LOCUS BC071579 4329 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens mitogen-activated protein kinase kinase kinase kinase
3, mRNA (cDNA clone MGC:87206 IMAGE:5296205), complete cds.
ACCESSION BC071579
VERSION BC071579.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4329)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4329)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 168 Row: d Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 15451901.
FEATURES Location/Qualifiers
source 1..4329
/db_xref="H-InvDB:HIT000264408"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87206 IMAGE:5296205"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4329
/gene="MAP4K3"
/gene_synonym="GLK"
/gene_synonym="MAPKKKK3"
/db_xref="GeneID:8491"
/db_xref="MIM:604921"
CDS 318..2939
/gene="MAP4K3"
/gene_synonym="GLK"
/gene_synonym="MAPKKKK3"
/codon_start=1
/product="MAP4K3 protein"
/protein_id="AAH71579.1"
/db_xref="GeneID:8491"
/db_xref="MIM:604921"
/translation="MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAI
KVIKLEPGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIY
HVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQ
ITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLH
PMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQH
LTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSRNVREEKTRSEITFG
QVKFDPPLRKETEPHHELDLQLEYGQGHQGGYFLGANKSLLKSVEEELHQRGHVAHLE
DDEGDDDESKHSTLKAKIPPPLPPKPKSIFIPQEMHSTEDENQGTIKRCPMSGSPAKP
SQVPPRPPPPRLPPHKPVALGNGMSSFQLNGERDGSLCQQQNEHRGTNLSRKEKKDVP
KPISNGLPPTPKVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLIFGAEEGIYTLN
LNELHETSMEQLFPRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQKLPVA
IPAHKLPDRILPRKFSVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVE
PMQKFMLIKHIDFPIPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNS
TSSWFTESDTPQTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQ
IESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDSTRIFRLLGSDRVVVLESRPTDN
PTANSNLYILAGHENSY"
BASE COUNT 1382 a 794 c 903 g 1250 t
ORIGIN
1 gaggagcggc gaaagcggaa gccatgttgg agtttcaccc cgagcgaggg gctgcgaggg
61 ttctcctctc cttgtgggtg tgaccaggtt cggcgcggcg gcgggccgcg gggggcgggg
121 acgattggcc gcttgtcgtc gtccgcagcg gcgtgagggg agcggcggcg gcggcggcgg
181 cggccgcagc gtggagccgg gtgattgtga ccgccggggg agccgggagc cggccgcggc
241 gccctctctc cgtgtggccc cctgagcggc ccccctcccc tgcccgggag ggaggcgggg
301 ggcacctggg gcccgccatg aaccccggct tcgatttgtc ccgccggaac ccgcaggagg
361 acttcgagct gattcagcgc atcggcagcg gcacctacgg cgacgtctac aaggcacgga
421 atgttaacac tggtgaatta gcagcaatta aagtaataaa attggaacca ggagaagact
481 ttgcagttgt gcagcaagaa attatcatga tgaaagactg taaacaccca aatattgttg
541 cttattttgg aagctatctc aggcgagata agctttggat ttgcatggag ttttgtggag
601 gtggttcttt acaggatatt tatcacgtaa ctggacctct gtcagaactg caaattgcat
661 atgttagcag agaaacactg cagggattat attatcttca cagtaaagga aaaatgcaca
721 gagatataaa gggagctaac attctattaa cggataatgg tcatgtgaaa ttggctgatt
781 ttggagtatc tgcacagata acagctacaa ttgccaaacg gaagtctttc attggcacac
841 catattggat ggctccagaa gttgcagctg ttgagaggaa ggggggttac aatcaactct
901 gtgatctctg ggcagtggga atcactgcca tagaacttgc agagcttcag cctcctatgt
961 ttgacttaca cccaatgaga gcattatttc taatgacaaa aagcaatttt cagcctccta
1021 aactaaagga taaaatgaaa tggtcaaata gttttcatca ctttgtgaaa atggcactta
1081 ccaaaaatcc gaaaaaaaga cctactgctg aaaaattatt acagcatcct tttgtaacac
1141 aacatttgac acggtctttg gcaatcgagc tgttggataa agtaaataat ccagatcatt
1201 ccacttacca tgatttcgat gatgatgatc ctgagcctct tgttgctgta ccacatagaa
1261 ttcactcaac aagtagaaac gtgagagaag aaaaaacacg ctcagagata acctttggcc
