="PTPN22"
/gene_synonym="LYP"
/gene_synonym="Lyp1"
/gene_synonym="Lyp2"
/codon_start=1
/product="PTPN22 protein"
/protein_id="AAH71670.1"
/db_xref="GeneID:26191"
/translation="MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTY
PTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIAT
QGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSC
EAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQED
DSVPICIHCSAGCGRTGVICAIDYTWMLLKDGSQAKHCIPEKNHTLQADSYSPNLPKS
TTKAAKMMNQQRTKMEIKESSSFDFRTSEISAKEELVLHPAKSSTSFDFLELNYSFDK
NADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEGCSNSKPVNAAGRYFNSKVPITRT
KSTPFELIQQRETKEVDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNYSLPYDS
KHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFP
SSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQESAVLATAPRIDDEIPPPLPVRT
PESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTSEPKKFDDSVILRPSKSVKL
RSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIETYSTSYPDTMENSTSSKQ
TLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNSSSFLNFGFANRFSKP
KGPRNPPPTWNI"
BASE COUNT 1162 a 644 c 585 g 1045 t
ORIGIN
1 ggtgtctcgg ccatgacaca catttgacat gccctccctc aacctactta tagactattt
61 ttcttgctct gcagcatgga ccaaagagaa attctgcaga agttcctgga tgaggcccaa
121 agcaagaaaa ttactaaaga ggagtttgcc aatgaatttc tgaagctgaa aaggcaatct
181 accaagtaca aggcagacaa aacctatcct acaactgtgg ctgagaagcc caagaatatc
241 aagaaaaaca gatataagga tattttgccc tatgattata gccgggtaga actatccctg
301 ataacctctg atgaggattc cagctacatc aatgccaact tcattaaggg agtttatgga
361 cccaaggctt atattgccac ccagggtcct ttatctacaa ccctcctgga cttctggagg
421 atgatttggg aatatagtgt ccttatcatt gttatggcat gcatggagta tgaaatggga
481 aagaaaaagt gtgagcgcta ctgggctgag ccaggagaga tgcagctgga atttggccct
541 ttctctgtat cctgtgaagc tgaaaaaagg aaatctgatt atataatcag gactctaaaa
601 gttaagttca atagtgaaac tcgaactatc taccagtttc attacaagaa ttggccagac
661 catgatgtac cttcatctat agaccctatt cttgagctca tctgggatgt acgttgttac
721 caagaggatg acagtgttcc catatgcatt cactgcagtg ctggctgtgg aaggactggt
781 gttatttgtg ctattgatta tacatggatg ttgctaaaag atgggagtca agcaaagcat
841 tgtattcctg agaaaaatca cactctccaa gcagactctt attctcctaa tttaccaaaa
901 agtaccacaa aagcagcaaa aatgatgaac caacaaagga caaaaatgga aatcaaagaa
961 tcttcttcct ttgactttag gacttctgaa ataagtgcaa aagaagagct agttttgcac
1021 cctgctaaat caagcacttc ttttgacttt ctggagctaa attacagttt tgacaaaaat
1081 gctgacacaa ccatgaaatg gcagacaaag gcatttccaa tagttgggga gcctcttcag
1141 aagcatcaaa gtttggattt gggctctctt ttgtttgagg gatgttctaa ttctaaacct
1201 gtaaatgcag caggaagata ttttaattca aaggtgccaa taacacggac caaatcaact
1261 ccttttgaat tgatacagca gagagaaacc aaggaggtgg acagcaagga aaacttttct
1321 tatttggaat ctcaaccaca tgattcttgt tttgtagaga tgcaggctca aaaagtaatg
1381 catgtttctt cagcagaact gaattattca ctgccatatg actctaaaca ccaaatacgt
1441 aatgcctcta atgtaaagca ccatgactct agtgctcttg gtgtatattc ttacatacct
1501 ttagtggaaa atccttattt ttcatcatgg cctccaagtg gtaccagttc taagatgtct
1561 cttgatttac ctgagaagca agatggaact gtttttcctt cttctctgtt gccaacatcc
1621 tctacatccc tcttctctta ttacaattca catgattctt tatcactgaa ttctccaacc
1681 aatatttcct cactattgaa ccaggagtca gctgtactag caactgctcc aaggatagat
1741 gatgaaatcc cccctccact tcctgtacgg acacctgaat catttattgt ggttgaggaa
1801 gctggagaat tctcaccaaa tgttcccaaa tccttatcct cagctgtgaa ggtaaaaatt
1861 ggaacatcac tggaatgggg tggaacatct gaaccaaaga aatttgatga ctctgtgata
1921 cttagaccaa gcaagagtgt aaaactccga agtcctaaat cagaactaca tcaagatcgt
1981 tcttctcccc cacctcctct cccagaaaga actctagagt ccttctttct tgccgatgaa
2041 gattgtatgc aggcccaatc tatagaaaca tattctacta gctatcctga caccatggaa
2101 aattcaacat cttcaaaaca gacactgaag actcctggaa aaagtttcac aaggagtaag
2161 agtttgaaaa ttttgcgaaa catgaaaaag agtatctgta attcttgccc accaaacaag
2221 cctgcagaat ctgttcagtc aaataactcc agctcatttc tgaattttgg ttttgcaaac
2281 cgtttttcaa aacccaaagg accaaggaat ccaccaccaa cttggaatat ttaataaaac
2341 tccagattta taataatatg ggctgcaagt acacctgcaa ataaaactac tagaatactg
2401 ctagttaaaa taagtgctct atatgcataa tatcaaatat gaagatatgc taatgtgtta
2461 atagctttta aaagaaaagc aaaatgccaa taagtgccag ttttgcattt tcatatcatt
2521 tgcattgagt tgaaaactgc aaataaaagt ttgtcacttg agcttatgta cagaatgcta
2581 tatgagaaac acttttagaa tggatttatt tttcattttt gccagttatt tttattttct
2641 tttacttttt tacataaaca taaacttcaa aaggtttgta agatttggat ctcaactaat
2701 ttctacattg ccagaatata ctataaaaag ttaaaaaaaa aacttacttt gtgggttgca
2761 atacaaactg ctcttgacaa tgactattcc ctgacagtta tttttgccta aatggagtat
2821 accttgtaaa tcttcccaaa tgttgtggaa aactggaata ttaagaaaat gagaaattat
2881 atttattaga ataaaatgtg caaataatga caattatttg aatgtaacaa ggaattcaac
2941 tgaaatcctg ataagtttta accaaagtca ttaaattacc aattctagaa aagtaatcaa
3001 tgaaatataa tagctatctt ttggtagcaa aagatataaa ttgtatatgt ttatacagga
3061 tctttcagat catgtgcaat ttttatctaa ccaatcagaa atactagttt aaaatgaatt
3121 tctatatgaa tatggatctg ccataagaaa atctagttca actctaattt tatgtagtaa
3181 ataaattggc aggtaattgt ttttacaaag aatccacctg acttccccta atgcattaaa
3241 aatattttta tttaaataac tttatttata acttttagaa acatgtagta ttgtttaaac
3301 atcatttgtt cttcagtatt tttcatttgg aagtccaata gggcaaattg aatgaagtat
3361 tattatctgt ctcttgtagt acaatgtatc caacagacac tcaataaact ttttggttgt
3421 taaaaaaaaa aaaaaa
//