LOCUS BC071586 3661 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens TIMP metallopeptidase inhibitor 2, mRNA (cDNA clone
MGC:87301 IMAGE:30337524), complete cds.
ACCESSION BC071586
VERSION BC071586.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3661)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3661)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 168 Row: k Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 52632388.
FEATURES Location/Qualifiers
source 1..3661
/db_xref="H-InvDB:HIT000264415"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87301 IMAGE:30337524"
/tissue_type="Placenta, pre-eclamptic"
/clone_lib="NIH_MGC_148"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3661
/gene="TIMP2"
/gene_synonym="CSC-21K"
/db_xref="GeneID:7077"
/db_xref="HGNC:HGNC:11821"
/db_xref="MIM:188825"
CDS 300..962
/gene="TIMP2"
/gene_synonym="CSC-21K"
/codon_start=1
/product="TIMP metallopeptidase inhibitor 2"
/protein_id="AAH71586.1"
/db_xref="GeneID:7077"
/db_xref="HGNC:HGNC:11821"
/db_xref="MIM:188825"
/translation="MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVV
IRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSL
DVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCP
MIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIE
DP"
BASE COUNT 818 a 1030 c 928 g 885 t
ORIGIN
1 agcaaacaca tccgtagaag gcagcgcggc cgccgagagc cgcagcgccg ctcgcccgcc
61 gccccccacc ccgccgcccc gcccggcgaa ttgcgccccg cgcccctccc ctcgcgcccc
121 cgagacaaag aggagagaaa gtttgcgcgg ccgagcgggg caggtgagga gggtgagccg
181 cgcgggaggg gcccgcctcg gccccggctc agcccccgcc cgcgccccca gcccgccgcc
241 gcgagcagcg cccggacccc ccagcggcgg cccccgcccg cccagccccc cggcccgcca
301 tgggcgccgc ggcccgcacc ctgcggctgg cgctcggcct cctgctgctg gcgacgctgc
361 ttcgcccggc cgacgcctgc agctgctccc cggtgcaccc gcaacaggcg ttttgcaatg
421 cagatgtagt gatcagggcc aaagcggtca gtgagaagga agtggactct ggaaacgaca
481 tttatggcaa ccctatcaag aggatccagt atgagatcaa gcagataaag atgttcaaag
541 ggcctgagaa ggatatagag tttatctaca cggccccctc ctcggcagtg tgtggggtct
601 cgctggacgt tggaggaaag aaggaatatc tcattgcagg aaaggccgag ggggacggca
661 agatgcacat caccctctgt gacttcatcg tgccctggga caccctgagc accacccaga
721 agaagagcct gaaccacagg taccagatgg gctgcgagtg caagatcacg cgctgcccca
781 tgatcccgtg ctacatctcc tccccggacg agtgcctctg gatggactgg gtcacagaga
841 agaacatcaa cgggcaccag gccaagttct tcgcctgcat caagagaagt gacggctcct
901 gtgcgtggta ccgcggcgcg gcgcccccca agcaggagtt tctcgacatc gaggacccat
961 aagcaggcct ccaacgcccc tgtggccaac tgcaaaaaaa gcctccaagg gtttcgactg
1021 gtccagctct gacatccctt cctggaaaca gcatgaataa aacactcatc ccatgggtcc
1081 aaattaatat gattctgctc cccccttctc cttttagaca tggttgtggg tctggaggga
1141 gacgtgggtc caaggtcctc atcccatcct ccctctgcca ggcactatgt gtctggggct
1201 tcgatccttg ggtgcaggca gggctgggac acgcggcttc cctcccagtc cctgccttgg
