LOCUS BC070261 1193 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens interleukin 22, mRNA (cDNA clone MGC:88248
IMAGE:30416027), complete cds.
ACCESSION BC070261
VERSION BC070261.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1193)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1193)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-MAY-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Narayan Bhat
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 57 Row: p Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 41393566.
FEATURES Location/Qualifiers
source 1..1193
/db_xref="H-InvDB:HIT000264219"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:88248 IMAGE:30416027"
/tissue_type="Blood, peripheral blood mononuclear cells
(PBMC) cytoplasmic poly A RNA is pooled sample from 3 and
6 hr after stimulation with PMA and Ionomycin. These
reagents are used to activate T- cells that results in
lymphokine and cytokine production."
/clone_lib="NIH_MGC_191"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1193
/gene="IL22"
/gene_synonym="IL-21"
/gene_synonym="IL-22"
/gene_synonym="IL-D110"
/gene_synonym="IL-TIF"
/gene_synonym="IL21"
/gene_synonym="ILTIF"
/gene_synonym="TIFa"
/gene_synonym="TIFIL-23"
/gene_synonym="zcyto18"
/db_xref="GeneID:50616"
/db_xref="HGNC:HGNC:14900"
/db_xref="MIM:605330"
CDS 69..608
/gene="IL22"
/gene_synonym="IL-21"
/gene_synonym="IL-22"
/gene_synonym="IL-D110"
/gene_synonym="IL-TIF"
/gene_synonym="IL21"
/gene_synonym="ILTIF"
/gene_synonym="TIFa"
/gene_synonym="TIFIL-23"
/gene_synonym="zcyto18"
/codon_start=1
/product="interleukin 22"
/protein_id="AAH70261.1"
/db_xref="GeneID:50616"
/db_xref="HGNC:HGNC:14900"
/db_xref="MIM:605330"
/translation="MAALQKSVSSFLMGTLATSCLLLLALLVQGGAAAPISSHCRLDK
SNFQQPYITNRTFMLAKEASLADNNTDVRLIGEKLFHGVSMSERCYLMKQVLNFTLEE
VLFPQSDRFQPYMQEVVPFLARLSNRLSTCHIEGDDLHIQRNVQKLKDTVKKLGESGE
IKAIGELDLLFMSLRNACI"
BASE COUNT 378 a 245 c 231 g 339 t
ORIGIN
1 acaagcagaa tcttcagaac aggttctcct tccccagtca ccagttgctc gagttagaat
61 tgtctgcaat ggccgccctg cagaaatctg tgagctcttt ccttatgggg accctggcca
121 ccagctgcct ccttctcttg gccctcttgg tacagggagg agcagctgcg cccatcagct
181 cccactgcag gcttgacaag tccaacttcc agcagcccta tatcaccaac cgcaccttca
241 tgctggctaa ggaggctagc ttggctgata acaacacaga cgttcgtctc attggggaga
301 aactgttcca cggagtcagt atgagtgagc gctgctatct gatgaagcag gtgctgaact
361 tcacccttga agaagtgctg ttccctcaat ctgataggtt ccagccttat atgcaggagg
421 tggtgccctt cctggccagg ctcagcaaca ggctaagcac atgtcatatt gaaggtgatg
481 acctgcatat ccagaggaat gtgcaaaagc tgaaggacac agtgaaaaag cttggagaga
541 gtggagagat caaagcaatt ggagaactgg atttgctgtt tatgtctctg agaaatgcct
601 gcatttgacc agagcaaagc tgaaaaatga ataactaacc ccctttccct gctagaaata
661 acaattagat gccccaaagc gatttttttt aaccaaaagg aagatgggaa gccaaactcc
721 atcatgatgg gtggattcca aatgaacccc tgcgttagtt acaaaggaaa ccaatgccac
781 ttttgtttat aagaccagaa ggtagacttt ctaagcatag atatttattg ataacatttc
841 attgtaactg gtgttctata cacagaaaac aatttatttt ttaaataatt gtctttttcc
901 ataaaaaaga ttactttcca ttcctttagg ggaaaaaacc cctaaatagc ttcatgtttc
961 cataatcagt actttatatt tataaatgta tttattatta ttataagact gcattttatt
1021 tatatcattt tattaatatg gatttattta tagaaacatc attcgatatt gctacttgag
1081 tgtaaggcta atattgatat ttatgacaat aattatagag ctataacatg tttatttgac
1141 ctcaataaac acttggatat ccgaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//