LOCUS BC069651 1380 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens nuclear receptor subfamily 1, group I, member 3, mRNA
(cDNA clone MGC:97144 IMAGE:7262385), complete cds.
ACCESSION BC069651
VERSION BC069651.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1380)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1380)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRBR Plate: 4 Row: a Column: 7
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..1380
/db_xref="H-InvDB:HIT000263802"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:97144 IMAGE:7262385"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_277"
/note="Vector: pPCR-Script Amp SK(+) with reversed insert"
gene 1..1380
/gene="NR1I3"
/gene_synonym="CAR"
/gene_synonym="CAR1"
/gene_synonym="MB67"
/db_xref="GeneID:9970"
/db_xref="HGNC:HGNC:7969"
/db_xref="MIM:603881"
CDS 104..928
/gene="NR1I3"
/gene_synonym="CAR"
/gene_synonym="CAR1"
/gene_synonym="MB67"
/codon_start=1
/product="NR1I3 protein"
/protein_id="AAH69651.1"
/db_xref="GeneID:9970"
/db_xref="HGNC:HGNC:7969"
/db_xref="MIM:603881"
/translation="MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLD
AGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQ
FVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIED
QISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLF
HFHGTLRKLQLQEPEYVLLAAMALFSPGEHLPKPRAFCCTTSAQILSSLSPSTQAF"
BASE COUNT 325 a 423 c 342 g 290 t
ORIGIN
1 taactccaat cactggcaac tcctgagatc agaggaaaac cagcaacagc gtgggagttt
61 ggggagaggc attccatacc agattctgtg gcctgcaggt gacatgctgc ctaagagaag
121 caggagaaca gtcagcaaaa gcattggtcc cacctgcccc tttgctggaa gctgtgaagt
181 cagcaagact cagaggcgcc actgcccagc ctgcaggttg cagaagtgct tagatgctgg
241 catgaggaaa gacatgatac tgtcggcaga agccctggca ttgcggcgag caaagcaggc
301 ccagcggcgg gcacagcaaa cacctgtgca actgagtaag gagcaagaag agctgatccg
361 gacactcctg ggggcccaca cccgccacat gggcaccatg tttgaacagt ttgtgcagtt
421 taggcctcca gctcatctgt tcatccatca ccagcccttg cccaccctgg cccctgtgct
481 gcctctggtc acacacttcg cagacatcaa cactttcatg gtactgcaag tcatcaagtt
541 tactaaggac ctgcccgtct tccgttccct gcccattgaa gaccagatct cccttctcaa
601 gggagcagct gtggaaatct gtcacatcgt actcaatacc actttctgtc tccaaacaca
661 aaacttcctc tgcgggcctc ttcgctacac aattgaagat ggagcccgtg tatctcccac
721 agtggggttc caggtagagt ttttggagtt gctctttcac ttccatggaa cactacgaaa
781 actgcagctc caagagcctg agtatgtgct cttggctgcc atggccctct tctctcctgg
841 tgagcacctc ccaaagccca gagccttttg ctgcaccacc tctgcccaaa tactcagctc
901 cttgagtcca tccacccagg ccttctagcc tagctatcaa acctgcagac taggtctatc
961 ccagcctcag tccccggggc accacgcagg cccacccctg ccacccaact tgtccttccc
1021 agctccctat cttacagacc gacctggagt tacccagaga gatgagattg atcagctgca
1081 agaggagatg gcactgactc tgcaaagcta catcaagggc cagcagcgaa ggccccggga
1141 tcggtttctg tatgcgaagt tgctaggcct gctggctgag ctccggagca ttaatgaggc
1201 ctacgggtac caaatccagc acatccaggg cctgtctgcc atgatgccgc tgctccagga
1261 gatctgcagc tgaggccatg ctcacttcct tccccagctc acctggaaca ccctggatac
1321 actggagtgg gaaaatgctg ggaccaaaga ttgggccggg ttcaaaggga gcccagtggt
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