1321 aagtgaaatt tgatccaccc ttaagaaagg agacagaacc acatcatgaa cttgatctgc
1381 aactggaata tggacaagga caccaaggtg gttacttttt aggtgcaaac aagagtcttc
1441 tcaagtctgt tgaagaagaa ttgcatcagc gaggacacgt cgcacattta gaagatgatg
1501 aaggagatga tgatgaatct aaacactcaa ctctgaaagc aaaaattcca cctcctttgc
1561 caccaaagcc taagtctatc ttcataccac aggaaatgca ttctactgag gatgaaaatc
1621 aaggaacaat caagagatgt cccatgtcag ggagcccagc aaagccatcc caagttccac
1681 ctagaccacc acctcccaga ttacccccac acaaacctgt tgccttagga aatggaatga
1741 gctccttcca gttaaatggt gaacgagatg gctcattatg tcaacaacag aatgaacata
1801 gaggcacaaa cctttcaaga aaagaaaaga aagatgtacc aaagcctatt agtaatggtc
1861 ttcctccaac acctaaagtg catatgggtg catgtttttc aaaagttttt aatgggtgtc
1921 ccttgaaaat tcactgtgca tcatcatgga taaacccaga tactagagat cagtacttga
1981 tatttggtgc cgaagaaggg atttataccc tcaatcttaa tgaacttcat gaaacatcaa
2041 tggaacagct attccctcga aggtgtacat ggttgtatgt aatgaacaat tgcttgctat
2101 caatatctgg taaagcttct cagctttatt cccataattt accagggctt tttgattatg
2161 caagacaaat gcaaaagtta cctgttgcta ttccagcaca caaactccct gacagaatac
2221 tgccaaggaa attttctgta tcagcaaaaa tccctgaaac caaatggtgc cagaagtgtt
2281 gtgttgtaag aaatccttac acgggccata aatacctatg tggagcactt cagactagca
2341 ttgttctatt agaatgggtt gaaccaatgc agaaatttat gttaattaag cacatagatt
2401 ttcctatacc atgtccactt agaatgtttg aaatgctggt agttcctgaa caggagtacc
2461 ctttagtttg tgttggtgtc agtagaggta gagacttcaa ccaagtggtt cgatttgaga
2521 cggtcaatcc aaattctacc tcttcatggt ttacagaatc agatacccca cagacaaatg
2581 ttactcatgt aacccaactg gagagagata ccatccttgt atgcttggac tgttgtataa
2641 aaatagtaaa tctccaagga agattaaaat ctagcaggaa attgtcatca gaactcacct
2701 ttgatttcca gattgaatca atagtgtgcc tacaagacag tgtgctagct ttctggaaac
2761 atggaatgca aggtagaagt tttagatcta atgaggtaac acaagaaatt tcagatagca
2821 caagaatttt caggctgctt ggatctgaca gggtcgtggt tttggaaagt aggccaactg
2881 ataaccccac agcaaatagc aatttgtaca tcctggcggg tcatgaaaac agttactgag
2941 aattgttgtg ctttgacagt taactctaga aagaaagaac actaccactg caacattaat
3001 ggatgcttga agctgtacaa aagctgcagt aacctgtctt cagttacttt gtaatttatt
3061 gtggcatgag ataagatggg gaaaattttg ttttaagtgg tatggatata tttagcatat
3121 tgaaccacac aagtgcttaa ttcattgtta tgtaatcttt gtacatatag gcagtatttt
3181 ttctgtgaaa cttcatattg ctgaagacat acactaagaa tttatgtaga taatgtactt
3241 ttatgagatg tacaagtaag tgtcttatct gtacagatgt aaatgttgat gaaaatgcaa
3301 ttggggttaa tattttaaga attctttagt atattcttgg gtgtggctat attacaaaat
3361 gggatgctgg caatgaaaca atacatttaa cactattgta tttttattat atgtaattta
3421 gtaatatgaa tataaatctt gtaactttta aaattgtaat ggaggctgta atcattttat
3481 aatcttttta attttaatgc aagtacactg gtgtttatat ttgcacagag tattgatatg
3541 tgatgtatta agtcacaaaa gtaagctgtg acattgtcta taagcatttg gctccacaaa
3601 tgtatttgga ttgttttcta tgtgaagcaa accaattata attaaccaca tgttgtagta
3661 actggtcttt ttatatttaa gcagaatcct gtaagattgc ttgtctttgc ttaaaaacaa
3721 tacctttgaa catttttgaa tcacagaata gcggtaccat gatagaatac tgcaattgtg
3781 gtcagaatta cagtatgcac aaagaattaa ttagcattat taaagagtcc tcactaaaca
3841 tttcatatga tcacactgaa gaactgtaac attccataga gtgaagtggt tcaaatttct
3901 cttggaattt ttacttttgt tggccttatt ttatgatcct tttcatattt cttttgactt
3961 agagtattaa tacatggcca aaataattta gttactacct catacaaaca atataatggt
4021 tactacacat cacaggaact tagttttggt ttaagtcatt tttgattgct tttttccaat
4081 ggaatatgta tataccaggt tttagcaaaa tgcacacttt tggctctttt tggtatatgt
4141 tctttatatt ttaatgtgag tatatacact aagaacaaac taaattgtga tttatgatct
4201 tcatttattt taatggtaat ggttttaaaa tatgttcctg attgtacata ttgtaaaata
4261 aacatgtttt ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4321 aaaaaaaaa
//