LOCUS BC070338 814 bp mRNA linear HUM 06-MAR-2007
DEFINITION Homo sapiens interleukin 2, mRNA (cDNA clone MGC:88343
IMAGE:30418817), complete cds.
ACCESSION BC070338
VERSION BC070338.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 814)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 814)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-MAY-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Narayan Bhat
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 57 Row: p Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 28178860.
FEATURES Location/Qualifiers
source 1..814
/db_xref="H-InvDB:HIT000264293"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:88343 IMAGE:30418817"
/tissue_type="Blood, peripheral blood mononuclear cells
(PBMC) cytoplasmic poly A RNA is pooled sample from 3 and
6 hr after stimulation with PMA and Ionomycin. These
reagents are used to activate T- cells that results in
lymphokine and cytokine production."
/clone_lib="NIH_MGC_191"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..814
/gene="IL2"
/gene_synonym="IL-2"
/gene_synonym="lymphokine"
/gene_synonym="TCGF"
/db_xref="GeneID:3558"
/db_xref="HGNC:HGNC:6001"
/db_xref="MIM:147680"
CDS 48..509
/gene="IL2"
/gene_synonym="IL-2"
/gene_synonym="lymphokine"
/gene_synonym="TCGF"
/codon_start=1
/product="interleukin 2"
/protein_id="AAH70338.1"
/db_xref="GeneID:3558"
/db_xref="HGNC:HGNC:6001"
/db_xref="MIM:147680"
/translation="MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMI
LNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRP
RDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT"
BASE COUNT 294 a 146 c 116 g 258 t
ORIGIN
1 atcactctct ttaatcacta ctcacagtaa cctcaactcc tgccacaatg tacaggatgc
61 aactcctgtc ttgcattgca ctaagtcttg cacttgtcac aaacagtgca cctacttcaa
121 gttctacaaa gaaaacacag ctacaactgg agcatttact gctggattta cagatgattt
181 tgaatggaat taataattac aagaatccca aactcaccag gatgctcaca tttaagtttt
241 acatgcccaa gaaggccaca gaactgaaac atcttcagtg tctagaagaa gaactcaaac
301 ctctggagga agtgctaaat ttagctcaaa gcaaaaactt tcacttaaga cccagggact
361 taatcagcaa tatcaacgta atagttctgg aactaaaggg atctgaaaca acattcatgt
421 gtgaatatgc tgatgagaca gcaaccattg tagaatttct gaacagatgg attacctttt
481 gtcaaagcat catctcaaca ctgacttgat aattaagtgc ttcccactta aaacgtatca
541 ggccttctat ttatttaaat atttaaattt tatatttatt gttgaatgta tggtttgcta
601 cctattgtaa ctattattct taatcttaaa actataaata tggatctttt atgattcttt
661 ttgtaagccc taggggctct aaaatggttt cacttattta tcccaaaata tttattatta
721 tgttgaatgt taaatatagt atctatgtag attggttagt aaaactattt aataaatttg
781 ataaatataa aaaaaaaaaa aaaaaaaaaa aaaa
//