1261 caccgtcaca gatgccaagc aggcagcact tagggatctc ccagctgggt tagggcaggg
1321 cctggaaatg tgcattttgc agaaactttt gagggtcgtt gcaagactgt gtagcaggcc
1381 taccaggtcc ctttcatctt gagagggaca tggcccttgt tttctgcagc ttccacgcct
1441 ctgcactccc tgcccctggc aagtgctccc atcgccccgg tgcccaccat gagctcccag
1501 cacctgactc cccccacatc caagggcagc ctggaaccag tggctagttc ttgaaggagc
1561 cccatcaatc ctattaatcc tcagaattcc agtgggagcc tccctctgag ccttgtagaa
1621 atgggagcga gaaaccccag ctgagctgcg ttccagcctc agctgagtct ttttggtctg
1681 cacccacccc cccacccccc ccccgcccac atgctcccca gcttgcagga ggaatcggtg
1741 aggtcctgtc ctgaggctgc tgtccggggc cggtggctgc cctcaaggtc ccttccctag
1801 ctgctgcggt tgccattgct tcttgcctgt tctggcatca ggcacctgga ttgagttgca
1861 cagctttgct ttatccgggc ttgtgtgcag ggcccggctg ggctccccat ctgcacatcc
1921 tgaggacaga aaaagctggg tcttgctgtg ccctcccagg cttagtgttc cctccctcaa
1981 agactgacag ccatcgttct gcacggggtt ttctgcatgt gacgccagct aagcatagta
2041 agaagtccag cctaggaagg gaaggatttt ggaggtaggt ggctttggtg acacactcac
2101 ttctttctca gcctccagga cactatggcc tgttttaaga gacatcttat ttttctaaag
2161 gtgaattctc agatgatagg tgaacctgag ttgcagatat accaacttct gcttgtattt
2221 cttaaatgac aaagattacc tagctaagaa acttcctagg gaactaggga acctatgtgt
2281 tccctcagtg tggtttcctg aagccagtga tatgggggtt aggataggaa gaactttctc
2341 ggtaatgata aggagaatct cttgtttcct cccacctgtg ttgtaaagat aaactgacga
2401 tatacaggca cattatgtaa acatacacac gcaatgaaac cgaagcttgg cggcctgggc
2461 gtggtcttgc aaaatgcttc caaagccacc ttagcctgtt ctattcagcg gcaaccccaa
2521 agcacctgtt aagactcctg acccccaagt ggcatgcagc ccccatgccc accgggacct
2581 ggtcagcaca gatcttgatg acttcccttt ctagggcaga ctgggagggt atccaggaat
2641 cggcccctgc cccacgggcg ttttcatgct gtacagtgac ctaaagttgg taagatgtca
2701 taatggacca gtccatgtga tttcagtata tacaactcca ccagacccct ccaacccata
2761 taacacccca cccctgttcg cttcctgtat ggtgatatca tatgtaacat ttactcctgt
2821 ttctgctgat tgttttttta atgttttggt ttgtttttga catcagctgt aatcattcct
2881 gtgctgtgtt ttttattacc cttggtaggt attagacttg cactttttta aaaaaaggtt
2941 tctgcatcgt ggaagcattt gacccagagt ggaacgcgtg gcctatgcag gtggattcct
3001 tcaggtcttt cctttggttc tttgagcatc tttgctttca ttcgtctccc gtctttggtt
3061 ctccagttca aattattgca aagtaaagga tctttgagta ggttcggtct gaaaggtgtg
3121 gcctttatat ttgatccaca cacgttggtc ttttaaccgt gctgagcaga aaacaaaaca
3181 ggttaagaag agccgggtgg cagctgacag aggaagccgc tcaaatacct tcacaataaa
3241 tagtggcaat atatatatag tttaagaagg ctctccattt ggcatcgttt aatttatatg
3301 ttatgttcta agcacagctc tcttctccta ttttcatcct gcaagcaact caaaatattt
3361 aaaataaagt ttacattgta gttattttca aatctttgct tgataagtat taagaaatat
3421 tggacttgct gccgtaattt aaagctctgt tgattttgtt tccgtttgga tttttggggg
3481 aggggagcac tgtgtttatg ctggaatatg aagtctgaga ccttccggtg ctgggaacac
3541 acaagagttg ttgaaagttg acaagcagac tgcgcatgtc tctgatgctt tgtatcattc
3601 ttgagcaatc gctcggtccg tggacaataa acagtattat caaagagaaa aaaaaaaaaa
3661 a
//